The PPE domain of PPE17 is responsible for its surface localization and can be used to express heterologous proteins on the mycobacterial surface.

by Valentina Donà, Marcello Ventura, Michela Sali, Alessandro Cascioferro, Roberta Provvedi, Giorgio Palù, Giovanni Delogu, Riccardo Manganelli
Published 2013-01-01

Functional dissection of the PE domain responsible for translocation of PE_PGRS33 across the mycobacterial cell wall.

by Alessandro Cascioferro, Maria H Daleke, Marcello Ventura, Valentina Donà, Giovanni Delogu, Giorgio Palù, Wilbert Bitter, Riccardo Manganelli
Published 2011-01-01

PE_PGRS33 Contributes to Mycobacterium tuberculosis Entry in Macrophages through Interaction with TLR2.

by Ivana Palucci, Serena Camassa, Alessandro Cascioferro, Michela Sali, Saber Anoosheh, Antonella Zumbo, Mariachiara Minerva, Raffaella Iantomasi, Flavio De Maio, Gabriele Di Sante, Francesco Ria, Maurizio Sanguinetti, Giorgio Palù, Michael J Brennan, Riccardo Manganelli, Giovanni Delogu
Published 2016-01-01

PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis.

by Barbara Rieck, Giulia Degiacomi, Michael Zimmermann, Alessandro Cascioferro, Francesca Boldrin, Natalie R Lazar-Adler, Andrew R Bottrill, Fabien le Chevalier, Wafa Frigui, Marco Bellinzoni, María-Natalia Lisa, Pedro M Alzari, Liem Nguyen, Roland Brosch, Uwe Sauer, Riccardo Manganelli, Helen M O'Hare
Published 2017-05-01