In vitro activity of aryl-thiazole derivatives against Schistosoma mansoni schistosomula and adult worms.

by Adriana S A Pereira, Gilbert O Silveira, Murilo S Amaral, Sinara M V Almeida, Jamerson F Oliveira, Maria C A Lima, Sergio Verjovski-Almeida
Published 2019-01-01

Assessment of reference genes at six different developmental stages of Schistosoma mansoni for quantitative RT-PCR

by Gilbert O. Silveira, Murilo S. Amaral, Helena S. Coelho, Lucas F. Maciel, Adriana S. A. Pereira, Giovanna G. O. Olberg, Patricia A. Miyasato, Eliana Nakano, Sergio Verjovski-Almeida
Published 2021-08-01

Long non-coding RNA levels can be modulated by 5-azacytidine in Schistosoma mansoni

by Murilo S. Amaral, Lucas F. Maciel, Gilbert O. Silveira, Giovanna G. O. Olberg, João V. P. Leite, Lucas K. Imamura, Adriana S. A. Pereira, Patricia A. Miyasato, Eliana Nakano, Sergio Verjovski-Almeida
Published 2020-12-01

Inhibition of histone methyltransferase EZH2 in Schistosoma mansoni in vitro by GSK343 reduces egg laying and decreases the expression of genes implicated in DNA replication and no...

by Adriana S A Pereira, Murilo S Amaral, Elton J R Vasconcelos, David S Pires, Huma Asif, Lucas F daSilva, David A Morales-Vicente, Vitor C Carneiro, Claudia B Angeli, Giuseppe Palmisano, Marcelo R Fantappie, Raymond J Pierce, João C Setubal, Sergio Verjovski-Almeida
Published 2018-10-01

The antischistosomal potential of GSK-J4, an H3K27 demethylase inhibitor: insights from molecular modeling, transcriptomics and in vitro assays

by Jessica Lobo-Silva, Fernanda J. Cabral, Murilo S. Amaral, Patrícia A. Miyasato, Rafaela Paula de Freitas, Adriana S. A. Pereira, Mariana I. Khouri, Mayra M. F. Barbosa, Pablo I. P. Ramos, Luciana C. C. Leite, Oluwatoyin A. Asojo, Eliana Nakano, Sergio Verjovski-Almeida, Leonardo P. Farias
Published 2020-03-01

Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma...

by Vitor Coutinho Carneiro, Isabel Caetano de Abreu da Silva, Murilo Sena Amaral, Adriana S A Pereira, Gilbert Oliveira Silveira, David da Silva Pires, Sergio Verjovski-Almeida, Frank J Dekker, Dante Rotili, Antonello Mai, Eduardo José Lopes-Torres, Dina Robaa, Wolfgang Sippl, Raymond J Pierce, M Teresa Borrello, A Ganesan, Julien Lancelot, Silvana Thiengo, Monica Ammon Fernandez, Amanda Roberta Revoredo Vicentino, Marina Moraes Mourão, Fernanda Sales Coelho, Marcelo Rosado Fantappié
Published 2020-07-01