Dynein activating adaptor BICD2 controls radial migration of upper-layer cortical neurons in vivo

by Lena Will, Sybren Portegies, Jasper van Schelt, Merel van Luyk, Dick Jaarsma, Casper C. Hoogenraad
Published 2019-10-01

In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration

by Lisanne J. van’t Sant, Joshua J. White, Jan H. J. Hoeijmakers, Wilbert P. Vermeij, Dick Jaarsma
Published 2021-05-01

Human Cu/Zn Superoxide Dismutase (SOD1) Overexpression in Mice Causes Mitochondrial Vacuolization, Axonal Degeneration, and Premature Motoneuron Death and Accelerates Motoneuron Di...

by Dick Jaarsma, Elize D. Haasdijk, J.A.C. Grashorn, Richard Hawkins, Wim van Duijn, Hein W. Verspaget, Jacqueline London, Jan C. Holstege
Published 2000-12-01

Mechanisms underlying cognitive deficits in a mouse model for Costello Syndrome are distinct from other RASopathy mouse models

by Jadwiga Schreiber, Laura-Anne Grimbergen, Iris Overwater, Thijs van der Vaart, Jeffrey Stedehouder, Alberto J. Schuhmacher, Carmen Guerra, Steven A. Kushner, Dick Jaarsma, Ype Elgersma
Published 2017-04-01

The Copper Metabolism MURR1 domain protein 1 (COMMD1) modulates the aggregation of misfolded protein species in a client-specific manner.

by Willianne I M Vonk, Vaishali Kakkar, Paulina Bartuzi, Dick Jaarsma, Ruud Berger, Marten H Hofker, Leo W J Klomp, Cisca Wijmenga, Harm H Kampinga, Bart van de Sluis
Published 2014-01-01

Characterization of the mouse neuroinvasiveness of selected European strains of West Nile virus.

by Stephanie M Lim, Penelope Koraka, Sander van Boheemen, Jouke M Roose, Dick Jaarsma, David A M C van de Vijver, Albert D M E Osterhaus, Byron E E Martina
Published 2013-01-01

Age-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathology.

by Dick Jaarsma, Ingrid van der Pluijm, Monique C de Waard, Elize D Haasdijk, Renata Brandt, Marcel Vermeij, Yvonne Rijksen, Alex Maas, Harry van Steeg, Jan H J Hoeijmakers, Gijsbertus T J van der Horst
Published 2011-12-01

Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry.

by Daniël Splinter, Marvin E Tanenbaum, Arne Lindqvist, Dick Jaarsma, Annette Flotho, Ka Lou Yu, Ilya Grigoriev, Dieuwke Engelsma, Elize D Haasdijk, Nanda Keijzer, Jeroen Demmers, Maarten Fornerod, Frauke Melchior, Casper C Hoogenraad, René H Medema, Anna Akhmanova
Published 2010-04-01

Pathomechanisms of ALS8: altered autophagy and defective RNA binding protein (RBP) homeostasis due to the VAPB P56S mutation

by Priyanka Tripathi, Haihong Guo, Alice Dreser, Alfred Yamoah, Antonio Sechi, Christopher Marvin Jesse, Istvan Katona, Panagiotis Doukas, Stefan Nikolin, Sabrina Ernst, Eleonora Aronica, Hannes Glaß, Andreas Hermann, Harry Steinbusch, Alfred C. Feller, Markus Bergmann, Dick Jaarsma, Joachim Weis, Anand Goswami
Published 2021-05-01

Correction: Neuron Specific Rab4 Effector GRASP-1 Coordinates Membrane Specialization and Maturation of Recycling Endosomes.

by Casper C. Hoogenraad, Ioana Popa, Kensuke Futai, Emma Martinez-Sanchez, Phebe S. Wulf, Thijs van Vlijmen, Bjorn R. Dortland, Viola Oorschot, Roland Govers, Maria Monti, Albert J. R. Heck, Morgan Sheng, Judith Klumperman, Holger Rehmann, Dick Jaarsma, Lukas C. Kapitein, Peter van der Sluijs
Published 2010-09-01

Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes.

by Casper C Hoogenraad, Ioana Popa, Kensuke Futai, Emma Martinez-Sanchez, Phebe S Wulf, Thijs van Vlijmen, Bjorn R Dortland, Viola Oorschot, Roland Govers, Maria Monti, Albert J R Heck, Morgan Sheng, Judith Klumperman, Holger Rehmann, Dick Jaarsma, Lukas C Kapitein, Peter van der Sluijs
Published 2010-01-01

Cell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiency.

by Sander Barnhoorn, Lieneke M Uittenboogaard, Dick Jaarsma, Wilbert P Vermeij, Maria Tresini, Michael Weymaere, Hervé Menoni, Renata M C Brandt, Monique C de Waard, Sander M Botter, Altaf H Sarker, Nicolaas G J Jaspers, Gijsbertus T J van der Horst, Priscilla K Cooper, Jan H J Hoeijmakers, Ingrid van der Pluijm
Published 2014-10-01