Characterization of the Methylthioadenosine Phosphorylase Polymorphism rs7023954 - Incidence and Effects on Enzymatic Function in Malignant Melanoma.

by Katharina Limm, Katja Dettmer, Jörg Reinders, Peter J Oefner, Anja-Katrin Bosserhoff
Published 2016-01-01

Optimized Protocol for the In Situ Derivatization of Glutathione with <i>N</i>-Ethylmaleimide in Cultured Cells and the Simultaneous Determination of Glutathione/Glutathione Disulf...

by Xueni Sun, Raffaela S. Berger, Paul Heinrich, Ibtissam Marchiq, Jacques Pouyssegur, Kathrin Renner, Peter J. Oefner, Katja Dettmer
Published 2020-07-01

Serotonin and tryptophan metabolites, autoantibodies and gut microbiome in APECED

by Emmi Naskali, Katja Dettmer, Peter J Oefner, Pedro A B Pereira, Kai Krohn, Petri Auvinen, Annamari Ranki, Nicolas Kluger
Published 2019-01-01

Biological and clinical significance of tryptophan-catabolizing enzymes in cutaneous T-cell lymphomas

by Pilvi Maliniemi, Kirsi Laukkanen, Liisa Väkevä, Katja Dettmer, Tuomas Lipsanen, Leila Jeskanen, Alban Bessede, Peter J. Oefner, Marshall E. Kadin, Annamari Ranki
Published 2017-03-01

Cold Atmospheric Plasma Changes the Amino Acid Composition of Solutions and Influences the Anti-Tumor Effect on Melanoma Cells

by Stephanie Arndt, Fadi Fadil, Katja Dettmer, Petra Unger, Marko Boskovic, Claudia Samol, Anja-Katrin Bosserhoff, Julia L. Zimmermann, Michael Gruber, Wolfram Gronwald, Sigrid Karrer
Published 2021-07-01

Combined Modulation of Tumor Metabolism by Metformin and Diclofenac in Glioma

by Valeria Gerthofer, Marina Kreutz, Kathrin Renner, Birgit Jachnik, Katja Dettmer, Peter Oefner, Markus J. Riemenschneider, Martin Proescholdt, Arabel Vollmann-Zwerenz, Peter Hau, Corinna Seliger
Published 2018-08-01

Antithymocyte Globulin Induces a Tolerogenic Phenotype in Human Dendritic Cells

by Tobias Roider, Michael Katzfuß, Carina Matos, Katrin Singer, Kathrin Renner, Peter J. Oefner, Katja Dettmer-Wilde, Wolfgang Herr, Ernst Holler, Marina Kreutz, Katrin Peter
Published 2016-12-01

D-2-hydroxyglutarate interferes with HIF-1α stability skewing T-cell metabolism towards oxidative phosphorylation and impairing Th17 polarization

by Martin Böttcher, Kathrin Renner, Raffaela Berger, Kristin Mentz, Simone Thomas, Zugey Elizabeth Cardenas-Conejo, Katja Dettmer, Peter J. Oefner, Andreas Mackensen, Marina Kreutz, Dimitrios Mougiakakos
Published 2018-07-01

Expression and function of methylthioadenosine phosphorylase in chronic liver disease.

by Barbara Czech, Katja Dettmer, Daniela Valletta, Michael Saugspier, Andreas Koch, Axel P Stevens, Wolfgang E Thasler, Martina Müller, Peter J Oefner, Anja-Katrin Bosserhoff, Claus Hellerbrand
Published 2013-01-01

D-2-Hydroxyglutarate and L-2-Hydroxyglutarate Inhibit IL-12 Secretion by Human Monocyte-Derived Dendritic Cells

by Ines Ugele, Zugey Elizabeth Cárdenas-Conejo, Kathrin Hammon, Monika Wehrstein, Christina Bruss, Katrin Peter, Katrin Singer, Eva Gottfried, Jakob Boesch, Peter Oefner, Katja Dettmer, Kathrin Renner, Marina Kreutz
Published 2019-02-01

Limitation of TCA Cycle Intermediates Represents an Oxygen-Independent Nutritional Antibacterial Effector Mechanism of Macrophages

by Inaya Hayek, Fabian Fischer, Jan Schulze-Luehrmann, Katja Dettmer, Katharina Sobotta, Valentin Schatz, Lisa Kohl, Katharina Boden, Roland Lang, Peter J. Oefner, Stefan Wirtz, Jonathan Jantsch, Anja Lührmann
Published 2019-03-01

