Leveraging Hypoxia-Activated Prodrugs to Prevent Drug Resistance in Solid Tumors.

by Danika Lindsay, Colleen M Garvey, Shannon M Mumenthaler, Jasmine Foo
Published 2016-08-01

PhysiCell: An open source physics-based cell simulator for 3-D multicellular systems.

by Ahmadreza Ghaffarizadeh, Randy Heiland, Samuel H Friedman, Shannon M Mumenthaler, Paul Macklin
Published 2018-02-01

Impact of tumor-parenchyma biomechanics on liver metastatic progression: a multi-model approach

by Yafei Wang, Erik Brodin, Kenichiro Nishii, Hermann B. Frieboes, Shannon M. Mumenthaler, Jessica L. Sparks, Paul Macklin
Published 2021-01-01

The Impact of Microenvironmental Heterogeneity on the Evolution of Drug Resistance in Cancer Cells

by Shannon M. Mumenthaler, Jasmine Foo, Nathan C. Choi, Nicholas Heise, Kevin Leder, David B. Agus, William Pao, Franziska Michor, Parag Mallick
Published 2015-07-01

The Impact of Microenvironmental Heterogeneity on the Evolution of Drug Resistance in Cancer Cells

by Shannon M. Mumenthaler, Jasmine Foo, Nathan C. Choi, Nicholas Heise, Kevin Leder, David B. Agus, William Pao, Franziska Michor, Parag Mallick
Published 2015-01-01

VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer

by Nikhil Baban Ghate, Sangnam Kim, Erin Spiller, Sungmin Kim, Yonghwan Shin, Suhn K. Rhie, Goar Smbatyan, Heinz‐Josef Lenz, Shannon M. Mumenthaler, Woojin An
Published 2021-10-01

Anti-EGFR Therapy Induces EGF Secretion by Cancer-Associated Fibroblasts to Confer Colorectal Cancer Chemoresistance

by Colleen M. Garvey, Roy Lau, Alyssa Sanchez, Ren X. Sun, Emma J. Fong, Michael E. Doche, Oscar Chen, Anthony Jusuf, Heinz-Josef Lenz, Brent Larson, Shannon M. Mumenthaler
Published 2020-05-01

Human colorectal cancer-on-chip model to study the microenvironmental influence on early metastatic spread

by Carly Strelez, Sujatha Chilakala, Kimya Ghaffarian, Roy Lau, Erin Spiller, Nolan Ung, Danielle Hixon, Ah Young Yoon, Ren X. Sun, Heinz-Josef Lenz, Jonathan E. Katz, Shannon M. Mumenthaler
Published 2021-05-01

Immunogenic cell death pathway polymorphisms for predicting oxaliplatin efficacy in metastatic colorectal cancer

by Chiara Cremolini, Fotios Loupakis, Alfredo Falcone, Francesca Battaglin, Heinz-Josef Lenz, Natsuko Kawanishi, Shivani Soni, Wu Zhang, Christoph Mancao, Bodour Salhia, Shannon M Mumenthaler, Daniel J Weisenberger, Gangning Liang, Joshua Millstein
Published 2020-07-01

Predictive Modeling of Drug Response in Non-Hodgkin's Lymphoma.

by Hermann B Frieboes, Bryan R Smith, Zhihui Wang, Masakatsu Kotsuma, Ken Ito, Armin Day, Benjamin Cahill, Colin Flinders, Shannon M Mumenthaler, Parag Mallick, Eman Simbawa, A S Al-Fhaid, S R Mahmoud, Sanjiv S Gambhir, Vittorio Cristini
Published 2015-01-01

A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice

by Christine Quach, Ying Song, Hongrui Guo, Shun Li, Hadi Maazi, Marshall Fung, Nathaniel Sands, Douglas O’Connell, Sara Restrepo-Vassalli, Billy Chai, Dali Nemecio, Vasu Punj, Omid Akbari, Gregory E. Idos, Shannon M. Mumenthaler, Nancy Wu, Sue Ellen Martin, Ashley Hagiya, James Hicks, Hengmin Cui, Chengyu Liang
Published 2019-12-01