SCelVis: exploratory single cell data analysis on the desktop and in the cloud

by Benedikt Obermayer, Manuel Holtgrewe, Mikko Nieminen, Clemens Messerschmidt, Dieter Beule
Published 2020-02-01

SigsPack, a package for cancer mutational signatures

by Franziska Schumann, Eric Blanc, Clemens Messerschmidt, Thomas Blankenstein, Antonia Busse, Dieter Beule
Published 2019-09-01

Identification and ranking of recurrent neo-epitopes in cancer

by Eric Blanc, Manuel Holtgrewe, Arunraj Dhamodaran, Clemens Messerschmidt, Gerald Willimsky, Thomas Blankenstein, Dieter Beule
Published 2019-11-01

Dataset for: Modeling chemotherapy induced neurotoxicity with human induced pluripotent stem cell (iPSC)-derived sensory neurons

by Christian Schinke, Valeria Fernandez Vallone, Andranik Ivanov, Yangfan Peng, Péter Körtvelyessy, Luca Nolte, Petra Huehnchen, Dieter Beule, Harald Stachelscheid, Wolfgang Boehmerle, Matthias Endres
Published 2021-10-01

Modeling chemotherapy induced neurotoxicity with human induced pluripotent stem cell (iPSC) -derived sensory neurons

by Christian Schinke, Valeria Fernandez Vallone, Andranik Ivanov, Yangfan Peng, Péter Körtvelyessy, Luca Nolte, Petra Huehnchen, Dieter Beule, Harald Stachelscheid, Wolfgang Boehmerle, Matthias Endres
Published 2021-07-01

Enzymatic Dissociation Induces Transcriptional and Proteotype Bias in Brain Cell Populations

by Daniele Mattei, Andranik Ivanov, Marc van van Oostrum, Stanislav Pantelyushin, Juliet Richetto, Flavia Mueller, Michal Beffinger, Linda Schellhammer, Johannes vom vom Berg, Bernd Wollscheid, Dieter Beule, Rosa Chiara Paolicelli, Urs Meyer
Published 2020-10-01

Generation and characterization of a mitotane-resistant adrenocortical cell line

by Eric Seidel, Gudrun Walenda, Clemens Messerschmidt, Benedikt Obermayer, Mirko Peitzsch, Paal Wallace, Rohini Bahethi, Taekyeong Yoo, Murim Choi, Petra Schrade, Sebastian Bachmann, Gerhard Liebisch, Graeme Eisenhofer, Dieter Beule, Ute I Scholl
Published 2020-02-01

WiPP: Workflow for Improved Peak Picking for Gas Chromatography-Mass Spectrometry (GC-MS) Data

by Nico Borgsmüller, Yoann Gloaguen, Tobias Opialla, Eric Blanc, Emilie Sicard, Anne-Lise Royer, Bruno Le Bizec, Stéphanie Durand, Carole Migné, Mélanie Pétéra, Estelle Pujos-Guillot, Franck Giacomoni, Yann Guitton, Dieter Beule, Jennifer Kirwan
Published 2019-08-01

Acquired resistance to DZNep-mediated apoptosis is associated with copy number gains of AHCY in a B-cell lymphoma model

by Chidimma Agatha Akpa, Karsten Kleo, Elisabeth Oker, Nancy Tomaszewski, Clemens Messerschmidt, Cristina López, Rabea Wagener, Kathrin Oehl-Huber, Katja Dettmer, Anne Schoeler, Dido Lenze, Peter J. Oefner, Dieter Beule, Reiner Siebert, David Capper, Lora Dimitrova, Michael Hummel
Published 2020-05-01

Transcriptional and Translational Differences of Microglia from Male and Female Brains

by Dilansu Guneykaya, Andranik Ivanov, Daniel Perez Hernandez, Verena Haage, Bartosz Wojtas, Niklas Meyer, Meron Maricos, Philipp Jordan, Alice Buonfiglioli, Bartlomiej Gielniewski, Natalia Ochocka, Cagla Cömert, Corinna Friedrich, Lorena Suarez Artiles, Bozena Kaminska, Philipp Mertins, Dieter Beule, Helmut Kettenmann, Susanne A. Wolf
Published 2018-09-01

let-7 MicroRNAs Regulate Microglial Function and Suppress Glioma Growth through Toll-Like Receptor 7

by Alice Buonfiglioli, Ibrahim E. Efe, Dilansu Guneykaya, Andranik Ivanov, Yimin Huang, Elisabeth Orlowski, Christina Krüger, Rudolf A. Deisz, Darko Markovic, Charlotte Flüh, Andrew G. Newman, Ulf C. Schneider, Dieter Beule, Susanne A. Wolf, Omar Dzaye, David H. Gutmann, Marcus Semtner, Helmut Kettenmann, Seija Lehnardt
Published 2019-12-01

