Angiopoietin-like 4 promotes intracellular degradation of lipoprotein lipase in adipocytes

by Wieneke Dijk, Anne P. Beigneux, Mikael Larsson, André Bensadoun, Stephen G. Young, Sander Kersten
Published 2016-09-01

GPIHBP1, a GPI-anchored protein required for the lipolytic processing of triglyceride-rich lipoproteins

by Anne P. Beigneux, Brandon S.J. Davies, André Bensadoun, Loren G. Fong, Stephen G. Young
Published 2009-01-01

Agpat6 deficiency causes subdermal lipodystrophy and resistance to obesity

by Laurent Vergnes, Anne P. Beigneux, Ryan Davis, Steven M. Watkins, Stephen G. Young, Karen Reue
Published 2006-04-01

Apolipoprotein C-III inhibits triglyceride hydrolysis by GPIHBP1-bound LPL[S]

by Mikael Larsson, Christopher M. Allan, Rachel S. Jung, Patrick J. Heizer, Anne P. Beigneux, Stephen G. Young, Loren G. Fong
Published 2017-09-01

Mobility of “HSPG-bound” LPL explains how LPL is able to reach GPIHBP1 on capillaries

by Christopher M. Allan, Mikael Larsson, Rachel S. Jung, Michael Ploug, André Bensadoun, Anne P. Beigneux, Loren G. Fong, Stephen G. Young
Published 2017-01-01

Glycosylation of Asn-76 in mouse GPIHBP1 is critical for its appearance on the cell surface and the binding of chylomicrons and lipoprotein lipase

by Anne P. Beigneux, Peter Gin, Brandon S.J. Davies, Michael M. Weinstein, André Bensadoun, Robert O. Ryan, Loren G. Fong, Stephen G. Young
Published 2008-06-01

High-resolution imaging of dietary lipids in cells and tissues by NanoSIMS analysis[S]

by Haibo Jiang, Chris N. Goulbourne, Angelica Tatar, Kirsten Turlo, Daniel Wu, Anne P. Beigneux, Chris R.M. Grovenor, Loren G. Fong, Stephen G. Young
Published 2014-10-01

The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain

by Simon Mysling, Kristian Kølby Kristensen, Mikael Larsson, Anne P Beigneux, Henrik Gårdsvoll, Loren G Fong, André Bensadouen, Thomas JD Jørgensen, Stephen G Young, Michael Ploug
Published 2016-01-01

GPIHBP1, an endothelial cell transporter for lipoprotein lipase

by Stephen G. Young, Brandon S.J. Davies, Constance V. Voss, Peter Gin, Michael M. Weinstein, Peter Tontonoz, Karen Reue, André Bensadoun, Loren G. Fong, Anne P. Beigneux
Published 2011-11-01

Agpat6—a novel lipid biosynthetic gene required for triacylglycerol production in mammary epithelium

by Anne P. Beigneux, Laurent Vergnes, Xin Qiao, Steven Quatela, Ryan Davis, Steven M. Watkins, Rosalind A. Coleman, Rosemary L. Walzem, Mark Philips, Karen Reue, Stephen G. Young
Published 2006-04-01

Impaired thermogenesis and sharp increases in plasma triglyceride levels in GPIHBP1-deficient mice during cold exposure

by Mikael Larsson, Christopher M. Allan, Patrick J. Heizer, Yiping Tu, Norma P. Sandoval, Rachel S. Jung, Rosemary L. Walzem, Anne P. Beigneux, Stephen G. Young, Loren G. Fong
Published 2018-04-01

Chylomicronemia from GPIHBP1 autoantibodies

by Kazuya Miyashita, Jens Lutz, Lisa C. Hudgins, Dana Toib, Ambika P. Ashraf, Wenxin Song, Masami Murakami, Katsuyuki Nakajima, Michael Ploug, Loren G. Fong, Stephen G. Young, Anne P. Beigneux
Published 2020-11-01

