Role and therapeutic effects of skeletal muscle-derived non-myogenic cells in a rat myocardial infarction model

by Hiroko Iseoka, Shigeru Miyagawa, Atsuhiro Saito, Akima Harada, Yoshiki Sawa
Published 2020-02-01

Synthetic Prostacyclin Agonist Attenuates Pressure-Overloaded Cardiac Fibrosis by Inhibiting FMT

by Kenta Masada, Shigeru Miyagawa, Yoshiki Sakai, Akima Harada, Tomomitsu Kanaya, Yoshiki Sawa
Published 2020-12-01

Administration of Slow-Release Synthetic Prostacyclin Agonist Promoted Angiogenesis and Skeletal Muscle Regeneration for Limb Ischemia

by Takaya Nakagawa, Shigeru Miyagawa, Takashi Shibuya, Yoshiki Sakai, Akima Harada, Kenichi Watanabe, Yoshiki Sawa
Published 2020-09-01

Development of a drug screening system using three-dimensional cardiac tissues containing multiple cell types

by Maki Takeda, Shigeru Miyagawa, Emiko Ito, Akima Harada, Noriko Mochizuki-Oda, Michiya Matsusaki, Mitsuru Akashi, Yoshiki Sawa
Published 2021-03-01

Notch signaling-modified mesenchymal stem cells improve tissue perfusion by induction of arteriogenesis in a rat hindlimb ischemia model

by Shusaku Maeda, Shigeru Miyagawa, Takuji Kawamura, Takashi Shibuya, Kenichi Watanabe, Takaya Nakagawa, Akima Harada, Dai Chida, Yoshiki Sawa
Published 2021-01-01

High-mobility group box 1 fragment suppresses adverse post-infarction remodeling by recruiting PDGFRα-positive bone marrow cells.

by Takasumi Goto, Shigeru Miyagawa, Katsuto Tamai, Ryohei Matsuura, Takashi Kido, Toru Kuratani, Kazuo Shimamura, Ryoto Sakaniwa, Akima Harada, Yoshiki Sawa
Published 2020-01-01

Autologous skeletal myoblast patch implantation prevents the deterioration of myocardial ischemia and right heart dysfunction in a pressure-overloaded right heart porcine model.

by Kanta Araki, Shigeru Miyagawa, Takuji Kawamura, Ryo Ishii, Tadashi Watabe, Akima Harada, Masaki Taira, Koichi Toda, Toru Kuratani, Takayoshi Ueno, Yoshiki Sawa
Published 2021-01-01

Immunologic targeting of CD30 eliminates tumourigenic human pluripotent stem cells, allowing safer clinical application of hiPSC-based cell therapy

by Nagako Sougawa, Shigeru Miyagawa, Satsuki Fukushima, Ai Kawamura, Junya Yokoyama, Emiko Ito, Akima Harada, Kaori Okimoto, Noriko Mochizuki-Oda, Atsuhiro Saito, Yoshiki Sawa
Published 2018-02-01

Vasculogenically conditioned peripheral blood mononuclear cells inhibit mouse immune response to induced pluripotent stem cell-derived allogeneic cardiac grafts.

by Noriyuki Kashiyama, Shigeru Miyagawa, Satsuki Fukushima, Takuji Kawamura, Ai Kawamura, Shohei Yoshida, Yuki Nakamura, Akima Harada, Haruchika Masuda, Koichi Toda, Takayuki Asahara, Yoshiki Sawa
Published 2019-01-01

Improvement of Cardiac Stem Cell Sheet Therapy for Chronic Ischemic Injury by Adding Endothelial Progenitor Cell Transplantation: Analysis of Layer-Specific Regional Cardiac Functi...

by Sokichi Kamata, Shigeru Miyagawa, Satsuki Fukushima, Satoshi Nakatani, Atsuhiko Kawamoto, Atsuhiro Saito, Akima Harada, Tatsuya Shimizu, Takashi Daimon, Teruo Okano, Takayuki Asahara, Yoshiki Sawa
Published 2014-10-01

Development of PET Imaging to Visualize Activated Macrophages Accumulated in the Transplanted iPSc-Derived Cardiac Myocytes of Allogeneic Origin for Detecting the Immune Rejection...

by Noriyuki Kashiyama, Shigeru Miyagawa, Satsuki Fukushima, Takuji Kawamura, Ai Kawamura, Shohei Yoshida, Akima Harada, Tadashi Watabe, Yasukazu Kanai, Koichi Toda, Jun Hatazawa, Yoshiki Sawa
Published 2016-01-01

Influence of coronary architecture on the variability in myocardial infarction induced by coronary ligation in rats.

by Satoshi Kainuma, Shigeru Miyagawa, Satsuki Fukushima, Hirotsugu Tsuchimochi, Takashi Sonobe, Yutaka Fujii, James T Pearson, Atsuhiro Saito, Akima Harada, Koichi Toda, Mikiyasu Shirai, Yoshiki Sawa
Published 2017-01-01

Prostacyclin Analogue–Loaded Nanoparticles Attenuate Myocardial Ischemia/Reperfusion Injury in Rats

by Shin Yajima, MD, PhD, Shigeru Miyagawa, MD, PhD, Satsuki Fukushima, MD, PhD, Yoshiki Sakai, BSc, Hiroko Iseoka, PhD, Akima Harada, BSc, Kayako Isohashi, MD, PhD, Genki Horitsugi, BSc, Yuki Mori, PhD, Motoko Shiozaki, PhD, Hirotatsu Ohkawara, PhD, Ryoto Sakaniwa, PhD, Jun Hatazawa, MD, PhD, Yoshichika Yoshioka, PhD, Yoshiki Sawa, MD, PhD
Published 2019-06-01