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Arthur Riggs (geneticist)

Arthur Dale Riggs (August 8, 1939 – March 23, 2022) was an American geneticist who worked with Genentech to express the first artificial gene in bacteria. His work was critical to the modern biotechnology industry because it was the first use of molecular techniques in commercial production of drugs and enabled the large-scale manufacturing of protein drugs, including insulin. He was also a major factor in the origin of epigenetics.

Riggs was a professor of biology and, in 2014, founding director of the Diabetes & Metabolism Research Institute of City of Hope National Medical Center. He was the founding dean of City of Hope's graduate school, the Irell & Manella Graduate School of Biological Sciences. He was also director emeritus of the Beckman Research Institute of City of Hope National Medical Center, which he headed from 2000 to 2007. Riggs served on the board of trustees at the Keck Graduate Institute of Applied Life Sciences. In 2006, Riggs was elected to the National Academy of Sciences. Provided by Wikipedia

1

A Simple and Cost-Effective Approach for In Vitro Production of Sliced siRNAs as Potent Triggers for RNAi

by Guihua Sun, Arthur D. Riggs
Published 2017-09-01

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2

Epigenetics and Evolution: Transposons and the Stochastic Epigenetic Modification Model

by Sergio Branciamore, Andrei S. Rodin, Grigoriy Gogoshin, Arthur D. Riggs
Published 2015-04-01

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3

SAIC: an iterative clustering approach for analysis of single cell RNA-seq data

by Lu Yang, Jiancheng Liu, Qiang Lu, Arthur D. Riggs, Xiwei Wu
Published 2017-10-01

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4

Small-Molecule-Based Lineage Reprogramming Creates Functional Astrocytes

by E Tian, Guoqiang Sun, Guihua Sun, Jianfei Chao, Peng Ye, Charles Warden, Arthur D. Riggs, Yanhong Shi
Published 2016-07-01

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5

Comparative transcriptomic analysis of SARS-CoV-2 infected cell model systems reveals differential innate immune responses

by Guihua Sun, Qi Cui, Gustavo Garcia, Cheng Wang, Mingzi Zhang, Vaithilingaraja Arumugaswami, Arthur D. Riggs, Yanhong Shi
Published 2021-08-01

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6

Mapping Human Pluripotent-to-Cardiomyocyte Differentiation: Methylomes, Transcriptomes, and Exon DNA Methylation “Memories”

by Joshua D. Tompkins, Marc Jung, Chang-yi Chen, Ziguang Lin, Jingjing Ye, Swetha Godatha, Elizabeth Lizhar, Xiwei Wu, David Hsu, Larry A. Couture, Arthur D. Riggs
Published 2016-02-01

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7

m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells

by Qi Cui, Hailing Shi, Peng Ye, Li Li, Qiuhao Qu, Guoqiang Sun, Guihua Sun, Zhike Lu, Yue Huang, Cai-Guang Yang, Arthur D. Riggs, Chuan He, Yanhong Shi
Published 2017-03-01

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8

IL-22-dependent dysbiosis and mononuclear phagocyte depletion contribute to steroid-resistant gut graft-versus-host disease in mice

by Qingxiao Song, Xiaoning Wang, Xiwei Wu, Tae Hyuk Kang, Hanjun Qin, Dongchang Zhao, Robert R. Jenq, Marcel R. M. van den Brink, Arthur D. Riggs, Paul J. Martin, Yuan-Zhong Chen, Defu Zeng
Published 2021-02-01

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9

The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model

by Kiyohito Murai, Guoqiang Sun, Peng Ye, E. Tian, Su Yang, Qi Cui, Guihua Sun, Daniel Trinh, Olivia Sun, Teresa Hong, Zhexing Wen, Markus Kalkum, Arthur D. Riggs, Hongjun Song, Guo-li Ming, Yanhong Shi
Published 2016-03-01

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10

Downregulation of TLX induces TET3 expression and inhibits glioblastoma stem cell self-renewal and tumorigenesis

by Qi Cui, Su Yang, Peng Ye, E. Tian, Guoqiang Sun, Jiehua Zhou, Guihua Sun, Xiaoxuan Liu, Chao Chen, Kiyohito Murai, Chunnian Zhao, Krist T. Azizian, Lu Yang, Charles Warden, Xiwei Wu, Massimo D'Apuzzo, Christine Brown, Behnam Badie, Ling Peng, Arthur D. Riggs, John J. Rossi, Yanhong Shi
Published 2016-02-01

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