CRISPulator: a discrete simulation tool for pooled genetic screens

by Tamas Nagy, Martin Kampmann
Published 2017-07-01

A high-throughput CRISPR interference screen for dissecting functional regulators of GPCR/cAMP signaling.

by Khairunnisa Mentari Semesta, Ruilin Tian, Martin Kampmann, Mark von Zastrow, Nikoleta G Tsvetanova
Published 2020-10-01

Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells

by Maxence Le Vasseur, Jonathan Friedman, Marco Jost, Jiawei Xu, Justin Yamada, Martin Kampmann, Max A Horlbeck, Michelle R Salemi, Brett S Phinney, Jonathan S Weissman, Jodi Nunnari
Published 2021-05-01

Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether

by Sandra Elizabeth Torres, Ciara M Gallagher, Lars Plate, Meghna Gupta, Christina R Liem, Xiaoyan Guo, Ruilin Tian, Robert M Stroud, Martin Kampmann, Jonathan S Weissman, Peter Walter
Published 2019-05-01

Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation

by Max A Horlbeck, Luke A Gilbert, Jacqueline E Villalta, Britt Adamson, Ryan A Pak, Yuwen Chen, Alexander P Fields, Chong Yon Park, Jacob E Corn, Martin Kampmann, Jonathan S Weissman
Published 2016-09-01

Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits

by Diego Acosta-Alvear, Min Y Cho, Thomas Wild, Tonia J Buchholz, Alana G Lerner, Olga Simakova, Jamie Hahn, Neha Korde, Ola Landgren, Irina Maric, Chunaram Choudhary, Peter Walter, Jonathan S Weissman, Martin Kampmann
Published 2015-09-01

A high-throughput screen of real-time ATP levels in individual cells reveals mechanisms of energy failure.

by Bryce A Mendelsohn, Neal K Bennett, Maxwell A Darch, Katharine Yu, Mai K Nguyen, Daniela Pucciarelli, Maxine Nelson, Max A Horlbeck, Luke A Gilbert, William Hyun, Martin Kampmann, Jean L Nakamura, Ken Nakamura
Published 2018-08-01

Defining the ATPome reveals cross-optimization of metabolic pathways

by Neal K. Bennett, Mai K. Nguyen, Maxwell A. Darch, Hiroki J. Nakaoka, Derek Cousineau, Johanna ten Hoeve, Thomas G. Graeber, Markus Schuelke, Emin Maltepe, Martin Kampmann, Bryce A. Mendelsohn, Jean L. Nakamura, Ken Nakamura
Published 2020-08-01

Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response

by Carmela Sidrauski, Jordan C Tsai, Martin Kampmann, Brian R Hearn, Punitha Vedantham, Priyadarshini Jaishankar, Masaaki Sokabe, Aaron S Mendez, Billy W Newton, Edward L Tang, Erik Verschueren, Jeffrey R Johnson, Nevan J Krogan, Christopher S Fraser, Jonathan S Weissman, Adam R Renslo, Peter Walter
Published 2015-04-01

A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies

by Celeste M. Karch, Aimee W. Kao, Anna Karydas, Khadijah Onanuga, Rita Martinez, Andrea Argouarch, Chao Wang, Cindy Huang, Peter Dongmin Sohn, Kathryn R. Bowles, Salvatore Spina, M. Catarina Silva, Jacob A. Marsh, Simon Hsu, Derian A. Pugh, Nupur Ghoshal, Joanne Norton, Yadong Huang, Suzee E. Lee, William W. Seeley, Panagiotis Theofilas, Lea T. Grinberg, Fermin Moreno, Kathryn McIlroy, Bradley F. Boeve, Nigel J. Cairns, John F. Crary, Stephen J. Haggarty, Justin K. Ichida, Kenneth S. Kosik, Bruce L. Miller, Li Gan, Alison M. Goate, Sally Temple, Carolina Alquezar, Kathryn Bowles, David Butler, John F. Crary, Li Gan, Alison M. Goate, Stephen J. Haggarty, Israel Hernandez, Valerie Hennes, Cindy Huang, Justin K. Ichida, Martin Kampmann, Aimee W. Kao, Celeste M. Karch, Anna Karydas, Kenneth S. Kosik, Rita Martinez, Khadijah Onanuga, M. Catarina Silva, Sally Temple, Chao Wang
Published 2019-11-01

Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance

by David Mavor, Kyle A. Barlow, Daniel Asarnow, Yuliya Birman, Derek Britain, Weilin Chen, Evan M. Green, Lillian R. Kenner, Bruk Mensa, Leanna S. Morinishi, Charlotte A. Nelson, Erin M. Poss, Pooja Suresh, Ruilin Tian, Taylor Arhar, Beatrice E. Ary, David P. Bauer, Ian D. Bergman, Rachel M. Brunetti, Cynthia M. Chio, Shizhong A. Dai, Miles S. Dickinson, Susanna K. Elledge, Cole V. M. Helsell, Nathan L. Hendel, Emily Kang, Nadja Kern, Matvei S. Khoroshkin, Lisa L. Kirkemo, Greyson R. Lewis, Kevin Lou, Wesley M. Marin, Alison M. Maxwell, Peter F. McTigue, Douglas Myers-Turnbull, Tamas L. Nagy, Andrew M. Natale, Keely Oltion, Sergei Pourmal, Gabriel K. Reder, Nicholas J. Rettko, Peter J. Rohweder, Daniel M. C Schwarz, Sophia K. Tan, Paul V. Thomas, Ryan W. Tibble, Jason P. Town, Mary K. Tsai, Fatima S. Ugur, Douglas R. Wassarman, Alexander M. Wolff, Taia S. Wu, Derek Bogdanoff, Jennifer Li, Kurt S. Thorn, Shane O'Conchúir, Danielle L. Swaney, Eric D. Chow, Hiten D. Madhani, Sy Redding, Daniel N. Bolon, Tanja Kortemme, Joseph L. DeRisi, Martin Kampmann, James S. Fraser
Published 2018-07-01