Dose-Dependent Mutation Rates Determine Optimum Erlotinib Dosing Strategies for EGFR Mutant Non-Small Cell Lung Cancer Patients.

by Lin L Liu, Fei Li, William Pao, Franziska Michor
Published 2015-01-01

Constitutive Activation of Raf-1 Induces Glioma Formation in Mice

by Yelena Lyustikman, Hiroyuki Momota, William Pao, Eric C. Holland
Published 2008-05-01

A MULTIPHASE FLOW LOOP DESIGN FOR INVESTIGATING THE PARTIAL PHASE SEPARATION IN A PIPE TEE

by Ahmed Saieed, Zeeshan Qadir Memon, Minh Cong Tran, William Pao King Soon
Published 2019-08-01

A review: Evolution of branching T-junction geometry in terms of diameter ratio, to improve phase separation

by Faheem Ejaz, William Pao, Mohammad Shakir Nasif, Ahmed Saieed, Zeeshan Q. Memon, Md Nuruzzaman
Published 2021-10-01

Induction of BIM is essential for apoptosis triggered by EGFR kinase inhibitors in mutant EGFR-dependent lung adenocarcinomas.

by Yixuan Gong, Romel Somwar, Katerina Politi, Marissa Balak, Juliann Chmielecki, Xuejun Jiang, William Pao
Published 2007-10-01

Influence of Sand Fines Transport Velocity on Erosion-Corrosion Phenomena of Carbon Steel 90-Degree Elbow

by Rehan Khan, Hamdan H. Ya, William Pao, Mohamad Zaki bin Abdullah, Faizul Azly Dzubir
Published 2020-05-01

Consensus rules in variant detection from next-generation sequencing data.

by Peilin Jia, Fei Li, Jufeng Xia, Haiquan Chen, Hongbin Ji, William Pao, Zhongming Zhao
Published 2012-01-01

The Impact of Microenvironmental Heterogeneity on the Evolution of Drug Resistance in Cancer Cells

by Shannon M. Mumenthaler, Jasmine Foo, Nathan C. Choi, Nicholas Heise, Kevin Leder, David B. Agus, William Pao, Franziska Michor, Parag Mallick
Published 2015-07-01

The Impact of Microenvironmental Heterogeneity on the Evolution of Drug Resistance in Cancer Cells

by Shannon M. Mumenthaler, Jasmine Foo, Nathan C. Choi, Nicholas Heise, Kevin Leder, David B. Agus, William Pao, Franziska Michor, Parag Mallick
Published 2015-01-01

Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain.

by William Pao, Vincent A Miller, Katerina A Politi, Gregory J Riely, Romel Somwar, Maureen F Zakowski, Mark G Kris, Harold Varmus
Published 2005-03-01

Effect of Sand Fines Concentration on the Erosion-Corrosion Mechanism of Carbon Steel 90° Elbow Pipe in Slug Flow

by Rehan Khan, Hamdan H. Ya, William Pao, Mohd Amin Abd Majid, Tauseef Ahmed, Amir Ahmad, Mohammad Azad Alam, M. Azeem, Hassan Iftikhar
Published 2020-10-01

Spectrum of oncogenic driver mutations in lung adenocarcinomas from East Asian never smokers.

by Chenguang Li, Rong Fang, Yihua Sun, Xiangkun Han, Fei Li, Bin Gao, A John Iafrate, Xin-Yuan Liu, William Pao, Haiquan Chen, Hongbin Ji
Published 2011-01-01

KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib.

by William Pao, Theresa Y Wang, Gregory J Riely, Vincent A Miller, Qiulu Pan, Marc Ladanyi, Maureen F Zakowski, Robert T Heelan, Mark G Kris, Harold E Varmus
Published 2005-01-01

Development of new mouse lung tumor models expressing EGFR T790M mutants associated with clinical resistance to kinase inhibitors.

by Lucia Regales, Marissa N Balak, Yixuan Gong, Katerina Politi, Ayana Sawai, Carl Le, Jason A Koutcher, David B Solit, Neal Rosen, Maureen F Zakowski, William Pao
Published 2007-08-01

High expression levels of total IGF-1R and sensitivity of NSCLC cells in vitro to an anti-IGF-1R antibody (R1507).

by Yixuan Gong, Evelyn Yao, Ronglai Shen, Aviva Goel, Maria Arcila, Julie Teruya-Feldstein, Maureen F Zakowski, Stanley Frankel, Martin Peifer, Roman K Thomas, Marc Ladanyi, William Pao
Published 2009-10-01

Rapamycin Prevents the Development and Progression of Mutant Epidermal Growth Factor Receptor Lung Tumors with the Acquired Resistance Mutation T790M

by Shigeru Kawabata, José R. Mercado-Matos, M. Christine Hollander, Danielle Donahue, Willie Wilson III, Lucia Regales, Mohit Butaney, William Pao, Kwok-Kin Wong, Pasi A. Jänne, Phillip A. Dennis
Published 2014-06-01

Acquired Resistance of EGFR-Mutant Lung Adenocarcinomas to Afatinib plus Cetuximab Is Associated with Activation of mTORC1

by Valentina Pirazzoli, Caroline Nebhan, Xiaoling Song, Anna Wurtz, Zenta Walther, Guoping Cai, Zhongming Zhao, Peilin Jia, Elisa de Stanchina, Erik M. Shapiro, Molly Gale, Ruonan Yin, Leora Horn, David P. Carbone, Philip J. Stephens, Vincent Miller, Scott Gettinger, William Pao, Katerina Politi
Published 2014-05-01

American Society of Clinical Oncology Clinical Practice Guideline Update on Chemotherapy for Stage IV Non–Small-Cell Lung Cancer

by Giuseppe GIACCONE, David TRENT, John R. STRAWN, Reily SMITH, Thomas J. SMITH, Joan H. SCHILLER, David G. PFISTER, Steven PIANTADOSI, Luke NORDQUIST, Daniel MILTON, Gregory MASTERS, Janessa L. LASKI, David H. JOHNSON, Julie BRAHMER, William PAO, Timothy ALIFF, Sarah TEMIN, Sherman Baker JR, Christopher G. AZZOLI
Published 2010-03-01

Routine multiplex mutational profiling of melanomas enables enrollment in genotype-driven therapeutic trials.

by Christine M Lovly, Kimberly Brown Dahlman, Laurel E Fohn, Zengliu Su, Dora Dias-Santagata, Donna J Hicks, Donald Hucks, Elizabeth Berry, Charles Terry, MarKeesa Duke, Yingjun Su, Tammy Sobolik-Delmaire, Ann Richmond, Mark C Kelley, Cindy L Vnencak-Jones, A John Iafrate, Jeffrey Sosman, William Pao
Published 2012-01-01

Mutational analysis of EGFR and related signaling pathway genes in lung adenocarcinomas identifies a novel somatic kinase domain mutation in FGFR4.

by Jenifer L Marks, Michael D McLellan, Maureen F Zakowski, Alex E Lash, Yumi Kasai, Stephen Broderick, Inderpal S Sarkaria, Duykhanh Pham, Bhuvanesh Singh, Tracie L Miner, Ginger A Fewell, Lucinda L Fulton, Elaine R Mardis, Richard K Wilson, Mark G Kris, Valerie W Rusch, Harold Varmus, William Pao
Published 2007-05-01