The Anti-mycobacterial Activity of a Diterpenoid-Like Molecule Operates Through Nitrogen and Amino Acid Starvation

by Alessandra Crusco, Alessandra Crusco, Rafael Baptista, Sumana Bhowmick, Manfred Beckmann, Luis A. J. Mur, Andrew D. Westwell, Karl F. Hoffmann
Published 2019-06-01

Quorum sensing N-Acyl homoserine lactones are a new class of anti-schistosomal.

by Helen Whiteland, Alessandra Crusco, Lisa W Bloemberg, Jamie Tibble-Howlings, Josephine Forde-Thomas, Avril Coghlan, Patrick J Murphy, Karl F Hoffmann
Published 2020-10-01

An Abies procera-derived tetracyclic triterpene containing a steroid-like nucleus core and a lactone side chain attenuates in vitro survival of both Fasciola hepatica and Schistoso...

by Helen L. Whiteland, Anand Chakroborty, Josephine E. Forde-Thomas, Alessandra Crusco, Alan Cookson, Jackie Hollinshead, Caroline A. Fenn, Barbara Bartholomew, Peter A. Holdsworth, Maggie Fisher, Robert J. Nash, Karl F. Hoffmann
Published 2018-12-01