New Paradigm of Machine Learning (ML) in Personalized Oncology: Data Trimming for Squeezing More Biomarkers From Clinical Datasets

by Nicolas Borisov, Anton Buzdin, Anton Buzdin, Anton Buzdin
Published 2019-07-01

Human-Specific Endogenous Retroviruses

by Anton Buzdin
Published 2007-01-01

Editorial: Next Generation Sequencing Based Diagnostic Approaches in Clinical Oncology

by Anton Buzdin, Anton Buzdin, Anton Buzdin, Anton Buzdin, Ira Ida Skvortsova, Ira Ida Skvortsova, Ira Ida Skvortsova, Xinmin Li, Ye Wang
Published 2021-01-01

Algorithmic Annotation of Functional Roles for Components of 3,044 Human Molecular Pathways

by Maxim Sorokin, Maxim Sorokin, Maxim Sorokin, Nicolas Borisov, Nicolas Borisov, Denis Kuzmin, Alexander Gudkov, Marianna Zolotovskaia, Andrew Garazha, Anton Buzdin, Anton Buzdin, Anton Buzdin, Anton Buzdin
Published 2021-02-01

RNA Sequencing for Personalized Treatment of Metastatic Leiomyosarcoma: Case Report

by Alexander Seryakov, Zaynab Magomedova, Maria Suntsova, Anastasia Prokofieva, Elizaveta Rabushko, Alexander Glusker, Lyudmila Makovskaia, Marianna Zolotovskaia, Anton Buzdin, Anton Buzdin, Anton Buzdin, Anton Buzdin, Maxim Sorokin, Maxim Sorokin, Maxim Sorokin
Published 2021-08-01

Exploration of the Transcriptional Landscape of ALPPS Reveals the Pathways of Accelerated Liver Regeneration

by Pieter Borger, Marcel Schneider, Lukas Frick, Magda Langiewicz, Maksim Sorokin, Maksim Sorokin, Maksim Sorokin, Anton Buzdin, Anton Buzdin, Anton Buzdin, Anton Buzdin, Ekaterina Kachaylo, Rolf Graf, Bostjan Humar, Pierre-Alain Clavien
Published 2019-11-01

FLOating-Window Projective Separator (FloWPS): A Data Trimming Tool for Support Vector Machines (SVM) to Improve Robustness of the Classifier

by Victor Tkachev, Maxim Sorokin, Maxim Sorokin, Artem Mescheryakov, Alexander Simonov, Andrew Garazha, Anton Buzdin, Anton Buzdin, Anton Buzdin, Ilya Muchnik, Nicolas Borisov, Nicolas Borisov
Published 2019-01-01

RNA Sequencing Data for FFPE Tumor Blocks Can Be Used for Robust Estimation of Tumor Mutation Burden in Individual Biosamples

by Maxim Sorokin, Maxim Sorokin, Maxim Sorokin, Maxim Sorokin, Alexander Gorelyshev, Alexander Gorelyshev, Victor Efimov, Evgenia Zotova, Marianna Zolotovskaia, Elizaveta Rabushko, Denis Kuzmin, Alexander Seryakov, Dmitry Kamashev, Xinmin Li, Elena Poddubskaya, Maria Suntsova, Anton Buzdin, Anton Buzdin, Anton Buzdin, Anton Buzdin, Anton Buzdin
Published 2021-09-01

High-Throughput Mutation Data Now Complement Transcriptomic Profiling: Advances in Molecular Pathway Activation Analysis Approach in Cancer Biology

by Anton Buzdin, Maxim Sorokin, Elena Poddubskaya, Nicolas Borisov
Published 2019-03-01

FDA-Approved and Emerging Next Generation Predictive Biomarkers for Immune Checkpoint Inhibitors in Cancer Patients

by Ye Wang, Zhuang Tong, Wenhua Zhang, Weizhen Zhang, Anton Buzdin, Anton Buzdin, Anton Buzdin, Xiaofeng Mu, Xiaofeng Mu, Qing Yan, Xiaowen Zhao, Hui-Hua Chang, Mark Duhon, Xin Zhou, Gexin Zhao, Hong Chen, Xinmin Li
Published 2021-06-01

