Slug-dependent upregulation of L1CAM is responsible for the increased invasion potential of pancreatic cancer cells following long-term 5-FU treatment.

by Kaja Lund, Jennifer L Dembinski, Nina Solberg, Alfonso Urbanucci, Ian G Mills, Stefan Krauss
Published 2015-01-01

Chromatin and Epigenetic Dysregulation of Prostate Cancer Development, Progression, and Therapeutic Response

by Konsta Kukkonen, Sinja Taavitsainen, Laura Huhtala, Joonas Uusi-Makela, Kirsi J. Granberg, Matti Nykter, Alfonso Urbanucci
Published 2021-07-01

Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer

by Verena Zuber, Francesco Bettella, Aree Witoelar, the PRACTICAL Consortium, the CRUK GWAS, the BCAC Consortium, the TRICL Consortium, Ole A. Andreassen, Ian G. Mills, Alfonso Urbanucci
Published 2017-03-01

The Quandary of DNA-Based Treatment Assessment in De Novo Metastatic Prostate Cancer in the Era of Precision Oncology

by Sigve Nakken, Wolfgang Lilleby, Marta D. Switlyk, Karen E. Knudsen, Oscar Lilleby, Sen Zhao, Fatemeh Kaveh, Per O. Ekstrøm, Alfonso Urbanucci, Eivind Hovig
Published 2021-04-01

Dysregulation of MITF Leads to Transformation in MC1R-Defective Melanocytes

by Timothy J. Lavelle, Tine Norman Alver, Karen-Marie Heintz, Patrik Wernhoff, Vegard Nygaard, Sigve Nakken, Geir Frode Øy, Sigurd Leinæs Bøe, Alfonso Urbanucci, Eivind Hovig
Published 2020-06-01

Gene Regulation Network Analysis on Human Prostate Orthografts Highlights a Potential Role for the <i>JMJD6</i> Regulon in Clinical Prostate Cancer

by Mario Cangiano, Magda Grudniewska, Mark J. Salji, Matti Nykter, Guido Jenster, Alfonso Urbanucci, Zoraide Granchi, Bart Janssen, Graham Hamilton, Hing Y. Leung, Inès J. Beumer
Published 2021-04-01

c-Myc Antagonises the Transcriptional Activity of the Androgen Receptor in Prostate Cancer Affecting Key Gene Networks

by Stefan J. Barfeld, Alfonso Urbanucci, Harri M. Itkonen, Ladan Fazli, Jessica L. Hicks, Bernd Thiede, Paul S. Rennie, Srinivasan Yegnasubramanian, Angelo M. DeMarzo, Ian G. Mills
Published 2017-04-01

Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer

by Alfonso Urbanucci, Stefan J. Barfeld, Ville Kytölä, Harri M. Itkonen, Ilsa M. Coleman, Daniel Vodák, Liisa Sjöblom, Xia Sheng, Teemu Tolonen, Sarah Minner, Christoph Burdelski, Kati K. Kivinummi, Annika Kohvakka, Steven Kregel, Mandeep Takhar, Mohammed Alshalalfa, Elai Davicioni, Nicholas Erho, Paul Lloyd, R. Jeffrey Karnes, Ashley E. Ross, Edward M. Schaeffer, Donald J. Vander Griend, Stefan Knapp, Eva Corey, Felix Y. Feng, Peter S. Nelson, Fahri Saatcioglu, Karen E. Knudsen, Teuvo L.J. Tammela, Guido Sauter, Thorsten Schlomm, Matti Nykter, Tapio Visakorpi, Ian G. Mills
Published 2017-06-01