Exploring the fatty acid amide hydrolase and cyclooxygenase inhibitory properties of novel amide derivatives of ibuprofen

by Alessandro Deplano, Jessica Karlsson, Mona Svensson, Federica Moraca, Bruno Catalanotti, Christopher J. Fowler, Valentina Onnis
Published 2020-01-01

Benzylamides and piperazinoarylamides of ibuprofen as fatty acid amide hydrolase inhibitors

by Alessandro Deplano, Mariateresa Cipriano, Federica Moraca, Ettore Novellino, Bruno Catalanotti, Christopher J. Fowler, Valentina Onnis
Published 2019-01-01

Design, Synthesis and Evaluation of Antiproliferative Activity of New Benzimidazolehydrazones

by Valentina Onnis, Monica Demurtas, Alessandro Deplano, Gianfranco Balboni, Anna Baldisserotto, Stefano Manfredini, Salvatore Pacifico, Sandra Liekens, Jan Balzarini
Published 2016-04-01

Characterisation of (R)-2-(2-Fluorobiphenyl-4-yl)-N-(3-Methylpyridin-2-yl)Propanamide as a Dual Fatty Acid Amide Hydrolase: Cyclooxygenase Inhibitor.

by Sandra Gouveia-Figueira, Jessica Karlsson, Alessandro Deplano, Sanaz Hashemian, Mona Svensson, Marcus Fredriksson Sundbom, Cenzo Congiu, Valentina Onnis, Christopher J Fowler
Published 2015-01-01

Design, synthesis and in vitro and in vivo biological evaluation of flurbiprofen amides as new fatty acid amide hydrolase/cyclooxygenase-2 dual inhibitory potential analgesic agent...

by Alessandro Deplano, Jessica Karlsson, Federica Moraca, Mona Svensson, Claudia Cristiano, Carmine Marco Morgillo, Christopher J. Fowler, Roberto Russo, Bruno Catalanotti, Valentina Onnis
Published 2021-01-01

Interaction of the N-(3-Methylpyridin-2-yl)amide Derivatives of Flurbiprofen and Ibuprofen with FAAH: Enantiomeric Selectivity and Binding Mode.

by Jessica Karlsson, Carmine M Morgillo, Alessandro Deplano, Giovanni Smaldone, Emilia Pedone, F Javier Luque, Mona Svensson, Ettore Novellino, Cenzo Congiu, Valentina Onnis, Bruno Catalanotti, Christopher J Fowler
Published 2015-01-01