Metformin as Host-Directed Therapy for TB Treatment: Scoping Review

by Nikita Naicker, Alex Sigal, Alex Sigal, Alex Sigal, Kogieleum Naidoo, Kogieleum Naidoo
Published 2020-04-01

Dendritic cells efficiently transmit HIV to T Cells in a tenofovir and raltegravir insensitive manner.

by Jocelyn T Kim, Emery Chang, Alex Sigal, David Baltimore
Published 2018-01-01

Interference with HIV infection of the first cell is essential for viral clearance at sub-optimal levels of drug inhibition.

by Ana Moyano, Gila Lustig, Hylton E Rodel, Tibor Antal, Alex Sigal
Published 2020-02-01

Viral Apoptosis Evasion via the MAPK Pathway by Use of a Host Long Noncoding RNA

by Samantha Barichievy, Samantha Barichievy, Jerolen Naidoo, Jerolen Naidoo, Mikaël Boullé, Mikaël Boullé, Mikaël Boullé, Janine Scholefield, Suraj P. Parihar, Suraj P. Parihar, Anna K. Coussens, Frank Brombacher, Frank Brombacher, Alex Sigal, Alex Sigal, Alex Sigal, Musa M. Mhlanga, Musa M. Mhlanga, Musa M. Mhlanga
Published 2018-08-01

Fabrication principles and their contribution to the superior in vivo therapeutic efficacy of nano-liposomes remote loaded with glucocorticoids.

by Yuval Avnir, Keren Turjeman, Deborah Tulchinsky, Alex Sigal, Pablo Kizelsztein, Dina Tzemach, Alberto Gabizon, Yechezkel Barenholz
Published 2011-01-01

Diminished HIV Infection of Target CD4+ T Cells in a Toll-Like Receptor 4 Stimulated in vitro Model

by Ross Cromarty, Alex Sigal, Alex Sigal, Lenine J. P. Liebenberg, Lenine J. P. Liebenberg, Lyle R. McKinnon, Lyle R. McKinnon, Salim S. Abdool Karim, Salim S. Abdool Karim, Jo-Ann S. Passmore, Jo-Ann S. Passmore, Jo-Ann S. Passmore, Derseree Archary, Derseree Archary
Published 2019-07-01

Dynamic proteomics of human protein level and localization across the cell cycle.

by Shlomit Farkash-Amar, Eran Eden, Ariel Cohen, Naama Geva-Zatorsky, Lydia Cohen, Ron Milo, Alex Sigal, Tamar Danon, Uri Alon
Published 2012-01-01

HIV Cell-to-Cell Spread Results in Earlier Onset of Viral Gene Expression by Multiple Infections per Cell.

by Mikaël Boullé, Thorsten G Müller, Sabrina Dähling, Yashica Ganga, Laurelle Jackson, Deeqa Mahamed, Lance Oom, Gila Lustig, Richard A Neher, Alex Sigal
Published 2016-11-01

Noise genetics: inferring protein function by correlating phenotype with protein levels and localization in individual human cells.

by Shlomit Farkash-Amar, Anat Zimmer, Eran Eden, Ariel Cohen, Naama Geva-Zatorsky, Lydia Cohen, Ron Milo, Alex Sigal, Tamar Danon, Uri Alon
Published 2014-03-01

Protein dynamics in individual human cells: experiment and theory.

by Ariel Aharon Cohen, Tomer Kalisky, Avi Mayo, Naama Geva-Zatorsky, Tamar Danon, Irina Issaeva, Ronen Benjamine Kopito, Natalie Perzov, Ron Milo, Alex Sigal, Uri Alon
Published 2009-01-01

Intracellular growth of Mycobacterium tuberculosis after macrophage cell death leads to serial killing of host cells

by Deeqa Mahamed, Mikael Boulle, Yashica Ganga, Chanelle Mc Arthur, Steven Skroch, Lance Oom, Oana Catinas, Kelly Pillay, Myshnee Naicker, Sanisha Rampersad, Colisile Mathonsi, Jessica Hunter, Emily B Wong, Moosa Suleman, Gopalkrishna Sreejit, Alexander S Pym, Gila Lustig, Alex Sigal
Published 2017-01-01

Incomplete inhibition of HIV infection results in more HIV infected lymph node cells by reducing cell death

by Laurelle Jackson, Jessica Hunter, Sandile Cele, Isabella Markham Ferreira, Andrew C Young, Farina Karim, Rajhmun Madansein, Kaylesh J Dullabh, Chih-Yuan Chen, Noel J Buckels, Yashica Ganga, Khadija Khan, Mikael Boulle, Gila Lustig, Richard A Neher, Alex Sigal
Published 2018-03-01

