High-throughput validation of ceRNA regulatory networks

by Hua-Sheng Chiu, María Rodríguez Martínez, Mukesh Bansal, Aravind Subramanian, Todd R. Golub, Xuerui Yang, Pavel Sumazin, Andrea Califano
Published 2017-05-01

Evaluation of RNAi and CRISPR technologies by large-scale gene expression profiling in the Connectivity Map.

by Ian Smith, Peyton G Greenside, Ted Natoli, David L Lahr, David Wadden, Itay Tirosh, Rajiv Narayan, David E Root, Todd R Golub, Aravind Subramanian, John G Doench
Published 2017-11-01

Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling

by Mario Niepel, Marc Hafner, Qiaonan Duan, Zichen Wang, Evan O. Paull, Mirra Chung, Xiaodong Lu, Joshua M. Stuart, Todd R. Golub, Aravind Subramanian, Avi Ma’ayan, Peter K. Sorger
Published 2017-10-01

Advancing computational biology and bioinformatics research through open innovation competitions.

by Andrea Blasco, Michael G Endres, Rinat A Sergeev, Anup Jonchhe, N J Maximilian Macaluso, Rajiv Narayan, Ted Natoli, Jin H Paik, Bryan Briney, Chunlei Wu, Andrew I Su, Aravind Subramanian, Karim R Lakhani
Published 2019-01-01

Modulators of hepatic lipoprotein metabolism identified in a search for small-molecule inducers of tribbles pseudokinase 1 expression.

by Marek M Nagiec, Adam P Skepner, Joseph Negri, Michelle Eichhorn, Nicolas Kuperwasser, Eamon Comer, Giovanni Muncipinto, Aravind Subramanian, Clary Clish, Kiran Musunuru, Jeremy R Duvall, Michael Foley, Jose R Perez, Michelle A J Palmer
Published 2015-01-01

Whole‐blood dysregulation of actin‐cytoskeleton pathway in adult spinal muscular atrophy patients

by Jennifer J. Siranosian, Flavia C. Nery, Christiano R. R. Alves, Benjamin A. Siranosian, Nicholas J. Lyons, Eric J. Eichelberger, Reid Garner, Salomé Da Silva Duarte Lepez, Alec J. Johnstone, Aravind Subramanian, Kathryn J. Swoboda
Published 2020-07-01

Ferroptotic cell death triggered by conjugated linolenic acids is mediated by ACSL1

by Alexander Beatty, Tanu Singh, Yulia Y. Tyurina, Vladimir A. Tyurin, Svetlana Samovich, Emmanuelle Nicolas, Kristen Maslar, Yan Zhou, Kathy Q. Cai, Yinfei Tan, Sebastian Doll, Marcus Conrad, Aravind Subramanian, Hülya Bayır, Valerian E. Kagan, Ulrike Rennefahrt, Jeffrey R. Peterson
Published 2021-04-01

Drug and disease signature integration identifies synergistic combinations in glioblastoma

by Vasileios Stathias, Anna M. Jermakowicz, Marie E. Maloof, Michele Forlin, Winston Walters, Robert K. Suter, Michael A. Durante, Sion L. Williams, J. William Harbour, Claude-Henry Volmar, Nicholas J. Lyons, Claes Wahlestedt, Regina M. Graham, Michael E. Ivan, Ricardo J. Komotar, Jann N. Sarkaria, Aravind Subramanian, Todd R. Golub, Stephan C. Schürer, Nagi G. Ayad
Published 2018-12-01

A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery

by Emilie Crouchet, Simonetta Bandiera, Naoto Fujiwara, Shen Li, Hussein El Saghire, Mirian Fernández-Vaquero, Tobias Riedl, Xiaochen Sun, Hadassa Hirschfield, Frank Jühling, Shijia Zhu, Natascha Roehlen, Clara Ponsolles, Laura Heydmann, Antonio Saviano, Tongqi Qian, Anu Venkatesh, Joachim Lupberger, Eloi R. Verrier, Mozhdeh Sojoodi, Marine A. Oudot, François H. T. Duong, Ricard Masia, Lan Wei, Christine Thumann, Sarah C. Durand, Victor González-Motos, Danijela Heide, Jenny Hetzer, Shigeki Nakagawa, Atsushi Ono, Won-Min Song, Takaaki Higashi, Roberto Sanchez, Rosa S. Kim, C. Billie Bian, Karun Kiani, Tom Croonenborghs, Aravind Subramanian, Raymond T. Chung, Beate K. Straub, Detlef Schuppan, Maliki Ankavay, Laurence Cocquerel, Evelyne Schaeffer, Nicolas Goossens, Anna P. Koh, Milind Mahajan, Venugopalan D. Nair, Ganesh Gunasekaran, Myron E. Schwartz, Nabeel Bardeesy, Alex K. Shalek, Orit Rozenblatt-Rosen, Aviv Regev, Emanuele Felli, Patrick Pessaux, Kenneth K. Tanabe, Mathias Heikenwälder, Catherine Schuster, Nathalie Pochet, Mirjam B. Zeisel, Bryan C. Fuchs, Yujin Hoshida, Thomas F. Baumert
Published 2021-09-01