Assessing mechanisms of GPIHBP1 and lipoprotein lipase movement across endothelial cells[S]

by Brandon S.J. Davies, Chris N. Goulbourne, Richard H. Barnes, II, Kirsten A. Turlo, Peter Gin, Sue Vaughan, David J. Vaux, André Bensadoun, Anne P. Beigneux, Loren G. Fong, Stephen G. Young
Published 2012-12-01

Mutation of conserved cysteines in the Ly6 domain of GPIHBP1 in familial chylomicronemia

by Gunilla Olivecrona, Ewa Ehrenborg, Henrik Semb, Elena Makoveichuk, Anna Lindberg, Michael R. Hayden, Peter Gin, Brandon S.J. Davies, Michael M. Weinstein, Loren G. Fong, Anne P. Beigneux, Stephen G. Young, Thomas Olivecrona, Olle Hernell
Published 2010-06-01

Mutating a conserved cysteine in GPIHBP1 reduces amounts of GPIHBP1 in capillaries and abolishes LPL binding

by Christopher M. Allan, Cris J. Jung, Mikael Larsson, Patrick J. Heizer, Yiping Tu, Norma P. Sandoval, Tiffany Ly P. Dang, Rachel S. Jung, Anne P. Beigneux, Pieter J. de Jong, Loren G. Fong, Stephen G. Young
Published 2017-07-01

An LPL–specific monoclonal antibody, 88B8, that abolishes the binding of LPL to GPIHBP1[S]

by Christopher M. Allan, Mikael Larsson, Xuchen Hu, Cuiwen He, Rachel S. Jung, Alaleh Mapar, Constance Voss, Kazuya Miyashita, Tetsuo Machida, Masami Murakami, Katsuyuki Nakajima, André Bensadoun, Michael Ploug, Loren G. Fong, Stephen G. Young, Anne P. Beigneux
Published 2016-10-01

An upstream enhancer regulates Gpihbp1 expression in a tissue-specific manner[S]

by Christopher M. Allan, Patrick J. Heizer, Yiping Tu, Norma P. Sandoval, Rachel S. Jung, Jazmin E. Morales, Eniko Sajti, Ty D. Troutman, Thomas L. Saunders, Darren A. Cusanovich, Anne P. Beigneux, Casey E. Romanoski, Loren G. Fong, Stephen G. Young
Published 2019-04-01

The structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase

by John G. Luz, Anne P. Beigneux, DeeAnn K. Asamoto, Cuiwen He, Wenxin Song, Christopher M. Allan, Jazmin Morales, Yiping Tu, Adam Kwok, Thomas Cottle, Muthuraman Meiyappan, Loren G. Fong, Judy E. Kim, Michael Ploug, Stephen G. Young, Gabriel Birrane
Published 2020-10-01

Monoclonal antibodies that bind to the Ly6 domain of GPIHBP1 abolish the binding of LPL

by Xuchen Hu, Mark W. Sleeman, Kazuya Miyashita, MacRae F. Linton, Christopher M. Allan, Cuiwen He, Mikael Larsson, Yiping Tu, Norma P. Sandoval, Rachel S. Jung, Alaleh Mapar, Tetsuo Machida, Masami Murakami, Katsuyuki Nakajima, Michael Ploug, Loren G. Fong, Stephen G. Young, Anne P. Beigneux
Published 2017-01-01

GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients

by Xuchen Hu, Ken Matsumoto, Rachel S Jung, Thomas A Weston, Patrick J Heizer, Cuiwen He, Norma P Sandoval, Christopher M Allan, Yiping Tu, Harry V Vinters, Linda M Liau, Rochelle M Ellison, Jazmin E Morales, Lynn J Baufeld, Nicholas A Bayley, Liqun He, Christer Betsholtz, Anne P Beigneux, David A Nathanson, Holger Gerhardt, Stephen G Young, Loren G Fong, Haibo Jiang
Published 2019-06-01