Genetics of leprosy reactions: an overview

by Vinicius Fava, Marianna Orlova, Aurélie Cobat, Alexandre Alcaïs, Marcelo Mira, Erwin Schurr
Published 2012-12-01

Controlling for human population stratification in rare variant association studies

by Matthieu Bouaziz, Jimmy Mullaert, Benedetta Bigio, Yoann Seeleuthner, Jean-Laurent Casanova, Alexandre Alcais, Laurent Abel, Aurélie Cobat
Published 2021-09-01

The complex pattern of genetic associations of leprosy with HLA class I and class II alleles can be reduced to four amino acid positions.

by Monica Dallmann-Sauer, Vinicius M Fava, Chaïma Gzara, Marianna Orlova, Nguyen Van Thuc, Vu Hong Thai, Alexandre Alcaïs, Laurent Abel, Aurélie Cobat, Erwin Schurr
Published 2020-08-01

Deciphering the genetic control of gene expression following Mycobacterium leprae antigen stimulation.

by Jérémy Manry, Yohann Nédélec, Vinicius M Fava, Aurélie Cobat, Marianna Orlova, Nguyen Van Thuc, Vu Hong Thai, Guillaume Laval, Luis B Barreiro, Erwin Schurr
Published 2017-08-01

Pauci- and Multibacillary Leprosy: Two Distinct, Genetically Neglected Diseases.

by Jean Gaschignard, Audrey Virginia Grant, Nguyen Van Thuc, Marianna Orlova, Aurélie Cobat, Nguyen Thu Huong, Nguyen Ngoc Ba, Vu Hong Thai, Laurent Abel, Erwin Schurr, Alexandre Alcaïs
Published 2016-05-01

Gene set signature of reversal reaction type I in leprosy patients.

by Marianna Orlova, Aurélie Cobat, Nguyen Thu Huong, Nguyen Ngoc Ba, Nguyen Van Thuc, John Spencer, Yohann Nédélec, Luis Barreiro, Vu Hong Thai, Laurent Abel, Alexandre Alcaïs, Erwin Schurr
Published 2013-01-01

Family-based genome-wide association study of leprosy in Vietnam.

by Chaima Gzara, Monica Dallmann-Sauer, Marianna Orlova, Nguyen Van Thuc, Vu Hong Thai, Vinicius M Fava, Marie-Thérèse Bihoreau, Anne Boland, Laurent Abel, Alexandre Alcaïs, Erwin Schurr, Aurélie Cobat
Published 2020-05-01

A Missense LRRK2 Variant Is a Risk Factor for Excessive Inflammatory Responses in Leprosy.

by Vinicius M Fava, Jérémy Manry, Aurélie Cobat, Marianna Orlova, Nguyen Van Thuc, Nguyen Ngoc Ba, Vu Hong Thai, Laurent Abel, Alexandre Alcaïs, Erwin Schurr, Canadian Lrrk2 in Inflammation Team (CLINT)
Published 2016-02-01

PARK2 mediates interleukin 6 and monocyte chemoattractant protein 1 production by human macrophages.

by Louis de Léséleuc, Marianna Orlova, Aurelie Cobat, Manon Girard, Nguyen Thu Huong, Nguyen Ngoc Ba, Nguyen Van Thuc, Richard Truman, John S Spencer, Linda Adams, Vu Hong Thai, Alexandre Alcais, Erwin Schurr
Published 2013-01-01

Combined linkage and association studies show that HLA class II variants control levels of antibodies against Epstein-Barr virus antigens.

by Vincent Pedergnana, Laurène Syx, Aurélie Cobat, Julien Guergnon, Pauline Brice, Christophe Fermé, Patrice Carde, Olivier Hermine, Catherine Le-Pendeven, Corinne Amiel, Yassine Taoufik, Alexandre Alcaïs, Ioannis Theodorou, Caroline Besson, Laurent Abel
Published 2014-01-01

A genome wide association study identifies a lncRna as risk factor for pathological inflammatory responses in leprosy.

by Vinicius M Fava, Jeremy Manry, Aurélie Cobat, Marianna Orlova, Nguyen Van Thuc, Milton O Moraes, Carolinne Sales-Marques, Mariane M A Stefani, Ana Carla P Latini, Andrea F Belone, Vu Hong Thai, Laurent Abel, Alexandre Alcaïs, Erwin Schurr
Published 2017-02-01

Impact of IL28B, APOH and ITPA Polymorphisms on Efficacy and Safety of TVR- or BOC-Based Triple Therapy in Treatment-Experienced HCV-1 Patients with Compensated Cirrhosis from the...

by Frédégonde About, Tiphaine Oudot-Mellakh, Jonathan Niay, Pascaline Rabiéga, Vincent Pedergnana, Darragh Duffy, Philippe Sultanik, Carole Cagnot, Fabrice Carrat, Patrick Marcellin, Fabien Zoulim, Dominique Larrey, Christophe Hézode, Hélène Fontaine, Jean-Pierre Bronowicki, Stanislas Pol, Matthew L Albert, Ioannis Theodorou, Aurélie Cobat, Laurent Abel, ANRS CO20-CUPIC study group
Published 2015-01-01

