IGF1R Derived PI3K/AKT Signaling Maintains Growth in a Subset of Human T-Cell Acute Lymphoblastic Leukemias.

by Samuel Gusscott, Catherine E Jenkins, Sonya H Lam, Vincenzo Giambra, Michael Pollak, Andrew P Weng
Published 2016-01-01

Cell fate decisions in malignant hematopoiesis: leukemia phenotype is determined by distinct functional domains of the MN1 oncogene.

by Courteney K Lai, Yeonsook Moon, Florian Kuchenbauer, Daniel T Starzcynowski, Bob Argiropoulos, Eric Yung, Philip Beer, Adrian Schwarzer, Amit Sharma, Gyeongsin Park, Malina Leung, Grace Lin, Sarah Vollett, Stephen Fung, Connie J Eaves, Aly Karsan, Andrew P Weng, R Keith Humphries, Michael Heuser
Published 2014-01-01

Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia

by Manabu Kusakabe, Ann Chong Sun, Kateryna Tyshchenko, Rachel Wong, Aastha Nanda, Claire Shanna, Samuel Gusscott, Elizabeth A. Chavez, Alireza Lorzadeh, Alice Zhu, Ainsleigh Hill, Stacy Hung, Scott Brown, Artem Babaian, Xuehai Wang, Robert A. Holt, Christian Steidl, Aly Karsan, R. Keith Humphries, Connie J. Eaves, Martin Hirst, Andrew P. Weng
Published 2019-07-01

Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia.

by Gayle P Pouliot, James Degar, Laura Hinze, Bose Kochupurakkal, Chau D Vo, Melissa A Burns, Lisa Moreau, Chirag Ganesa, Justine Roderick, Sofie Peirs, Bjorn Menten, Mignon L Loh, Stephen P Hunger, Lewis B Silverman, Marian H Harris, Kristen E Stevenson, David M Weinstock, Andrew P Weng, Pieter Van Vlierberghe, Alan D D'Andrea, Alejandro Gutierrez
Published 2019-01-01