Adapting Blood DNA Methylation Aging Clocks for Use in Saliva Samples With Cell-type Deconvolution

by Fedor Galkin, Kirill Kochetov, Polina Mamoshina, Alex Zhavoronkov, Alex Zhavoronkov, Alex Zhavoronkov
Published 2021-07-01

Biomedical Progress Rates as New Parameters for Models of Economic Growth in Developed Countries

by Alex Zhavoronkov, Maria Litovchenko
Published 2013-11-01

Methods for structuring scientific knowledge from many areas related to aging research.

by Alex Zhavoronkov, Charles R Cantor
Published 2011-01-01

Machine Learning on Human Muscle Transcriptomic Data for Biomarker Discovery and Tissue-Specific Drug Target Identification

by Polina Mamoshina, Polina Mamoshina, Marina Volosnikova, Ivan V. Ozerov, Evgeny Putin, Evgeny Putin, Ekaterina Skibina, Franco Cortese, Alex Zhavoronkov, Alex Zhavoronkov, Alex Zhavoronkov
Published 2018-07-01

On Multilabel Classification Methods of Incompletely Labeled Biomedical Text Data

by Anton Kolesov, Dmitry Kamyshenkov, Maria Litovchenko, Elena Smekalova, Alexey Golovizin, Alex Zhavoronkov
Published 2014-01-01

Increased Pace of Aging in COVID-Related Mortality

by Fedor Galkin, Austin Parish, Evelyne Bischof, John Zhang, Polina Mamoshina, Alex Zhavoronkov
Published 2021-07-01

The Evaluation of Geroprotective Effects of Selected Flavonoids in Drosophila melanogaster and Caenorhabditis elegans

by Ekaterina Lashmanova, Nadezhda Zemskaya, Ekaterina Proshkina, Ekaterina Proshkina, Anna Kudryavtseva, Marina Volosnikova, Elena Marusich, Sergey Leonov, Alex Zhavoronkov, Alex Zhavoronkov, Alexey Moskalev, Alexey Moskalev, Alexey Moskalev, Alexey Moskalev
Published 2017-12-01

DNA Comet Giemsa Staining for Conventional Bright-Field Microscopy

by Andreyan Osipov, Ekaterina Arkhangelskaya, Alexei Vinokurov, Nadezhda Smetaninа, Alex Zhavoronkov, Dmitry Klokov
Published 2014-04-01

Human Gut Microbiome Aging Clock Based on Taxonomic Profiling and Deep Learning

by Fedor Galkin, Polina Mamoshina, Alex Aliper, Evgeny Putin, Vladimir Moskalev, Vadim N. Gladyshev, Alex Zhavoronkov
Published 2020-06-01

The potential of rapalogs to enhance resilience against SARS-CoV-2 infection and reduce the severity of COVID-19

by Evelyne Bischof, MD, Richard C Siow, PhD, Alex Zhavoronkov, PhD, Matt Kaeberlein, ProfPhD
Published 2021-02-01

The Neuronal Overexpression of Gclc in Drosophila melanogaster Induces Life Extension With Longevity-Associated Transcriptomic Changes in the Thorax

by Alexey Moskalev, Alexey Moskalev, Alexey Moskalev, Zulfiya Guvatova, Mikhail Shaposhnikov, Ekaterina Lashmanova, Ekaterina Proshkina, Liubov Koval, Alex Zhavoronkov, George Krasnov, Anna Kudryavtseva
Published 2019-03-01

Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma

by Jaime L. Chao, Michael Korzinkin, Alex Zhavoronkov, Ivan V. Ozerov, Matthew T. Walker, Kathleen Higgins, Mark W. Lingen, Evgeny Izumchenko, Peter A. Savage
Published 2021-09-01

Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy

by Rajani Ravi, Kimberly A. Noonan, Vui Pham, Rishi Bedi, Alex Zhavoronkov, Ivan V. Ozerov, Eugene Makarev, Artem V. Artemov, Piotr T. Wysocki, Ranee Mehra, Sridhar Nimmagadda, Luigi Marchionni, David Sidransky, Ivan M. Borrello, Evgeny Izumchenko, Atul Bedi
Published 2018-02-01

