Oncogenic EGFR Represses the TET1 DNA Demethylase to Induce Silencing of Tumor Suppressors in Cancer Cells

by Matteo Forloni, Romi Gupta, Arvindhan Nagarajan, Li-Sha Sun, Yuying Dong, Valentina Pirazzoli, Maria Toki, Anna Wurtz, Mary Ann Melnick, Susumu Kobayashi, Robert J. Homer, David L. Rimm, Scott J. Gettinger, Katerina Politi, Shaillay Kumar Dogra, Narendra Wajapeyee
Published 2016-07-01

Acquired Resistance of EGFR-Mutant Lung Adenocarcinomas to Afatinib plus Cetuximab Is Associated with Activation of mTORC1

by Valentina Pirazzoli, Caroline Nebhan, Xiaoling Song, Anna Wurtz, Zenta Walther, Guoping Cai, Zhongming Zhao, Peilin Jia, Elisa de Stanchina, Erik M. Shapiro, Molly Gale, Ruonan Yin, Leora Horn, David P. Carbone, Philip J. Stephens, Vincent Miller, Scott Gettinger, William Pao, Katerina Politi
Published 2014-05-01