Therapeutic Targeting of mTOR in T-Cell Acute Lymphoblastic Leukemia: An Update

by Camilla Evangelisti, Francesca Chiarini, James A. McCubrey, Alberto M. Martelli
Published 2018-06-01

The Reverse Warburg Effect Is Associated with Fbp2-Dependent Hif1α Regulation in Cancer Cells Stimulated by Fibroblasts

by Przemysław Duda, Jakub Janczara, James A. McCubrey, Agnieszka Gizak, Dariusz Rakus
Published 2020-01-01

The Unfolded Protein Response: A Novel Therapeutic Target in Acute Leukemias

by Alberto M. Martelli, Francesca Paganelli, Francesca Chiarini, Camilla Evangelisti, James A. McCubrey
Published 2020-02-01

The Emerging Role of the Phosphatidylinositol 3-Kinase/ Akt/Mammalian Target of Rapamycin Signaling Network in Cancer Stem Cell Biology

by James A. McCubrey, Camilla Evangelisti, Cecilia Grimaldi, Francesca Chiarini, Alberto M. Martelli
Published 2010-08-01

GSK3 as a Regulator of Cytoskeleton Architecture: Consequences for Health and Disease

by Daria Hajka, Bartosz Budziak, Łukasz Pietras, Przemysław Duda, James A. McCubrey, Agnieszka Gizak
Published 2021-08-01

The Key Roles of PTEN in T-Cell Acute Lymphoblastic Leukemia Development, Progression, and Therapeutic Response

by Alberto M. Martelli, Francesca Paganelli, Antonietta Fazio, Chiara Bazzichetto, Fabiana Conciatori, James A. McCubrey
Published 2019-05-01

Novel combination of sorafenib and celecoxib provides synergistic anti-proliferative and pro-apoptotic effects in human liver cancer cells.

by Melchiorre Cervello, Dimcho Bachvarov, Nadia Lampiasi, Antonella Cusimano, Antonina Azzolina, James A McCubrey, Giuseppe Montalto
Published 2013-01-01

Antitumor Mechanism of the Essential Oils from Two Succulent Plants in Multidrug Resistance Leukemia Cell

by Paola Poma, Manuela Labbozzetta, James A. McCubrey, Aro Vonjy Ramarosandratana, Maurizio Sajeva, Pietro Zito, Monica Notarbartolo
Published 2019-08-01

The Role of GSK-3 in Cancer Immunotherapy: GSK-3 Inhibitors as a New Frontier in Cancer Treatment

by Giuseppa Augello, Maria R. Emma, Antonella Cusimano, Antonina Azzolina, Giuseppe Montalto, James A. McCubrey, Melchiorre Cervello
Published 2020-06-01

Recent Progress in Discovering the Role of Carotenoids and Metabolites in Prostatic Physiology and Pathology—A Review—Part II: Carotenoids in the Human Studies

by Joanna Dulińska-Litewka, Przemysław Hałubiec, Agnieszka Łazarczyk, Oskar Szafrański, Yoav Sharoni, James A. McCubrey, Bartosz Gąsiorkiewicz, Torsten Bohn
Published 2021-02-01

Computational Modeling of PI3K/AKT and MAPK Signaling Pathways in Melanoma Cancer.

by Francesco Pappalardo, Giulia Russo, Saverio Candido, Marzio Pennisi, Salvatore Cavalieri, Santo Motta, James A McCubrey, Ferdinando Nicoletti, Massimo Libra
Published 2016-01-01

Recent Progress in Discovering the Role of Carotenoids and Their Metabolites in Prostatic Physiology and Pathology with a Focus on Prostate Cancer—A Review—Part I: Molecular Mechan...

by Joanna Dulińska-Litewka, Yoav Sharoni, Przemysław Hałubiec, Agnieszka Łazarczyk, Oskar Szafrański, James A. McCubrey, Bartosz Gąsiorkiewicz, Piotr Laidler, Torsten Bohn
Published 2021-04-01

Nuclear phospholipase C isoenzyme imbalance leads to pathologies in brain, hematologic, neuromuscular, and fertility disorders[S]

by Stefano Ratti, Matilde Y. Follo, Giulia Ramazzotti, Irene Faenza, Roberta Fiume, Pann-Ghill Suh, James A. McCubrey, Lucia Manzoli, Lucio Cocco
Published 2019-02-01

Subcellular Localization Relevance and Cancer-Associated Mechanisms of Diacylglycerol Kinases

by Antonietta Fazio, Eric Owusu Obeng, Isabella Rusciano, Maria Vittoria Marvi, Matteo Zoli, Sara Mongiorgi, Giulia Ramazzotti, Matilde Yung Follo, James A. McCubrey, Lucio Cocco, Lucia Manzoli, Stefano Ratti
Published 2020-07-01

Targeting GSK3 and Associated Signaling Pathways Involved in Cancer

by Przemysław Duda, Shaw M. Akula, Stephen L. Abrams, Linda S. Steelman, Alberto M. Martelli, Lucio Cocco, Stefano Ratti, Saverio Candido, Massimo Libra, Giuseppe Montalto, Melchiorre Cervello, Agnieszka Gizak, Dariusz Rakus, James A. McCubrey
Published 2020-04-01

GSK-3β Can Regulate the Sensitivity of MIA-PaCa-2 Pancreatic and MCF-7 Breast Cancer Cells to Chemotherapeutic Drugs, Targeted Therapeutics and Nutraceuticals

by Stephen L. Abrams, Shaw M. Akula, Akshaya K. Meher, Linda S. Steelman, Agnieszka Gizak, Przemysław Duda, Dariusz Rakus, Alberto M. Martelli, Stefano Ratti, Lucio Cocco, Giuseppe Montalto, Melchiorre Cervello, Peter Ruvolo, Massimo Libra, Luca Falzone, Saverio Candido, James A. McCubrey
Published 2021-04-01