Adipose tissue ATGL modifies the cardiac lipidome in pressure-overload-induced left ventricular failure.

by Janek Salatzki, Anna Foryst-Ludwig, Kajetan Bentele, Annelie Blumrich, Elia Smeir, Zsofia Ban, Sarah Brix, Jana Grune, Niklas Beyhoff, Robert Klopfleisch, Sebastian Dunst, Michal A Surma, Christian Klose, Michael Rothe, Frank R Heinzel, Alexander Krannich, Erin E Kershaw, Dieter Beule, P Christian Schulze, Nikolaus Marx, Ulrich Kintscher
Published 2018-01-01

Mitogen‐activated protein kinase activity drives cell trajectories in colorectal cancer

by Florian Uhlitz, Philip Bischoff, Stefan Peidli, Anja Sieber, Alexandra Trinks, Mareen Lüthen, Benedikt Obermayer, Eric Blanc, Yana Ruchiy, Thomas Sell, Soulafa Mamlouk, Roberto Arsie, Tzu‐Ting Wei, Kathleen Klotz‐Noack, Roland F Schwarz, Birgit Sawitzki, Carsten Kamphues, Dieter Beule, Markus Landthaler, Christine Sers, David Horst, Nils Blüthgen, Markus Morkel
Published 2021-10-01

Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19

by Geraldine Nouailles, Emanuel Wyler, Peter Pennitz, Dylan Postmus, Daria Vladimirova, Julia Kazmierski, Fabian Pott, Kristina Dietert, Michael Muelleder, Vadim Farztdinov, Benedikt Obermayer, Sandra-Maria Wienhold, Sandro Andreotti, Thomas Hoefler, Birgit Sawitzki, Christian Drosten, Leif E. Sander, Norbert Suttorp, Markus Ralser, Dieter Beule, Achim D. Gruber, Christine Goffinet, Markus Landthaler, Jakob Trimpert, Martin Witzenrath
Published 2021-08-01

DNA copy number changes define spatial patterns of heterogeneity in colorectal cancer

by Soulafa Mamlouk, Liam Harold Childs, Daniela Aust, Daniel Heim, Friederike Melching, Cristiano Oliveira, Thomas Wolf, Pawel Durek, Dirk Schumacher, Hendrik Bläker, Moritz von Winterfeld, Bastian Gastl, Kerstin Möhr, Andrea Menne, Silke Zeugner, Torben Redmer, Dido Lenze, Sascha Tierling, Markus Möbs, Wilko Weichert, Gunnar Folprecht, Eric Blanc, Dieter Beule, Reinhold Schäfer, Markus Morkel, Frederick Klauschen, Ulf Leser, Christine Sers
Published 2017-01-01

PHACTR1 genetic variability is not critical in small vessel ischemic disease patients and PcomA recruitment in C57BL/6J mice

by Clemens Messerschmidt, Marco Foddis, Sonja Blumenau, Susanne Müller, Kajetan Bentele, Manuel Holtgrewe, Celia Kun-Rodrigues, Isabel Alonso, Maria do Carmo Macario, Ana Sofia Morgadinho, Ana Graça Velon, Gustavo Santo, Isabel Santana, Saana Mönkäre, Liina Kuuluvainen, Johanna Schleutker, Minna Pöyhönen, Liisa Myllykangas, Assunta Senatore, Daniel Berchtold, Katarzyna Winek, Andreas Meisel, Aleksandra Pavlovic, Vladimir Kostic, Valerija Dobricic, Ebba Lohmann, Hasmet Hanagasi, Gamze Guven, Basar Bilgic, Jose Bras, Rita Guerreiro, Dieter Beule, Ulrich Dirnagl, Celeste Sassi
Published 2021-03-01