Combination therapy with BRAF and MEK inhibitors for melanoma: latest evidence and place in therapy

by Zeynep Eroglu, Antoni Ribas
Published 2016-01-01

429 Long-term analysis of MASTERKEY-265 phase 1b trial of talimogene laherparepvec (T-VEC) plus pembrolizumab in patients with unresectable stage IIIB-IVM1c melanoma

by Antoni Ribas, Olivier Michielin, Reinhard Dummer, Scott Diede, Salvador Martin-Algarra, Sheryl Treichel, Edward Chan
Published 2020-11-01

A kinetic investigation of interacting, stimulated T cells identifies conditions for rapid functional enhancement, minimal phenotype differentiation, and improved adoptive cell tra...

by Jing Zhou, Michael T Bethune, Natalia Malkova, Alexander M Sutherland, Begonya Comin-Anduix, Yapeng Su, David Baltimore, Antoni Ribas, James R Heath
Published 2018-01-01

Phenotypic heterogeneity and evolution of melanoma cells associated with targeted therapy resistance.

by Yapeng Su, Marcus Bintz, Yezi Yang, Lidia Robert, Alphonsus H C Ng, Victoria Liu, Antoni Ribas, James R Heath, Wei Wei
Published 2019-06-01

Phase II trial of sorafenib in combination with carboplatin and paclitaxel in patients with metastatic uveal melanoma: SWOG S0512.

by Shailender Bhatia, James Moon, Kim A Margolin, Jeffrey S Weber, Christopher D Lao, Megan Othus, Ana M Aparicio, Antoni Ribas, Vernon K Sondak
Published 2012-01-01

Impact of initial treatment and prognostic factors on postprogression survival in BRAF-mutated metastatic melanoma treated with dacarbazine or vemurafenib ± cobimetinib: a pooled a...

by Paolo A. Ascierto, Antoni Ribas, James Larkin, Grant A. McArthur, Karl D. Lewis, Axel Hauschild, Keith T. Flaherty, Edward McKenna, Qian Zhu, Yong Mun, Brigitte Dréno
Published 2020-08-01

Interleukin 32 expression in human melanoma

by Helicia Paz, Jennifer Tsoi, Anusha Kalbasi, Catherine S. Grasso, William H. McBride, Dörthe Schaue, Lisa H. Butterfield, Deena M. Maurer, Antoni Ribas, Thomas G. Graeber, James S. Economou
Published 2019-04-01

Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells

by Jiajun Du, Yapeng Su, Chenxi Qian, Dan Yuan, Kun Miao, Dongkwan Lee, Alphonsus H. C. Ng, Reto S. Wijker, Antoni Ribas, Raphael D. Levine, James R. Heath, Lu Wei
Published 2020-09-01

Reversing melanoma cross-resistance to BRAF and MEK inhibitors by co-targeting the AKT/mTOR pathway.

by Mohammad Atefi, Erika von Euw, Narsis Attar, Charles Ng, Connie Chu, Deliang Guo, Ramin Nazarian, Bartosz Chmielowski, John A Glaspy, Begonya Comin-Anduix, Paul S Mischel, Roger S Lo, Antoni Ribas
Published 2011-01-01

Modulation of cell signaling networks after CTLA4 blockade in patients with metastatic melanoma.

by Begoña Comin-Anduix, Hooman Sazegar, Thinle Chodon, Douglas Matsunaga, Jason Jalil, Erika von Euw, Helena Escuin-Ordinas, Robert Balderas, Bartosz Chmielowski, Jesus Gomez-Navarro, Richard C Koya, Antoni Ribas
Published 2010-09-01

Natural killer T cells in advanced melanoma patients treated with tremelimumab.

by F Javier Ibarrondo, Otto O Yang, Thinle Chodon, Earl Avramis, Yohan Lee, Hooman Sazegar, Jason Jalil, Bartosz Chmielowski, Richard C Koya, Ingrid Schmid, Jesus Gomez-Navarro, Beth D Jamieson, Antoni Ribas, Begoña Comin-Anduix
Published 2013-01-01

Human antigen-specific regulatory T cells generated by T cell receptor gene transfer.

by Todd M Brusko, Richard C Koya, Shirley Zhu, Michael R Lee, Amy L Putnam, Stephanie A McClymont, Michael I Nishimura, Shuhong Han, Lung-Ji Chang, Mark A Atkinson, Antoni Ribas, Jeffrey A Bluestone
Published 2010-07-01