Renal Fanconi Syndrome Is Caused by a Mistargeting-Based Mitochondriopathy

by Nadine Assmann, Katja Dettmer, Johann M.B. Simbuerger, Carsten Broeker, Nadine Nuernberger, Kathrin Renner, Holly Courtneidge, Enriko D. Klootwijk, Axel Duerkop, Andrew Hall, Robert Kleta, Peter J. Oefner, Markus Reichold, Joerg Reinders
Published 2016-05-01

Topical Diclofenac Reprograms Metabolism and Immune Cell Infiltration in Actinic Keratosis

by Katrin Singer, Katja Dettmer, Petra Unger, Gabriele Schönhammer, Kathrin Renner, Kathrin Renner, Katrin Peter, Peter J. Siska, Mark Berneburg, Wolfgang Herr, Peter J. Oefner, Sigrid Karrer, Marina Kreutz, Marina Kreutz, Elisabeth Datz
Published 2019-07-01

Lactonization of the Oncometabolite D-2-Hydroxyglutarate Produces a Novel Endogenous Metabolite

by Raffaela S. Berger, Christian J. Wachsmuth, Magdalena C. Waldhier, Kathrin Renner-Sattler, Simone Thomas, Anuhar Chaturvedi, Hans-Helmut Niller, Elisabeth Bumes, Peter Hau, Martin Proescholdt, Wolfram Gronwald, Michael Heuser, Marina Kreutz, Peter J. Oefner, Katja Dettmer
Published 2021-04-01

New aspects of an old drug--diclofenac targets MYC and glucose metabolism in tumor cells.

by Eva Gottfried, Sven A Lang, Kathrin Renner, Anja Bosserhoff, Wolfram Gronwald, Michael Rehli, Sabine Einhell, Isabel Gedig, Katrin Singer, Anton Seilbeck, Andreas Mackensen, Oliver Grauer, Peter Hau, Katja Dettmer, Reinhard Andreesen, Peter J Oefner, Marina Kreutz
Published 2013-01-01

Acquired resistance to DZNep-mediated apoptosis is associated with copy number gains of AHCY in a B-cell lymphoma model

by Chidimma Agatha Akpa, Karsten Kleo, Elisabeth Oker, Nancy Tomaszewski, Clemens Messerschmidt, Cristina López, Rabea Wagener, Kathrin Oehl-Huber, Katja Dettmer, Anne Schoeler, Dido Lenze, Peter J. Oefner, Dieter Beule, Reiner Siebert, David Capper, Lora Dimitrova, Michael Hummel
Published 2020-05-01

Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice

by Róisín M. Loftus, Nadine Assmann, Nidhi Kedia-Mehta, Katie L. O’Brien, Arianne Garcia, Conor Gillespie, Jens L. Hukelmann, Peter J. Oefner, Angus I. Lamond, Clair M. Gardiner, Katja Dettmer, Doreen A. Cantrell, Linda V. Sinclair, David K. Finlay
Published 2018-06-01

Activation of Epidermal Growth Factor Receptor Sensitizes Glioblastoma Cells to Hypoxia-Induced Cell Death

by Anna-Luisa Luger, Nadja I. Lorenz, Hans Urban, Iris Divé, Anna L. Engel, Florian Strassheimer, Katja Dettmer, Pia S. Zeiner, Shabnam Shaid, Nina Struve, Malte Kriegs, Ute Hofmann, Peter J. Oefner, Patrick N. Harter, Joachim P. Steinbach, Michael W. Ronellenfitsch
Published 2020-08-01

Cooperative STAT/NF-κB signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression

by Maren Feist, Philipp Schwarzfischer, Paul Heinrich, Xueni Sun, Judith Kemper, Frederike von Bonin, Paula Perez-Rubio, Franziska Taruttis, Thorsten Rehberg, Katja Dettmer, Wolfram Gronwald, Jörg Reinders, Julia C. Engelmann, Jan Dudek, Wolfram Klapper, Lorenz Trümper, Rainer Spang, Peter J. Oefner, Dieter Kube
Published 2018-04-01

High CD206 levels in Hodgkin lymphoma‐educated macrophages are linked to matrix‐remodeling and lymphoma dissemination

by Annekatrin Arlt, Frederike vonBonin, Thorsten Rehberg, Paula Perez‐Rubio, Julia C. Engelmann, Katharina Limm, Sarah Reinke, Christian Dullin, Xueni Sun, Rieke Specht, Markus Maulhardt, Franziska Linke, Gertrude Bunt, Wolfram Klapper, Martina Vockerodt, Jörg Wilting, Tobias Pukrop, Katja Dettmer, Wolfram Gronwald, Peter J. Oefner, Rainer Spang, Dieter Kube
Published 2020-03-01