Vg1-Nodal heterodimers are the endogenous inducers of mesendoderm

by Tessa G Montague, Alexander F Schier
Published 2017-11-01

Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development

by Summer B. Thyme, Alexander F. Schier
Published 2016-04-01

Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish

by Guo-Liang Chew, Andrea Pauli, Alexander F. Schier
Published 2016-05-01

Individual long non-coding RNAs have no overt functions in zebrafish embryogenesis, viability and fertility

by Mehdi Goudarzi, Kathryn Berg, Lindsey M Pieper, Alexander F Schier
Published 2019-01-01

Attenuation of Notch and Hedgehog signaling is required for fate specification in the spinal cord.

by Peng Huang, Fengzhu Xiong, Sean G Megason, Alexander F Schier
Published 2012-01-01

Lefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptors.

by Simon K Cheng, Felix Olale, Ali H Brivanlou, Alexander F Schier
Published 2004-02-01

The pattern of nodal morphogen signaling is shaped by co-receptor expression

by Nathan D Lord, Adam N Carte, Philip B Abitua, Alexander F Schier
Published 2021-05-01

Internal guide RNA interactions interfere with Cas9-mediated cleavage

by Summer B. Thyme, Laila Akhmetova, Tessa G. Montague, Eivind Valen, Alexander F. Schier
Published 2016-06-01

Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish.

by Andrea Pauli, Tessa G Montague, Kim A Lennox, Mark A Behlke, Alexander F Schier
Published 2015-01-01

Response to Nodal morphogen gradient is determined by the kinetics of target gene induction

by Julien Dubrulle, Benjamin M Jordan, Laila Akhmetova, Jeffrey A Farrell, Seok-Hyung Kim, Lilianna Solnica-Krezel, Alexander F Schier
Published 2015-04-01

Efficient CRISPR-Cas9-Mediated Generation of Knockin Human Pluripotent Stem Cells Lacking Undesired Mutations at the Targeted Locus

by Florian T. Merkle, Werner M. Neuhausser, David Santos, Eivind Valen, James A. Gagnon, Kristi Maas, Jackson Sandoe, Alexander F. Schier, Kevin Eggan
Published 2015-05-01

Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling

by Megan L Norris, Andrea Pauli, James A Gagnon, Nathan D Lord, Katherine W Rogers, Christian Mosimann, Leonard I Zon, Alexander F Schier
Published 2017-11-01

Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs.

by James A Gagnon, Eivind Valen, Summer B Thyme, Peng Huang, Laila Akhmetova, Andrea Pauli, Tessa G Montague, Steven Zimmerman, Constance Richter, Alexander F Schier
Published 2014-01-01

Brain-wide mapping of neural activity controlling zebrafish exploratory locomotion

by Timothy W Dunn, Yu Mu, Sujatha Narayan, Owen Randlett, Eva A Naumann, Chao-Tsung Yang, Alexander F Schier, Jeremy Freeman, Florian Engert, Misha B Ahrens
Published 2016-03-01

Nodal patterning without Lefty inhibitory feedback is functional but fragile

by Katherine W Rogers, Nathan D Lord, James A Gagnon, Andrea Pauli, Steven Zimmerman, Deniz C Aksel, Deepak Reyon, Shengdar Q Tsai, J Keith Joung, Alexander F Schier
Published 2017-12-01

Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives

by Laina Freyer, Chih-Wei Hsu, Sonja Nowotschin, Andrea Pauli, Junji Ishida, Keiji Kuba, Akiyoshi Fukamizu, Alexander F. Schier, Pamela A. Hoodless, Mary E. Dickinson, Anna-Katerina Hadjantonakis
Published 2017-08-01