Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

by Vander Heiden, Matthew G., Anastasiou, Dimitrios, Poulogiannis, George, Asara, John M., Boxer, Matthew B., Jiang, Jian-kang, Shen, Min, Gary, Bellinger, Sasaki, Atsuo T., Locasale, Jason W., Auld, Douglas S., Thomas, Craig J., Cantley, Lewis C., Bellinger, Gary
Published 2013

Systemic Elevation of PTEN Induces a Tumor-Suppressive Metabolic State

by Garcia-Cao, Isabel, Song, Min Sup, Hobbs, Robin M, Laurent, Gaelle, Giorgi, Carlotta, de Boer, Vincent C. J., Anastasiou, Dimitrios, Ito, Keisuke, Sasaki, Atsuo T, Rameh, Lucia, Carracedo, Arkaitz, Vander Heiden, Matthew G, Cantley, Lewis C., Pinton, Paolo, Haigis, Marcia C., Pandolfi, Pier Paolo, Vander Heiden, Matthew G.
Published 2014

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

by Locasale, Jason W., Grassian, Alexandra R., Melman, Tamar, Lyssiotis, Costas A., Mattaini, Katherine Ruth, Bass, Adam J., Heffron, Gregory J., Metallo, Christian M., Muranen, Taru, Sharfi, Hadar, Sasaki, Atsuo T., Anastasiou, Dimitrios, Mullarky, Edouard, Vokes, Natalie I., Sasaki, Mika, Beroukhim, Rameen, Stephanopoulos, Gregory, Ligon, Azra H., Meyerson, Matthew L., Richardson, Andrea L., Chin, Lynda, Wagner, Gerhard, Asara, John M., Brugge, Joan S., Cantley, Lewis C., Vander Heiden, Matthew G.
Published 2013