Skin cornification proteins provide global link between ROS detoxification and cell migration during wound healing.

by Wilbert P Vermeij, Claude Backendorf
Published 2010-01-01

In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration

by Lisanne J. van’t Sant, Joshua J. White, Jan H. J. Hoeijmakers, Wilbert P. Vermeij, Dick Jaarsma
Published 2021-05-01

Akkermansia muciniphila ameliorates the age-related decline in colonic mucus thickness and attenuates immune activation in accelerated aging Ercc1 −/Δ7 mice

by Benthe van der Lugt, Adriaan A. van Beek, Steven Aalvink, Ben Meijer, Bruno Sovran, Wilbert P. Vermeij, Renata M. C. Brandt, Willem M. de Vos, Huub F. J. Savelkoul, Wilma T. Steegenga, Clara Belzer
Published 2019-03-01

Compression of morbidity in a progeroid mouse model through the attenuation of myostatin/activin signalling

by Khalid Alyodawi, Wilbert P. Vermeij, Saleh Omairi, Oliver Kretz, Mark Hopkinson, Francesca Solagna, Barbara Joch, Renata M.C. Brandt, Sander Barnhoorn, Nicole vanVliet, Yanto Ridwan, Jeroen Essers, Robert Mitchell, Taryn Morash, Arja Pasternack, Olli Ritvos, Antonios Matsakas, Henry Collins‐Hooper, Tobias B. Huber, Jan H.J. Hoeijmakers, Ketan Patel
Published 2019-06-01

Cell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiency.

by Sander Barnhoorn, Lieneke M Uittenboogaard, Dick Jaarsma, Wilbert P Vermeij, Maria Tresini, Michael Weymaere, Hervé Menoni, Renata M C Brandt, Monique C de Waard, Sander M Botter, Altaf H Sarker, Nicolaas G J Jaspers, Gijsbertus T J van der Horst, Priscilla K Cooper, Jan H J Hoeijmakers, Ingrid van der Pluijm
Published 2014-10-01

DNA damage and transcription stress cause ATP-mediated redesign of metabolism and potentiation of anti-oxidant buffering

by Chiara Milanese, Cíntia R. Bombardieri, Sara Sepe, Sander Barnhoorn, César Payán-Goméz, Donatella Caruso, Matteo Audano, Silvia Pedretti, Wilbert P. Vermeij, Renata M. C. Brandt, Akos Gyenis, Mirjam M. Wamelink, Annelieke S. de Wit, Roel C. Janssens, René Leen, André B. P. van Kuilenburg, Nico Mitro, Jan H. J. Hoeijmakers, Pier G. Mastroberardino
Published 2019-10-01

Cellular senescence drives age-dependent hepatic steatosis

by Mikolaj Ogrodnik, Satomi Miwa, Tamar Tchkonia, Dina Tiniakos, Caroline L. Wilson, Albert Lahat, Christoper P. Day, Alastair Burt, Allyson Palmer, Quentin M. Anstee, Sushma Nagaraja Grellscheid, Jan H J. Hoeijmakers, Sander Barnhoorn, Derek A. Mann, Thomas G. Bird, Wilbert P. Vermeij, James L. Kirkland, João F. Passos, Thomas von Zglinicki, Diana Jurk
Published 2017-06-01

Supplementation with Lactobacillus plantarum WCFS1 prevents Decline of Mucus Barrier in Colon of Accelerated Aging Ercc1-/Δ7 Mice

by Adriaan A Van Beek, Adriaan A Van Beek, Adriaan A Van Beek, Bruno Sovran, Bruno Sovran, Floor Hugenholtz, Floor Hugenholtz, Ben Meijer, Joanne Hoogerland, Violeta Mihailova, Corine van der Ploeg, Clara Belzer, Clara Belzer, Mark V Boekschoten, Mark V Boekschoten, Jan JH Hoeijmakers, Wilbert P Vermeij, Paul De Vos, Jerry M Wells, Jerry M Wells, Pieter JM Leenen, Claudio Nicoletti, Claudio Nicoletti, Rudi W Hendriks, Huub FJ Savelkoul, Huub FJ Savelkoul
Published 2016-10-01

Tissue-Specific Suppression of Thyroid Hormone Signaling in Various Mouse Models of Aging.

by W Edward Visser, Cíntia R Bombardieri, Chantal Zevenbergen, Sander Barnhoorn, Alexandre Ottaviani, Ingrid van der Pluijm, Renata Brandt, Ellen Kaptein, Ramona van Heerebeek, Hans van Toor, George A Garinis, Robin P Peeters, Marco Medici, Willy van Ham, Wilbert P Vermeij, Monique C de Waard, Ronald R de Krijger, Anita Boelen, Joan Kwakkel, John J Kopchick, Edward O List, Joost P M Melis, Veerle M Darras, Martijn E T Dollé, Gijsbertus T J van der Horst, Jan H J Hoeijmakers, Theo J Visser
Published 2016-01-01