Correction: Intracellular growth of Mycobacterium tuberculosis after macrophage cell death leads to serial killing of host cells

by Deeqa Mahamed, Mikael Boulle, Yashica Ganga, Chanelle Mc Arthur, Steven Skroch, Lance Oom, Oana Catinas, Kelly Pillay, Myshnee Naicker, Sanisha Rampersad, Colisile Mathonsi, Jessica Hunter, Emily B Wong, Moosa Suleman, Gopalkrishna Sreejit, Alexander S Pym, Gila Lustig, Alex Sigal
Published 2017-05-01

Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains

by Nikhil Faulkner, Kevin W Ng, Mary Y Wu, Ruth Harvey, Marios Margaritis, Stavroula Paraskevopoulou, Catherine Houlihan, Saira Hussain, Maria Greco, William Bolland, Scott Warchal, Judith Heaney, Hannah Rickman, Moria Spyer, Daniel Frampton, Matthew Byott, Tulio de Oliveira, Alex Sigal, Svend Kjaer, Charles Swanton, Sonia Gandhi, Rupert Beale, Steve J Gamblin, John W McCauley, Rodney Stuart Daniels, Michael Howell, David Bauer, Eleni Nastouli, George Kassiotis
Published 2021-07-01

Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern

by Donal T. Skelly, Adam C. Harding, Javier Gilbert-Jaramillo, Michael L. Knight, Stephanie Longet, Anthony Brown, Sandra Adele, Emily Adland, Helen Brown, Medawar Laboratory Team, Tom Tipton, Lizzie Stafford, Alexander J. Mentzer, Síle A. Johnson, Ali Amini, OPTIC (Oxford Protective T cell Immunology for COVID-19) Clinical Group, Tiong Kit Tan, Lisa Schimanski, Kuan-Ying A. Huang, Pramila Rijal, PITCH (Protective Immunity T cells in Health Care Worker) Study Group, C-MORE/PHOSP-C Group, John Frater, Philip Goulder, Christopher P. Conlon, Katie Jeffery, Christina Dold, Andrew J. Pollard, Alex Sigal, Tulio de Oliveira, Alain R. Townsend, Paul Klenerman, Susanna J. Dunachie, Eleanor Barnes, Miles W. Carroll, William S. James
Published 2021-08-01

TBVAC2020: Advancing Tuberculosis Vaccines from Discovery to Clinical Development

by Stefan H. E. Kaufmann, Hazel M. Dockrell, Nick Drager, Mei Mei Ho, Helen McShane, Olivier Neyrolles, Tom H. M. Ottenhoff, Brij Patel, Danielle Roordink, François Spertini, Steffen Stenger, Jelle Thole, Frank A. W. Verreck, Ann Williams, TBVAC2020 Consortium, Warwick Britton, Jamie Triccas, Claudio Counoupas, Johan Grooten, Marie-Ange Demoitie, Marta Romano, Francoise Mascart, Peter Andersen, Claus Aagaard, Dennis Christensen, Morten Ruhwald, Thomas Lindenstrom, Olivier Neyrolles, Pierre Charneau, Christophe Guilhot, Antonio Peixoto, Martine Gilleron, Camille Locht, Roland Brosch, Genevieve Inchauspe, Stephane Leung Theung Long, Stefan Kaufmann, January Weiner, Jeroen Maertzdorf, Natalie Neuwenhuizen, Max Bastian, Steffen Stenger, Nadia Caccamo, Delia Goletti, Roberto Nisini, Sung Jae Shin, Hyejon Lee, Alex Sigal, Thomas Scriba, Gerhard Walzl, Andre Loxton, Robert Wilkinson, Pere-Joan Cardona, Cris Vilaplana, Carlos Martin, Dessi Marinova, Nacho Aguilo, François Spertini, Ruedi Aebersold, Etienne Caron, Daniel Pinschewer, Gennaro De Libero, Claire Anne Siegrist, Nicolas Collin, Christophe Barnier-Quer, Peter Sander, Frank Verreck, Tom Ottenhoff, Simone Joosten, Krista van Meijgaarden, Mariateresa Coppola, Annemieke Geluk, Nick Drager, Danielle Roordink, Jelle Thole, Yvonne Perrie, Marc Baird, Michael Levin, Hazel Dockrell, Steven Smith, Helen Fletcher, Gregory Bancroft, Ann Rawkins, Simon Clark, Mei Mei Ho, Helen McShane, Iman Satti, Elena Stylianou, Martin Vordermeier, Philip Hogarth
Published 2017-10-01