Editorial: Role of Nrf2 in Disease: Novel Molecular Mechanisms and Therapeutic Approaches

by Javier Egea, Javier Egea, Águeda González-Rodríguez, Águeda González-Rodríguez, Carmen Gómez-Guerrero, Carmen Gómez-Guerrero, Juan Antonio Moreno, Juan Antonio Moreno, Juan Antonio Moreno, Juan Antonio Moreno
Published 2019-10-01

In vivo siRNA delivery of Keap1 modulates death and survival signaling pathways and attenuates concanavalin-A-induced acute liver injury in mice

by Águeda González-Rodríguez, Bjorn Reibert, Thomas Amann, Rainier Constien, Cristina M. Rondinone, Ángela M. Valverde
Published 2014-09-01

Hypoxia and Non-alcoholic Fatty Liver Disease

by Stephania C. Isaza, Elvira del Pozo-Maroto, Lucía Domínguez-Alcón, Liliam Elbouayadi, Águeda González-Rodríguez, Carmelo García-Monzón
Published 2020-10-01

Defective liver glycogen autophagy related to hyperinsulinemia in intrauterine growth-restricted newborn wistar rats

by Juan de Toro-Martín, Tamara Fernández-Marcelo, Águeda González-Rodríguez, Fernando Escrivá, Ángela M. Valverde, Carmen Álvarez, Elisa Fernández-Millán
Published 2020-10-01

Normal proliferation and tumorigenesis but impaired pancreatic function in mice lacking the cell cycle regulator sei1.

by Pablo J Fernandez-Marcos, Cristina Pantoja, Agueda Gonzalez-Rodriguez, Nicholas Martin, Juana M Flores, Angela M Valverde, Eiji Hara, Manuel Serrano
Published 2010-01-01

Increased oxidative stress and apoptosis in the hypothalamus of diabetic male mice in the insulin receptor substrate-2 knockout model

by Eva Baquedano, Emma Burgos-Ramos, Sandra Canelles, Agueda González-Rodríguez, Julie A. Chowen, Jesús Argente, Vicente Barrios, Angela M. Valverde, Laura M. Frago
Published 2016-05-01

Liver-specific insulin receptor isoform A expression enhances hepatic glucose uptake and ameliorates liver steatosis in a mouse model of diet-induced obesity

by Andrea Raposo Lopez-Pastor, Almudena Gomez-Hernandez, Sabela Diaz-Castroverde, Gloria Gonzalez-Aseguinolaza, Agueda Gonzalez-Rodriguez, Gema Garcia, Silvia Fernandez, Oscar Escribano, Manuel Benito
Published 2019-02-01

Intrahepatic Expression of Fatty Acid Translocase CD36 Is Increased in Obstructive Sleep Apnea

by Esther Rey, Elvira del Pozo-Maroto, Patricia Marañón, Brittany Beeler, Yaiza García-García, Pedro Landete, Stephania C. Isaza, Ramón Farré, Carmelo García-Monzón, Isaac Almendros, Águeda González-Rodríguez
Published 2020-08-01

Insulin receptor substrate 2 (IRS2) deficiency delays liver fibrosis associated with cholestatic injury

by Andrea Villar-Lorenzo, Patricia Rada, Esther Rey, Patricia Marañón, Ana I. Arroba, Beatriz Santamaría, Jorge Sáiz, Francisco J. Rupérez, Coral Barbas, Carmelo García-Monzón, Ángela M. Valverde, Águeda González-Rodríguez
Published 2019-07-01

Dual role of protein tyrosine phosphatase 1B in the progression and reversion of non-alcoholic steatohepatitis

by Águeda González-Rodríguez, M. Pilar Valdecantos, Patricia Rada, Annalisa Addante, Inés Barahona, Esther Rey, Virginia Pardo, Laura Ruiz, Laura M. Laiglesia, María J. Moreno-Aliaga, Carmelo García-Monzón, Aránzazu Sánchez, Ángela M. Valverde
Published 2018-01-01

Melatonin Reduces NLRP3 Inflammasome Activation by Increasing α7 nAChR-Mediated Autophagic Flux

by Víctor Farré-Alins, Paloma Narros-Fernández, Alejandra Palomino-Antolín, Céline Decouty-Pérez, Ana Belen Lopez-Rodriguez, Esther Parada, Alicia Muñoz-Montero, Vanessa Gómez-Rangel, Francisco López-Muñoz, Eva Ramos, Águeda González-Rodríguez, Luis Gandía, Alejandro Romero, Javier Egea
Published 2020-12-01

Insulin receptor isoform A ameliorates long-term glucose intolerance in diabetic mice

by Sabela Diaz-Castroverde, Almudena Gómez-Hernández, Silvia Fernández, Gema García-Gómez, Marianna Di Scala, Gloria González-Aseguinolaza, Elisa Fernández-Millán, Águeda González-Rodríguez, María García-Bravo, Pierre Chambon, Carmen Álvarez, Liliana Perdomo, Nuria Beneit, Oscar Escribano, Manuel Benito
Published 2016-11-01

Silencing hepatic MCJ attenuates non-alcoholic fatty liver disease (NAFLD) by increasing mitochondrial fatty acid oxidation

by Lucía Barbier-Torres, Karen A. Fortner, Paula Iruzubieta, Teresa C. Delgado, Emily Giddings, Youdinghuan Chen, Devin Champagne, David Fernández-Ramos, Daniela Mestre, Beatriz Gomez-Santos, Marta Varela-Rey, Virginia Gutiérrez de Juan, Pablo Fernández-Tussy, Imanol Zubiete-Franco, Carmelo García-Monzón, Águeda González-Rodríguez, Dhaval Oza, Felipe Valença-Pereira, Qian Fang, Javier Crespo, Patricia Aspichueta, Frederic Tremblay, Brock C. Christensen, Juan Anguita, María Luz Martínez-Chantar, Mercedes Rincón
Published 2020-07-01