Inhibition of NF-κB in Tumor Cells Exacerbates Immune Cell Activation Following Photodynamic Therapy

by Mans Broekgaarden, Milan Kos, Freek A. Jurg, Adriaan A. van Beek, Thomas M. van Gulik, Michal Heger
Published 2015-08-01

Aged mice display altered numbers and phenotype of basophils, and bone marrow-derived basophil activation, with a limited role for aging-associated microbiota

by Adriaan A. van Beek, Floris Fransen, Ben Meijer, Paul de Vos, Edward F. Knol, Huub F. J. Savelkoul
Published 2018-11-01

Supplementation with Lactobacillus plantarum WCFS1 prevents Decline of Mucus Barrier in Colon of Accelerated Aging Ercc1-/Δ7 Mice

by Adriaan A Van Beek, Adriaan A Van Beek, Adriaan A Van Beek, Bruno Sovran, Bruno Sovran, Floor Hugenholtz, Floor Hugenholtz, Ben Meijer, Joanne Hoogerland, Violeta Mihailova, Corine van der Ploeg, Clara Belzer, Clara Belzer, Mark V Boekschoten, Mark V Boekschoten, Jan JH Hoeijmakers, Wilbert P Vermeij, Paul De Vos, Jerry M Wells, Jerry M Wells, Pieter JM Leenen, Claudio Nicoletti, Claudio Nicoletti, Rudi W Hendriks, Huub FJ Savelkoul, Huub FJ Savelkoul
Published 2016-10-01

Aged Gut Microbiota Contributes to Systemical Inflammaging after Transfer to Germ-Free Mice

by Floris Fransen, Floris Fransen, Adriaan A. van Beek, Adriaan A. van Beek, Theo Borghuis, Theo Borghuis, Sahar El Aidy, Floor Hugenholtz, Floor Hugenholtz, Christa van der Gaast – de Jongh, Huub F. J. Savelkoul, Marien I. De Jonge, Mark V. Boekschoten, Mark V. Boekschoten, Hauke Smidt, Hauke Smidt, Marijke M. Faas, Marijke M. Faas, Paul de Vos, Paul de Vos
Published 2017-11-01

The Impact of Gut Microbiota on Gender-Specific Differences in Immunity

by Floris Fransen, Floris Fransen, Adriaan A. van Beek, Adriaan A. van Beek, Theo Borghuis, Theo Borghuis, Ben Meijer, Floor Hugenholtz, Floor Hugenholtz, Christa van der Gaast-de Jongh, Huub F. Savelkoul, Marien I. de Jonge, Marijke M. Faas, Marijke M. Faas, Mark V. Boekschoten, Mark V. Boekschoten, Hauke Smidt, Hauke Smidt, Sahar El Aidy, Paul de Vos, Paul de Vos
Published 2017-06-01

Akkermansia muciniphila ameliorates the age-related decline in colonic mucus thickness and attenuates immune activation in accelerated aging Ercc1 −/Δ7 mice

by Benthe van der Lugt, Adriaan A. van Beek, Steven Aalvink, Ben Meijer, Bruno Sovran, Wilbert P. Vermeij, Renata M. C. Brandt, Willem M. de Vos, Huub F. J. Savelkoul, Wilma T. Steegenga, Clara Belzer
Published 2019-03-01

Blockade of LAG3 enhances responses of tumor-infiltrating T cells in mismatch repair-proficient liver metastases of colorectal cancer

by Guoying Zhou, Lisanne Noordam, Dave Sprengers, Michail Doukas, Patrick P. C. Boor, Adriaan A. van Beek, Remco Erkens, Shanta Mancham, Dirk Grünhagen, Anand G. Menon, Johan F. Lange, Pim J. W. A. Burger, Alexandra Brandt, Boris Galjart, Cornelis Verhoef, Jaap Kwekkeboom, Marco J. Bruno
Published 2018-07-01

FcγRIIB engagement drives agonistic activity of Fc-engineered αOX40 antibody to stimulate human tumor-infiltrating T cells

by Lucia Campos Carrascosa, Adriaan A van Beek, Valeska de Ruiter, Michail Doukas, Timothy S Fisher, Keith Ching, Karlijn van Loon, Patrick P C Boor, Yannick S Rakké, Lisanne Noordam, Pascal Doornebosch, Dirk Grünhagen, Kees Verhoef, Wojciech G Polak, Jan N M IJzermans, Irene Ni, Yik Andy Yeung, Dave Sprengers, Jaap Kwekkeboom
Published 2020-07-01