Local induction of immunosuppressive CD8+ T cells in the gut-associated lymphoid tissues.

by Diana Fleissner, Wiebke Hansen, Robert Geffers, Jan Buer, Astrid M Westendorf
Published 2010-01-01

Conventional CD11chigh Dendritic Cells Are Important for T Cell Priming during the Initial Phase of Plasmodium yoelii Infection, but Are Dispensable at Later Time Points

by Kristina Ueffing, Hanna Abberger, Astrid M. Westendorf, Kai Matuschewski, Jan Buer, Wiebke Hansen
Published 2017-10-01

Inhibition of TLR4 Signaling Impedes Tumor Growth in Colitis-Associated Colon Cancer

by Eva Pastille, Tabea Faßnacht, Alexandra Adamczyk, Nhi Ngo Thi Phuong, Jan Buer, Astrid M. Westendorf
Published 2021-05-01

Distinct kinetics in the frequency of peripheral CD4+ T cells in patients with ulcerative colitis experiencing a flare during treatment with mesalazine or with a herbal preparation...

by Jost Langhorst, Annika Frede, Markus Knott, Eva Pastille, Jan Buer, Gustav J Dobos, Astrid M Westendorf
Published 2014-01-01

Quantitative Comparison of Abundance Structures of Generalized Communities: From B-Cell Receptor Repertoires to Microbiomes.

by Mohammadkarim Saeedghalati, Farnoush Farahpour, Bettina Budeus, Anja Lange, Astrid M Westendorf, Marc Seifert, Ralf Küppers, Daniel Hoffmann
Published 2017-01-01

Hypoxia Enhances Immunosuppression by Inhibiting CD4+ Effector T Cell Function and Promoting Treg Activity

by Astrid M. Westendorf, Kathrin Skibbe, Alexandra Adamczyk, Jan Buer, Robert Geffers, Wiebke Hansen, Eva Pastille, Verena Jendrossek
Published 2017-03-01

IL10-Deficiency in CD4+ T Cells Exacerbates the IFNγ and IL17 Response During Bacteria Induced Colitis

by Virginia Seiffart, Julia Zoeller, Robert Klopfleisch, Munisch Wadwa, Wiebke Hansen, Jan Buer, Christian Riedel, Astrid M. Westendorf
Published 2015-07-01

IL-33 Drives Expansion of Type 2 Innate Lymphoid Cells and Regulatory T Cells and Protects Mice From Severe, Acute Colitis

by Nhi Ngo Thi Phuong, Vittoria Palmieri, Alexandra Adamczyk, Robert Klopfleisch, Jost Langhorst, Wiebke Hansen, Astrid M. Westendorf, Eva Pastille
Published 2021-07-01

T Cell-Specific Overexpression of Acid Sphingomyelinase Results in Elevated T Cell Activation and Reduced Parasitemia During Plasmodium yoelii Infection

by Matthias Hose, Anne Günther, Hanna Abberger, Salina Begum, Marek Korencak, Katrin A. Becker, Jan Buer, Astrid M. Westendorf, Wiebke Hansen
Published 2019-05-01

Effective Activation of Human Antigen-Presenting Cells and Cytotoxic CD8⁺ T Cells by a Calcium Phosphate-Based Nanoparticle Vaccine Delivery System

by Florian Scheffel, Torben Knuschke, Lucas Otto, Sebastian Kollenda, Viktoriya Sokolova, Christine Cosmovici, Jan Buer, Jörg Timm, Matthias Epple, Astrid M. Westendorf
Published 2020-03-01

Hydrocortisone fails to abolish NF-κB1 protein nuclear translocation in deletion allele carriers of the NFKB1 promoter polymorphism (-94ins/delATTG) and is associated with increase...

by Simon T Schäfer, Sophia Gessner, André Scherag, Katharina Rump, Ulrich H Frey, Winfried Siffert, Astrid M Westendorf, Jörg Steinmann, Jürgen Peters, Michael Adamzik
Published 2014-01-01

Induction of Type I Interferons by Therapeutic Nanoparticle-Based Vaccination Is Indispensable to Reinforce Cytotoxic CD8+ T Cell Responses During Chronic Retroviral Infection

by Torben Knuschke, Olga Rotan, Wibke Bayer, Sebastian Kollenda, Julia Dickow, Kathrin Sutter, Wiebke Hansen, Ulf Dittmer, Karl S. Lang, Matthias Epple, Jan Buer, Astrid M. Westendorf
Published 2018-04-01