Cancer gene expression profiles associated with clinical outcomes to chemotherapy treatments

by Nicolas Borisov, Maxim Sorokin, Victor Tkachev, Andrew Garazha, Anton Buzdin
Published 2020-09-01

Flexible Data Trimming Improves Performance of Global Machine Learning Methods in Omics-Based Personalized Oncology

by Victor Tkachev, Maxim Sorokin, Constantin Borisov, Andrew Garazha, Anton Buzdin, Nicolas Borisov
Published 2020-01-01

Machine Learning Applicability for Classification of PAD/VCD Chemotherapy Response Using 53 Multiple Myeloma RNA Sequencing Profiles

by Nicolas Borisov, Anna Sergeeva, Maria Suntsova, Maria Suntsova, Mikhail Raevskiy, Nurshat Gaifullin, Larisa Mendeleeva, Alexander Gudkov, Maria Nareiko, Andrew Garazha, Andrew Garazha, Victor Tkachev, Victor Tkachev, Xinmin Li, Maxim Sorokin, Maxim Sorokin, Maxim Sorokin, Vadim Surin, Anton Buzdin, Anton Buzdin, Anton Buzdin
Published 2021-04-01

Reciprocal Dysregulation of MiR-146b and MiR-451 Contributes in Malignant Phenotype of Follicular Thyroid Tumor

by Margarita Knyazeva, Ekaterina Korobkina, Alexey Karizky, Maxim Sorokin, Anton Buzdin, Sergey Vorobyev, Anastasia Malek
Published 2020-08-01

Large-Scale Profiling of Signaling Pathways Reveals a Distinct Demarcation between Normal and Extended Liver Resection

by Pieter Borger, Anton Buzdin, Maksim Sorokin, Ekaterina Kachaylo, Bostjan Humar, Rolf Graf, Pierre-Alien Clavien
Published 2020-05-01

Shambhala: a platform-agnostic data harmonizer for gene expression data

by Nicolas Borisov, Irina Shabalina, Victor Tkachev, Maxim Sorokin, Andrew Garazha, Andrey Pulin, Ilya I. Eremin, Anton Buzdin
Published 2019-02-01

Retroelement-Linked H3K4me1 Histone Tags Uncover Regulatory Evolution Trends of Gene Enhancers and Feature Quickly Evolving Molecular Processes in Human Physiology

by Daniil Nikitin, Nikita Kolosov, Anastasiia Murzina, Karina Pats, Anton Zamyatin, Victor Tkachev, Maxim Sorokin, Philippe Kopylov, Anton Buzdin
Published 2019-10-01

Correction: Nikitin, D., et al. Retroelement—Linked Transcription Factor Binding Patterns Point to Quickly Developing Molecular Pathways in Human Evolution. <i>Cells</i> 2019, <i>8...

by Daniil Nikitin, Andrew Garazha, Maxim Sorokin, Dmitry Penzar, Victor Tkachev, Alexander Markov, Nurshat Gaifullin, Pieter Borger, Alexander Poltorak, Anton Buzdin
Published 2019-08-01

Retroelement—Linked Transcription Factor Binding Patterns Point to Quickly Developing Molecular Pathways in Human Evolution

by Daniil Nikitin, Andrew Garazha, Maxim Sorokin, Dmitry Penzar, Victor Tkachev, Alexander Markov, Nurshat Gaifullin, Pieter Borger, Alexander Poltorak, Anton Buzdin
Published 2019-02-01

RNA Sequencing in Comparison to Immunohistochemistry for Measuring Cancer Biomarkers in Breast Cancer and Lung Cancer Specimens

by Maxim Sorokin, Kirill Ignatev, Elena Poddubskaya, Uliana Vladimirova, Nurshat Gaifullin, Dmitriy Lantsov, Andrew Garazha, Daria Allina, Maria Suntsova, Victoria Barbara, Anton Buzdin
Published 2020-05-01