Genome-wide association study of resistance to Mycobacterium tuberculosis infection identifies a locus at 10q26.2 in three distinct populations.

by Jocelyn Quistrebert, Marianna Orlova, Gaspard Kerner, Le Thi Ton, Nguyễn Trong Luong, Nguyễn Thanh Danh, Quentin B Vincent, Fabienne Jabot-Hanin, Yoann Seeleuthner, Jacinta Bustamante, Stéphanie Boisson-Dupuis, Nguyen Thu Huong, Nguyen Ngoc Ba, Jean-Laurent Casanova, Christophe Delacourt, Eileen G Hoal, Alexandre Alcaïs, Vu Hong Thai, Lai The Thành, Laurent Abel, Erwin Schurr, Aurélie Cobat
Published 2021-03-01

Distinct antibody repertoires against endemic human coronaviruses in children and adults

by Taushif Khan, Mahbuba Rahman, Fatima Al Ali, Susie S. Y. Huang, Manar Ata, Qian Zhang, Paul Bastard, Zhiyong Liu, Emmanuelle Jouanguy, Vivien Béziat, Aurélie Cobat, Gheyath K. Nasrallah, Hadi M. Yassine, Maria K. Smatti, Amira Saeed, Isabelle Vandernoot, Jean-Christophe Goffard, Guillaume Smits, Isabelle Migeotte, Filomeen Haerynck, Isabelle Meyts, Laurent Abel, Jean-Laurent Casanova, Mohammad R. Hasan, Nico Marr
Published 2021-02-01

Identification of an Endoglin Variant Associated With HCV-Related Liver Fibrosis Progression by Next-Generation Sequencing

by Frédégonde About, Frédégonde About, Stéphanie Bibert, Emmanuelle Jouanguy, Emmanuelle Jouanguy, Bertrand Nalpas, Lazaro Lorenzo, Lazaro Lorenzo, Vimel Rattina, Vimel Rattina, Mohammed Zarhrate, Sylvain Hanein, Sylvain Hanein, Mona Munteanu, Beat Müllhaupt, David Semela, Nasser Semmo, Jean-Laurent Casanova, Jean-Laurent Casanova, Jean-Laurent Casanova, Jean-Laurent Casanova, Jean-Laurent Casanova, Ioannis Theodorou, Philippe Sultanik, Thierry Poynard, Thierry Poynard, Stanislas Pol, Pierre-Yves Bochud, Aurélie Cobat, Aurélie Cobat, Laurent Abel, Laurent Abel, Laurent Abel, The Swiss Hepatitis C Cohort Study Group, The French ANRS HC EP 26 Genoscan Study Group, Francesco Negro, Antoine Hadengue, Laurent Kaiser, Laura Rubbia-Brandt, Darius Moradpour, Cristina Cellerai, Martin Rickenbach, Andreas Cerny, Gladys Martinetti, Jean-François Dufour, Meri Gorgievski, Virginie Masserey Spicher, Markus Heim, Hans Hirsch, Beat Helbling, Stephan Regenass, Raffaele Malinverni, Guenter Dollenmaier, Gieri Cathomas
Published 2019-11-01

Prevalence and risk factors for latent tuberculosis infection among healthcare workers in Morocco.

by Ayoub Sabri, Jocelyn Quistrebert, Hicham Naji Amrani, Ahmed Abid, Adil Zegmout, Ismail Abderrhamani Ghorfi, Hicham Souhi, Abdelhalim Boucaid, Anas Benali, Rachid Abilkassem, Mohamed Kmari, Amal Hassani, Belyamani Lahcen, Samir Siah, Erwin Schurr, Stéphanie Boisson-Dupuis, Jean-Laurent Casanova, Amine Lahlou, Abdelkader Laatiris, Lhoussain Louzi, Aziz Ouarssani, Ahmed Bourazza, Aziz Aouragh, Bensghir Mustapha, Nezha Messaoudi, Aomar Agader, Aurélie Cobat, Laurent Abel, Jamila El Baghdadi
Published 2019-01-01

Inhibition of HECT E3 ligases as potential therapy for COVID-19

by Giuseppe Novelli, Jing Liu, Michela Biancolella, Tonino Alonzi, Antonio Novelli, J. J. Patten, Dario Cocciadiferro, Emanuele Agolini, Vito Luigi Colona, Barbara Rizzacasa, Rosalinda Giannini, Benedetta Bigio, Delia Goletti, Maria Rosaria Capobianchi, Sandro Grelli, Justin Mann, Trevor D. McKee, Ke Cheng, Fatima Amanat, Florian Krammer, Andrea Guarracino, Gerardo Pepe, Carlo Tomino, Yacine Tandjaoui-Lambiotte, Yurdagul Uzunhan, Sarah Tubiana, Jade Ghosn, COVID Human Genetic Effort, French COVID Cohort Study Group, CoV-Contact Cohort, Luigi D. Notarangelo, Helen C. Su, Laurent Abel, Aurélie Cobat, Gai Elhanan, Joseph J. Grzymski, Andrea Latini, Sachdev S. Sidhu, Suresh Jain, Robert A. Davey, Jean-Laurent Casanova, Wenyi Wei, Pier Paolo Pandolfi
Published 2021-03-01