Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor

by Abigail S. Krall, Shili Xu, Thomas G. Graeber, Daniel Braas, Heather R. Christofk
Published 2016-04-01

Phosphoproteomic analysis of platelets activated by pro-thrombotic oxidized phospholipids and thrombin.

by Alejandro Zimman, Bjoern Titz, Evangelia Komisopoulou, Sudipta Biswas, Thomas G Graeber, Eugene A Podrez
Published 2014-01-01

Precision oncology using a limited number of cells: optimization of whole genome amplification products for sequencing applications

by Shonan Sho, Colin M. Court, Paul Winograd, Sangjun Lee, Shuang Hou, Thomas G. Graeber, Hsian-Rong Tseng, James S. Tomlinson
Published 2017-07-01

Doxycycline alters metabolism and proliferation of human cell lines.

by Ethan Ahler, William J Sullivan, Ashley Cass, Daniel Braas, Autumn G York, Steven J Bensinger, Thomas G Graeber, Heather R Christofk
Published 2013-01-01

Determining PTEN functional status by network component deduced transcription factor activities.

by Linh M Tran, Chun-Ju Chang, Seema Plaisier, Shumin Wu, Julie Dang, Paul S Mischel, James C Liao, Thomas G Graeber, Hong Wu
Published 2012-01-01

A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers

by Shili Xu, Arthur Catapang, Daniel Braas, Linsey Stiles, Hanna M. Doh, Jason T. Lee, Thomas G. Graeber, Robert Damoiseaux, Orian Shirihai, Harvey R. Herschman
Published 2018-06-01

Intracellular C4BPA Levels Regulate NF-κB-Dependent Apoptosis

by Monica M. Olcina, Ryan K. Kim, Nikolas G. Balanis, Caiyun Grace Li, Rie von Eyben, Thomas G. Graeber, Daniel Ricklin, Manuel Stucki, Amato J. Giaccia
Published 2020-10-01

Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer

by Monica M. Olcina, Nikolas G. Balanis, Ryan K. Kim, B. Arman Aksoy, Julia Kodysh, Michael J. Thompson, Jeff Hammerbacher, Thomas G. Graeber, Amato J. Giaccia
Published 2018-12-01

Interleukin 32 expression in human melanoma

by Helicia Paz, Jennifer Tsoi, Anusha Kalbasi, Catherine S. Grasso, William H. McBride, Dörthe Schaue, Lisa H. Butterfield, Deena M. Maurer, Antoni Ribas, Thomas G. Graeber, James S. Economou
Published 2019-04-01

A Human Adult Stem Cell Signature Marks Aggressive Variants across Epithelial Cancers

by Bryan A. Smith, Nikolas G. Balanis, Avinash Nanjundiah, Katherine M. Sheu, Brandon L. Tsai, Qingfu Zhang, Jung Wook Park, Michael Thompson, Jiaoti Huang, Owen N. Witte, Thomas G. Graeber
Published 2018-09-01

Identification of small molecules that disrupt signaling between ABL and its positive regulator RIN1.

by Pamela Y Ting, Robert Damoiseaux, Björn Titz, Kenneth A Bradley, Thomas G Graeber, Virneliz Fernández-Vega, Thomas D Bannister, Peter Chase, Reji Nair, Louis Scampavia, Peter Hodder, Timothy P Spicer, John Colicelli
Published 2015-01-01

Defining the ATPome reveals cross-optimization of metabolic pathways

by Neal K. Bennett, Mai K. Nguyen, Maxwell A. Darch, Hiroki J. Nakaoka, Derek Cousineau, Johanna ten Hoeve, Thomas G. Graeber, Markus Schuelke, Emin Maltepe, Martin Kampmann, Bryce A. Mendelsohn, Jean L. Nakamura, Ken Nakamura
Published 2020-08-01

A metaproteomic approach to study human-microbial ecosystems at the mucosal luminal interface.

by Xiaoxiao Li, James LeBlanc, Allison Truong, Ravi Vuthoori, Sharon S Chen, Jonathan L Lustgarten, Bennett Roth, Jeff Allard, Andrew Ippoliti, Laura L Presley, James Borneman, William L Bigbee, Vanathi Gopalakrishnan, Thomas G Graeber, David Elashoff, Jonathan Braun, Lee Goodglick
Published 2011-01-01

Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities

by Matthew Garrett, Jantzen Sperry, Daniel Braas, Weihong Yan, Thuc M. Le, Jack Mottahedeh, Kirsten Ludwig, Ascia Eskin, Yue Qin, Rachelle Levy, Joshua J. Breunig, Frank Pajonk, Thomas G. Graeber, Caius G. Radu, Heather Christofk, Robert M. Prins, Albert Lai, Linda M. Liau, Giovanni Coppola, Harley I. Kornblum
Published 2018-04-01

Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression

by Angel Garcia-Diaz, Daniel Sanghoon Shin, Blanca Homet Moreno, Justin Saco, Helena Escuin-Ordinas, Gabriel Abril Rodriguez, Jesse M. Zaretsky, Lu Sun, Willy Hugo, Xiaoyan Wang, Giulia Parisi, Cristina Puig Saus, Davis Y. Torrejon, Thomas G. Graeber, Begonya Comin-Anduix, Siwen Hu-Lieskovan, Robert Damoiseaux, Roger S. Lo, Antoni Ribas
Published 2017-05-01

Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2–induced systemic toxicity

by Shen Li, Feiyang Ma, Tomohiro Yokota, Gustavo Garcia Jr., Amelia Palermo, Yijie Wang, Colin Farrell, Yu-Chen Wang, Rimao Wu, Zhiqiang Zhou, Calvin Pan, Marco Morselli, Michael A. Teitell, Sergey Ryazantsev, Gregory A. Fishbein, Johanna ten Hoeve, Valerie A. Arboleda, Joshua Bloom, Barbara Dillon, Matteo Pellegrini, Aldons J. Lusis, Thomas G. Graeber, Vaithilingaraja Arumugaswami, Arjun Deb
Published 2021-01-01

Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-fibrotic Small Molecule

by Preethi Vijayaraj, Aspram Minasyan, Abdo Durra, Saravanan Karumbayaram, Mehrsa Mehrabi, Cody J. Aros, Sarah D. Ahadome, David W. Shia, Katherine Chung, Jenna M. Sandlin, Kelly F. Darmawan, Kush V. Bhatt, Chase C. Manze, Manash K. Paul, Dan C. Wilkinson, Weihong Yan, Amander T. Clark, Tammy M. Rickabaugh, W. Dean Wallace, Thomas G. Graeber, Robert Damoiseaux, Brigitte N. Gomperts
Published 2019-12-01