Synaptic Dysfunction in Prion Diseases: A Trafficking Problem?

by Assunta Senatore, Elena Restelli, Roberto Chiesa
Published 2013-01-01

The biological function of the cellular prion protein: an update

by Marie-Angela Wulf, Assunta Senatore, Adriano Aguzzi
Published 2017-05-01

Neurotoxic Antibodies against the Prion Protein Do Not Trigger Prion Replication.

by Karl Frontzek, Manuela Pfammatter, Silvia Sorce, Assunta Senatore, Petra Schwarz, Rita Moos, Katrin Frauenknecht, Simone Hornemann, Adriano Aguzzi
Published 2016-01-01

Soluble dimeric prion protein ligand activates Adgrg6 receptor but does not rescue early signs of demyelination in PrP-deficient mice.

by Anna Henzi, Assunta Senatore, Asvin K K Lakkaraju, Claudia Scheckel, Jonas Mühle, Regina Reimann, Silvia Sorce, Gebhard Schertler, Klaus V Toyka, Adriano Aguzzi
Published 2020-01-01

Inhibition of group-I metabotropic glutamate receptors protects against prion toxicity.

by Despoina Goniotaki, Asvin K K Lakkaraju, Amulya N Shrivastava, Pamela Bakirci, Silvia Sorce, Assunta Senatore, Rajlakshmi Marpakwar, Simone Hornemann, Fabrizio Gasparini, Antoine Triller, Adriano Aguzzi
Published 2017-11-01

The ultrastructure of infectious L-type bovine spongiform encephalopathy prions constrains molecular models.

by Razieh Kamali-Jamil, Ester Vázquez-Fernández, Brian Tancowny, Vineet Rathod, Sara Amidian, Xiongyao Wang, Xinli Tang, Andrew Fang, Assunta Senatore, Simone Hornemann, Sandor Dudas, Adriano Aguzzi, Howard S Young, Holger Wille
Published 2021-06-01

Protective anti‐prion antibodies in human immunoglobulin repertoires

by Assunta Senatore, Karl Frontzek, Marc Emmenegger, Andra Chincisan, Marco Losa, Regina Reimann, Geraldine Horny, Jingjing Guo, Sylvie Fels, Silvia Sorce, Caihong Zhu, Nathalie George, Stefan Ewert, Thomas Pietzonka, Simone Hornemann, Adriano Aguzzi
Published 2020-09-01

PHACTR1 genetic variability is not critical in small vessel ischemic disease patients and PcomA recruitment in C57BL/6J mice

by Clemens Messerschmidt, Marco Foddis, Sonja Blumenau, Susanne Müller, Kajetan Bentele, Manuel Holtgrewe, Celia Kun-Rodrigues, Isabel Alonso, Maria do Carmo Macario, Ana Sofia Morgadinho, Ana Graça Velon, Gustavo Santo, Isabel Santana, Saana Mönkäre, Liina Kuuluvainen, Johanna Schleutker, Minna Pöyhönen, Liisa Myllykangas, Assunta Senatore, Daniel Berchtold, Katarzyna Winek, Andreas Meisel, Aleksandra Pavlovic, Vladimir Kostic, Valerija Dobricic, Ebba Lohmann, Hasmet Hanagasi, Gamze Guven, Basar Bilgic, Jose Bras, Rita Guerreiro, Dieter Beule, Ulrich Dirnagl, Celeste Sassi
Published 2021-03-01