The Role Played by Wnt/β-Catenin Signaling Pathway in Acute Lymphoblastic Leukemia

by Francesca Chiarini, Francesca Paganelli, Alberto M. Martelli, Camilla Evangelisti
Published 2020-02-01

Therapeutic Targeting of mTOR in T-Cell Acute Lymphoblastic Leukemia: An Update

by Camilla Evangelisti, Francesca Chiarini, James A. McCubrey, Alberto M. Martelli
Published 2018-06-01

Targeting mTOR in Acute Lymphoblastic Leukemia

by Carolina Simioni, Alberto M. Martelli, Giorgio Zauli, Elisabetta Melloni, Luca M. Neri
Published 2019-02-01

The Unfolded Protein Response: A Novel Therapeutic Target in Acute Leukemias

by Alberto M. Martelli, Francesca Paganelli, Francesca Chiarini, Camilla Evangelisti, James A. McCubrey
Published 2020-02-01

The Emerging Role of the Phosphatidylinositol 3-Kinase/ Akt/Mammalian Target of Rapamycin Signaling Network in Cancer Stem Cell Biology

by James A. McCubrey, Camilla Evangelisti, Cecilia Grimaldi, Francesca Chiarini, Alberto M. Martelli
Published 2010-08-01

The Key Roles of PTEN in T-Cell Acute Lymphoblastic Leukemia Development, Progression, and Therapeutic Response

by Alberto M. Martelli, Francesca Paganelli, Antonietta Fazio, Chiara Bazzichetto, Fabiana Conciatori, James A. McCubrey
Published 2019-05-01

The Cutting Edge: The Role of mTOR Signaling in Laminopathies

by Francesca Chiarini, Camilla Evangelisti, Vittoria Cenni, Antonietta Fazio, Francesca Paganelli, Alberto M. Martelli, Giovanna Lattanzi
Published 2019-02-01

B-ALL Complexity: Is Targeted Therapy Still A Valuable Approach for Pediatric Patients?

by Stefano Ratti, Annalisa Lonetti, Matilde Y. Follo, Francesca Paganelli, Alberto M. Martelli, Francesca Chiarini, Camilla Evangelisti
Published 2020-11-01

Marine bisindole alkaloid: A potential apoptotic inducer in human cancer cells

by Sara Salucci, Sabrina Burattini, Francesca Buontempo, Ester Orsini, Lucia Furiassi, Michele Mari, Simone Lucarini, Alberto M. Martelli, Elisabetta Falcieri
Published 2018-04-01

Inhibition of Methyltransferase DOT1L Sensitizes to Sorafenib Treatment AML Cells Irrespective of <i>MLL</i>-Rearrangements: A Novel Therapeutic Strategy for Pediatric AML

by Annalisa Lonetti, Valentina Indio, Maria Antonella Laginestra, Giuseppe Tarantino, Francesca Chiarini, Annalisa Astolfi, Salvatore N. Bertuccio, Alberto M. Martelli, Franco Locatelli, Andrea Pession, Riccardo Masetti
Published 2020-07-01

Lamin A and Prelamin a Counteract Migration of Osteosarcoma Cells

by Camilla Evangelisti, Francesca Paganelli, Gaia Giuntini, Elisabetta Mattioli, Alessandra Cappellini, Giulia Ramazzotti, Irene Faenza, Maria Cristina Maltarello, Alberto M. Martelli, Katia Scotlandi, Francesca Chiarini, Giovanna Lattanzi
Published 2020-03-01

Targeting GSK3 and Associated Signaling Pathways Involved in Cancer

by Przemysław Duda, Shaw M. Akula, Stephen L. Abrams, Linda S. Steelman, Alberto M. Martelli, Lucio Cocco, Stefano Ratti, Saverio Candido, Massimo Libra, Giuseppe Montalto, Melchiorre Cervello, Agnieszka Gizak, Dariusz Rakus, James A. McCubrey
Published 2020-04-01

GSK-3β Can Regulate the Sensitivity of MIA-PaCa-2 Pancreatic and MCF-7 Breast Cancer Cells to Chemotherapeutic Drugs, Targeted Therapeutics and Nutraceuticals

by Stephen L. Abrams, Shaw M. Akula, Akshaya K. Meher, Linda S. Steelman, Agnieszka Gizak, Przemysław Duda, Dariusz Rakus, Alberto M. Martelli, Stefano Ratti, Lucio Cocco, Giuseppe Montalto, Melchiorre Cervello, Peter Ruvolo, Massimo Libra, Luca Falzone, Saverio Candido, James A. McCubrey
Published 2021-04-01