CEACAM1 regulates CD8+ T cell immunity and protects from severe pathology during Citrobacter rodentium induced colitis

by Julia Zöller, Jana-Fabienne Ebel, Vishal Khairnar, Verena Schmitt, Robert Klopfleisch, Jana Meiners, Virginia Seiffart, Wiebke Hansen, Jan Buer, Bernhard B. Singer, Karl S. Lang, Astrid M. Westendorf
Published 2020-11-01

Intestinal helminth infection drives carcinogenesis in colitis-associated colon cancer.

by Eva Pastille, Annika Frede, Henry J McSorley, Jessica Gräb, Alexandra Adamczyk, Sebastian Kollenda, Wiebke Hansen, Matthias Epple, Jan Buer, Rick M Maizels, Robert Klopfleisch, Astrid M Westendorf
Published 2017-09-01

Probiotic Escherichia coli Nissle 1917 inhibits leaky gut by enhancing mucosal integrity.

by Sya N Ukena, Anurag Singh, Ulrike Dringenberg, Regina Engelhardt, Ursula Seidler, Wiebke Hansen, André Bleich, Dunja Bruder, Anke Franzke, Gerhard Rogler, Sebastian Suerbaum, Jan Buer, Florian Gunzer, Astrid M Westendorf
Published 2007-12-01

Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota.

by Bärbel Stecher, Riccardo Robbiani, Alan W Walker, Astrid M Westendorf, Manja Barthel, Marcus Kremer, Samuel Chaffron, Andrew J Macpherson, Jan Buer, Julian Parkhill, Gordon Dougan, Christian von Mering, Wolf-Dietrich Hardt
Published 2007-10-01

Sphingosine 1-Phosphate- and C-C Chemokine Receptor 2-Dependent Activation of CD4+ Plasmacytoid Dendritic Cells in the Bone Marrow Contributes to Signs of Sepsis-Induced Immunosupp...

by Anna Smirnov, Stephanie Pohlmann, Melanie Nehring, Shafaqat Ali, Shafaqat Ali, Ritu Mann-Nüttel, Stefanie Scheu, Anne-Charlotte Antoni, Wiebke Hansen, Manuela Büettner, Miriam J. Gardiasch, Astrid M. Westendorf, Florian Wirsdörfer, Eva Pastille, Marcel Dudda, Stefanie B. Flohé
Published 2017-11-01

Virus-Induced Type I Interferon Deteriorates Control of Systemic Pseudomonas Aeruginosa Infection

by Katja Merches, Vishal Khairnar, Torben Knuschke, Namir Shaabani, Nadine Honke, Vikas Duhan, Mike Recher, Alexander A. Navarini, Cornelia Hardt, Dieter Häussinger, Burkhard Tümmler, Erich Gulbins, Anthony H. Futerman, Daniel Hoffmann, Florian Lang, Philipp A. Lang, Astrid M. Westendorf, Karl S. Lang
Published 2015-07-01

Intestinal Acid Sphingomyelinase Protects From Severe Pathogen-Driven Colitis

by Jana Meiners, Vittoria Palmieri, Robert Klopfleisch, Jana-Fabienne Ebel, Lukasz Japtok, Fabian Schumacher, Fabian Schumacher, Ayan Mohamud Yusuf, Katrin A. Becker, Julia Zöller, Matthias Hose, Burkhard Kleuser, Dirk M. Hermann, Richard N. Kolesnick, Jan Buer, Wiebke Hansen, Astrid M. Westendorf
Published 2019-06-01

Modulating gut microbiota in a mouse model of Graves’ orbitopathy and its impact on induced disease

by Sajad Moshkelgosha, Hedda Luise Verhasselt, Giulia Masetti, Danila Covelli, Filippo Biscarini, Mareike Horstmann, Anke Daser, Astrid M. Westendorf, Christoph Jesenek, Svenja Philipp, Salvador Diaz-Cano, J. Paul Banga, Daryn Michael, Sue Plummer, Julian R. Marchesi, Anja Eckstein, Marian Ludgate, Utta Berchner-Pfannschmidt, and the INDIGO consortium
Published 2021-02-01