Doublecortin-Like Kinase 1 (DCLK1) Is a Novel NOTCH Pathway Signaling Regulator in Head and Neck Squamous Cell Carcinoma

by Esther C. Broner, Jonathan A. Trujillo, Michael Korzinkin, Tejaswini Subbannayya, Nishant Agrawal, Ivan V. Ozerov, Alex Zhavoronkov, Lisa Rooper, Nikita Kotlov, Le Shen, Alexander T. Pearson, Ari J. Rosenberg, Peter A. Savage, Vasudha Mishra, Aditi Chatterjee, Aditi Chatterjee, Aditi Chatterjee, David Sidransky, Evgeny Izumchenko
Published 2021-07-01

In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development

by Ivan V. Ozerov, Ksenia V. Lezhnina, Evgeny Izumchenko, Artem V. Artemov, Sergey Medintsev, Quentin Vanhaelen, Alexander Aliper, Jan Vijg, Andreyan N. Osipov, Ivan Labat, Michael D. West, Anton Buzdin, Charles R. Cantor, Yuri Nikolsky, Nikolay Borisov, Irina Irincheeva, Edward Khokhlovich, David Sidransky, Miguel Luiz Camargo, Alex Zhavoronkov
Published 2016-11-01

Molecular Sets (MOSES): A Benchmarking Platform for Molecular Generation Models

by Daniil Polykovskiy, Alexander Zhebrak, Benjamin Sanchez-Lengeling, Sergey Golovanov, Oktai Tatanov, Stanislav Belyaev, Rauf Kurbanov, Aleksey Artamonov, Vladimir Aladinskiy, Mark Veselov, Artur Kadurin, Simon Johansson, Hongming Chen, Sergey Nikolenko, Sergey Nikolenko, Sergey Nikolenko, Alán Aspuru-Guzik, Alán Aspuru-Guzik, Alán Aspuru-Guzik, Alán Aspuru-Guzik, Alex Zhavoronkov
Published 2020-12-01

COVIDomic: A multi-modal cloud-based platform for identification of risk factors associated with COVID-19 severity.

by Vladimir Naumov, Evgeny Putin, Stefan Pushkov, Ekaterina Kozlova, Konstantin Romantsov, Alexander Kalashnikov, Fedor Galkin, Nina Tihonova, Anastasia Shneyderman, Egor Galkin, Arsenii Zinkevich, Stephanie M Cope, Ramanathan Sethuraman, Tudor I Oprea, Alexander T Pearson, Savas Tay, Nishant Agrawal, Alexey Dubovenko, Quentin Vanhaelen, Ivan Ozerov, Alex Aliper, Evgeny Izumchenko, Alex Zhavoronkov
Published 2021-07-01

Identification of Novel Antibacterials Using Machine Learning Techniques

by Yan A. Ivanenkov, Yan A. Ivanenkov, Yan A. Ivanenkov, Yan A. Ivanenkov, Alex Zhavoronkov, Renat S. Yamidanov, Renat S. Yamidanov, Ilya A. Osterman, Ilya A. Osterman, Petr V. Sergiev, Petr V. Sergiev, Vladimir A. Aladinskiy, Vladimir A. Aladinskiy, Anastasia V. Aladinskaya, Anastasia V. Aladinskaya, Victor A. Terentiev, Victor A. Terentiev, Victor A. Terentiev, Mark S. Veselov, Mark S. Veselov, Mark S. Veselov, Andrey A. Ayginin, Andrey A. Ayginin, Victor G. Kartsev, Dmitry A. Skvortsov, Dmitry A. Skvortsov, Alexey V. Chemeris, Alexey Kh. Baimiev, Alina A. Sofronova, Alexander S. Malyshev, Gleb I. Filkov, Dmitry S. Bezrukov, Dmitry S. Bezrukov, Bogdan A. Zagribelnyy, Evgeny O. Putin, Maria M. Puchinina, Olga A. Dontsova, Olga A. Dontsova, Olga A. Dontsova
Published 2019-08-01