104 BCMA-targeting CAR-T cells expanded in IL-15 have an improved phenotype for therapeutic use compared to those grown in IL-2 or IL-15/IL-7

by Anthony Battram, Alvaro Urbano-Ispizua, Beatriz Martín-Antonio, Mireia Bachiller
Published 2020-11-01

Natural Killer Cells: Angels and Devils for Immunotherapy

by Beatriz Martín-Antonio, Guillermo Suñe, Lorena Perez-Amill, Maria Castella, Alvaro Urbano-Ispizua
Published 2017-08-01

102 Cord-blood derived NK cells, and CAR-T cells, an attractive improved immunotherapy treatment to be considered for hematological malignancies

by Mireia Bachiller García, Lorena Pérez-Amill, Anthony Battram, Alvaro Urbano-Ispizua, Beatriz Martín-Antonio
Published 2020-11-01

IL-15 Enhances the Persistence and Function of BCMA-Targeting CAR-T Cells Compared to IL-2 or IL-15/IL-7 by Limiting CAR-T Cell Dysfunction and Differentiation

by Anthony M. Battram, Mireia Bachiller, Victor Lopez, Carlos Fernández de Larrea, Alvaro Urbano-Ispizua, Beatriz Martín-Antonio
Published 2021-07-01

Chimeric Antigen Receptor T Cells Targeting CD19 and Ibrutinib for Chronic Lymphocytic Leukemia

by Julio Delgado, Miguel Caballero-Baños, Valentín Ortiz-Maldonado, Maria Castellà, Laura Magnano, Manel Juan, Álvaro Urbano-Ispizua
Published 2019-04-01

CAR-T after Stem Cell Transplantation in B-Cell Lymphoproliferative Disorders: Are They Really Autologous or Allogenic Cell Therapies?

by Ariadna Bartoló-Ibars, Mireia Uribe-Herranz, Guillermo Muñoz-Sánchez, Cristina Arnaldos-Pérez, Valentín Ortiz-Maldonado, Álvaro Urbano-Ispizua, Mariona Pascal, Manel Juan
Published 2021-09-01

Point-Of-Care CAR T-Cell Production (ARI-0001) Using a Closed Semi-automatic Bioreactor: Experience From an Academic Phase I Clinical Trial

by Maria Castella, Maria Castella, Maria Castella, Miguel Caballero-Baños, Miguel Caballero-Baños, Valentín Ortiz-Maldonado, Europa Azucena González-Navarro, Guillermo Suñé, Guillermo Suñé, Asier Antoñana-Vidósola, Asier Antoñana-Vidósola, Anna Boronat, Anna Boronat, Berta Marzal, Lucía Millán, Beatriz Martín-Antonio, Beatriz Martín-Antonio, Joan Cid, Joan Cid, Miquel Lozano, Miquel Lozano, Enric García, Enric García, Jaime Tabera, Jaime Tabera, Esteve Trias, Unai Perpiña, Josep Ma Canals, Josep Ma Canals, Josep Ma Canals, Tycho Baumann, Daniel Benítez-Ribas, Daniel Benítez-Ribas, Elías Campo, Elías Campo, Elías Campo, Elías Campo, Elías Campo, Jordi Yagüe, Jordi Yagüe, Jordi Yagüe, Álvaro Urbano-Ispizua, Álvaro Urbano-Ispizua, Álvaro Urbano-Ispizua, Álvaro Urbano-Ispizua, Álvaro Urbano-Ispizua, Susana Rives, Susana Rives, Julio Delgado, Julio Delgado, Julio Delgado, Julio Delgado, Manel Juan, Manel Juan, Manel Juan, Manel Juan, Manel Juan, Manel Juan
Published 2020-03-01

Cell Banking of HEK293T cell line for clinical-grade lentiviral particles manufacturing

by Unai Perpiñá, Cristina Herranz, Raquel Martín-Ibáñez, Anna Boronat, Felipe Chiappe, Verónica Monforte, Gemma Orpella-Aceret, Ester González, Myriam Olivé, María Castella, Guillermo Suñé, Álvaro Urbano-Ispizua, Julio Delgado, Manel Juan, Josep M. Canals
Published 2020-11-01

Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion

by Joan Isern, Beatriz Martín-Antonio, Roshanak Ghazanfari, Ana M. Martín, Juan A. López, Raquel del Toro, Abel Sánchez-Aguilera, Lorena Arranz, Daniel Martín-Pérez, María Suárez-Lledó, Pedro Marín, Melissa Van Pel, Willem E. Fibbe, Jesús Vázquez, Stefan Scheding, Álvaro Urbano-Ispizúa, Simón Méndez-Ferrer
Published 2013-05-01

IMiDs mobilize acute myeloid leukemia blasts to peripheral blood through downregulation of CXCR4 but fail to potentiate AraC/Idarubicin activity in preclinical models of non del5q/...

by Belen Lopez-Millan, Rafael Diaz de la Guardia, Heleia Roca-Ho, Eduardo Anguita, Abul B. M. M. K. Islam, Damia Romero-Moya, Cristina Prieto, Francisco Gutierrez-Agüera, Jose Antonio Bejarano-Garcia, Jose Antonio Perez-Simon, Paula Costales, Montse Rovira, Pedro Marín, Silvia Menendez, Mar Iglesias, Jose Luis Fuster, Alvaro Urbano-Ispizua, Fernando Anjos-Afonso, Clara Bueno, Pablo Menendez
Published 2018-09-01

The avoidance of G-CSF and the addition of prophylactic corticosteroids after autologous stem cell transplantation for multiple myeloma patients appeal for the at-home setting to r...

by Luis-Gerardo Rodríguez-Lobato, Alexandra Martínez-Roca, Sandra Castaño-Díez, Alicia Palomino-Mosquera, Gonzalo Gutiérrez-García, Alexandra Pedraza, María Suárez-Lledó, Montserrat Rovira, Carmen Martínez, Carlos Fernández de Larrea, María-Teresa Cibeira, Laura Rosiñol, Ester Lozano, Pedro Marín, Joan Cid, Miquel Lozano, Ana Belén Moreno-Castaño, Marta Palomo, Maribel Díaz-Ricart, Cristina Gallego, Adelina Hernando, Susana Segura, Enric Carreras, Álvaro Urbano-Ispizua, Joan Bladé, Francesc Fernández-Avilés
Published 2020-01-01

Development of a Novel Anti-CD19 Chimeric Antigen Receptor: A Paradigm for an Affordable CAR T Cell Production at Academic Institutions

by Maria Castella, Anna Boronat, Raquel Martín-Ibáñez, Vanina Rodríguez, Guillermo Suñé, Miguel Caballero, Berta Marzal, Lorena Pérez-Amill, Beatriz Martín-Antonio, Julio Castaño, Clara Bueno, Olga Balagué, Europa Azucena González-Navarro, Carles Serra-Pages, Pablo Engel, Ramon Vilella, Daniel Benitez-Ribas, Valentín Ortiz-Maldonado, Joan Cid, Jaime Tabera, Josep M. Canals, Miquel Lozano, Tycho Baumann, Anna Vilarrodona, Esteve Trias, Elías Campo, Pablo Menendez, Álvaro Urbano-Ispizua, Jordi Yagüe, Patricia Pérez-Galán, Susana Rives, Julio Delgado, Manel Juan
Published 2019-03-01

The Genotype of the Donor for the (GT)n Polymorphism in the Promoter/Enhancer of FOXP3 Is Associated with the Development of Severe Acute GVHD but Does Not Affect the GVL Effect af...

by Víctor Noriega, Carolina Martínez-Laperche, Elena Buces, Marjorie Pion, Marjorie Pion, Noemí Sánchez-Hernández, Beatriz Martín-Antonio, Vicent Guillem, Anna Bosch-Vizcaya, Leyre Bento, Milagros González-Rivera, Pascual Balsalobre, Mi Kwon, David Serrano, Jorge Gayoso, Rafael de la Cámara, Salut Brunet, Rafael Rojas-Contreras, José B Nieto, Carmen Martínez, Marcos Gónzalez, Ildefonso Espigado, Juan C Vallejo, Antonia Sampol, Antonio Jiménez-Velasco, Alvaro Urbano-Ispizua, Carlos Solano, David Gallardo, José L Díez-Martín, Ismael Buño, Spanish Hematopoietic Stem Cell Transplantation and Cell Therapy Group (GETH)
Published 2015-01-01