Author Correction: PD-L1 blockade in combination with inhibition of MAPK oncogenic signaling in patients with advanced melanoma

by Antoni Ribas, Alain Algazi, Paolo A. Ascierto, Marcus O. Butler, Sunandana Chandra, Michael Gordon, Leonel Hernandez-Aya, Donald Lawrence, Jose Lutzky, Wilson H. Miller, Katie M. Campbell, Bruno Delafont, Shannon Marshall, Nancy Mueller, Caroline Robert
Published 2021-08-01

Wound healing with topical BRAF inhibitor therapy in a diabetic model suggests tissue regenerative effects.

by Helena Escuin-Ordinas, Yining Liu, Lu Sun, Willy Hugo, Robert Dimatteo, Rong Rong Huang, Paige Krystofinski, Ariel Azhdam, Jordan Lee, Begoña Comin-Anduix, Alistair J Cochran, Roger S Lo, Tatiana Segura, Philip O Scumpia, Antoni Ribas
Published 2021-01-01

IL-32γ potentiates tumor immunity in melanoma

by Thomas Gruber, Mirela Kremenovic, Hassan Sadozai, Nives Rombini, Lukas Baeriswyl, Fabienne Maibach, Robert L. Modlin, Michel Gilliet, Diego von Werdt, Robert E. Hunger, S. Morteza Seyed Jafari, Giulia Parisi, Gabriel Abril-Rodriguez, Antoni Ribas, Mirjam Schenk
Published 2020-09-01

PD-L1 blockade in combination with inhibition of MAPK oncogenic signaling in patients with advanced melanoma

by Antoni Ribas, Alain Algazi, Paolo A. Ascierto, Marcus O. Butler, Sunandana Chandra, Michael Gordon, Leonel Hernandez-Aya, Donald Lawrence, Jose Lutzky, Wilson H. Miller, Katie M. Campbell, Bruno Delafont, Shannon Marshall, Nancy Mueller, Caroline Robert
Published 2020-12-01

304 Intratumoral injection of CMP-001, a toll-like receptor 9 (TLR9) agonist, in combination with pembrolizumab reversed programmed death receptor 1 (PD-1) blockade resistance in a...

by Kim Margolin, Antoni Ribas, Riyue Bao, Adil Daud, Mohammed Milhem, Elizabeth Buchbinder, Geoffrey Gibney, Jason Luke, Takami Sato, David Mauro, Yousef Zakharia, Theresa Medina, John Kirkwood, Jiaxin Niu, Katie Campbell, George Weiner, Inderjit Mehmi, Heather Kelley, James Wooldridge
Published 2020-11-01

Genetic Heterogeneity of BRAF Fusion Kinases in Melanoma Affects Drug Responses

by Thomas Botton, Eric Talevich, Vivek Kumar Mishra, Tongwu Zhang, A. Hunter Shain, Céline Berquet, Alexander Gagnon, Robert L. Judson, Robert Ballotti, Antoni Ribas, Meenhard Herlyn, Stéphane Rocchi, Kevin M. Brown, Nicholas K. Hayward, Iwei Yeh, Boris C. Bastian
Published 2019-10-01

Evaluation of pre-analytical factors affecting plasma DNA analysis

by Havell Markus, Tania Contente-Cuomo, Maria Farooq, Winnie S. Liang, Mitesh J. Borad, Shivan Sivakumar, Simon Gollins, Nhan L. Tran, Harshil D. Dhruv, Michael E. Berens, Alan Bryce, Aleksandar Sekulic, Antoni Ribas, Jeffrey M. Trent, Patricia M. LoRusso, Muhammed Murtaza
Published 2018-05-01

Clinical features of serous retinopathy observed with cobimetinib in patients with BRAF-mutated melanoma treated in the randomized coBRIM study

by Luis de la Cruz-Merino, Lorenza Di Guardo, Jean-Jacques Grob, Alfredo Venosa, James Larkin, Grant A. McArthur, Antoni Ribas, Paolo A. Ascierto, Jeffrey T. R. Evans, Antonio Gomez-Escobar, Giulio Barteselli, Susan Eng, Jessie J. Hsu, Anne Uyei, Brigitte Dréno
Published 2017-06-01