Oldies but Goldies mtDNA Population Variants and Neurodegenerative Diseases

by Patrick F. Chinnery, Patrick F. Chinnery, Aurora Gomez-Duran, Aurora Gomez-Duran
Published 2018-10-01

Correction: Background sequence characteristics influence the occurrence and severity of disease-causing mtDNA mutations.

by Wei Wei, Aurora Gomez-Duran, Gavin Hudson, Patrick F Chinnery
Published 2018-05-01

Background sequence characteristics influence the occurrence and severity of disease-causing mtDNA mutations.

by Wei Wei, Aurora Gomez-Duran, Gavin Hudson, Patrick F Chinnery
Published 2017-12-01

Recent mitochondrial DNA mutations increase the risk of developing common late-onset human diseases.

by Gavin Hudson, Aurora Gomez-Duran, Ian J Wilson, Patrick F Chinnery
Published 2014-05-01

Exposure of Monocytic Cells to Lipopolysaccharide Induces Coordinated Endotoxin Tolerance, Mitochondrial Biogenesis, Mitophagy, and Antioxidant Defenses

by John D. Widdrington, John D. Widdrington, Aurora Gomez-Duran, Aurora Gomez-Duran, Aurora Gomez-Duran, Angela Pyle, Marie-Helene Ruchaud-Sparagano, Jonathan Scott, Simon V. Baudouin, Anthony J. Rostron, Penny E. Lovat, Patrick F. Chinnery, Patrick F. Chinnery, Patrick F. Chinnery, A. John Simpson
Published 2018-09-01

Oxygen tension modulates the mitochondrial genetic bottleneck and influences the segregation of a heteroplasmic mtDNA variant in vitro

by Mikael G. Pezet, Aurora Gomez-Duran, Florian Klimm, Juvid Aryaman, Stephen Burr, Wei Wei, Mitinori Saitou, Julien Prudent, Patrick F. Chinnery
Published 2021-05-01

Metabolic effects of bezafibrate in mitochondrial disease

by Hannah Steele, Aurora Gomez‐Duran, Angela Pyle, Sila Hopton, Jane Newman, Renae J Stefanetti, Sarah J Charman, Jehill D Parikh, Langping He, Carlo Viscomi, Djordje G Jakovljevic, Kieren G Hollingsworth, Alan J Robinson, Robert W Taylor, Leonardo Bottolo, Rita Horvath, Patrick F Chinnery
Published 2020-03-01

Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila

by Simonetta Andreazza, Colby L. Samstag, Alvaro Sanchez-Martinez, Erika Fernandez-Vizarra, Aurora Gomez-Duran, Juliette J. Lee, Roberta Tufi, Michael J. Hipp, Elizabeth K. Schmidt, Thomas J. Nicholls, Payam A. Gammage, Patrick F. Chinnery, Michal Minczuk, Leo J. Pallanck, Scott R. Kennedy, Alexander J. Whitworth
Published 2019-07-01

Mutations in mitochondrial DNA causing tubulointerstitial kidney disease.

by Thomas M Connor, Simon Hoer, Andrew Mallett, Daniel P Gale, Aurora Gomez-Duran, Viktor Posse, Robin Antrobus, Pablo Moreno, Marco Sciacovelli, Christian Frezza, Jennifer Duff, Neil S Sheerin, John A Sayer, Margaret Ashcroft, Michael S Wiesener, Gavin Hudson, Claes M Gustafsson, Patrick F Chinnery, Patrick H Maxwell
Published 2017-03-01