Uncovering cancer vulnerabilities by machine learning prediction of synthetic lethality

by Salvatore Benfatto, Özdemirhan Serçin, Francesca R. Dejure, Amir Abdollahi, Frank T. Zenke, Balca R. Mardin
Published 2021-08-01

Systematic Identification of Determinants for Single-Strand Annealing-Mediated Deletion Formation in Saccharomyces cerevisiae

by Maia Segura-Wang, Megumi Onishi-Seebacher, Adrian M. Stütz, Balca R. Mardin, Jan O. Korbel
Published 2017-10-01

Negative Selection and Chromosome Instability Induced by Mad2 Overexpression Delay Breast Cancer but Facilitate Oncogene-Independent Outgrowth

by Konstantina Rowald, Martina Mantovan, Joana Passos, Christopher Buccitelli, Balca R. Mardin, Jan O. Korbel, Martin Jechlinger, Rocio Sotillo
Published 2016-06-01

A scalable CRISPR/Cas9-based fluorescent reporter assay to study DNA double-strand break repair choice

by Paris Roidos, Stephanie Sungalee, Salvatore Benfatto, Özdemirhan Serçin, Adrian M. Stütz, Amir Abdollahi, Jan Mauer, Frank T. Zenke, Jan O. Korbel, Balca R. Mardin
Published 2020-08-01

Systems approaches identify the consequences of monosomy in somatic human cells

by Narendra Kumar Chunduri, Paul Menges, Xiaoxiao Zhang, Angela Wieland, Vincent Leon Gotsmann, Balca R. Mardin, Christopher Buccitelli, Jan O. Korbel, Felix Willmund, Maik Kschischo, Markus Raeschle, Zuzana Storchova
Published 2021-09-01

Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells

by Alexandros P. Drainas, Ruxandra A. Lambuta, Irina Ivanova, Özdemirhan Serçin, Ioannis Sarropoulos, Mike L. Smith, Theocharis Efthymiopoulos, Benjamin Raeder, Adrian M. Stütz, Sebastian M. Waszak, Balca R. Mardin, Jan O. Korbel
Published 2020-04-01

A solid‐phase transfection platform for arrayed CRISPR screens

by Özdemirhan Serçin, Sabine Reither, Paris Roidos, Nadja Ballin, Spyridon Palikyras, Anna Baginska, Katrin Rein, Maria Llamazares, Aliaksandr Halavatyi, Hauke Winter, Thomas Muley, Renata Z Jurkowska, Amir Abdollahi, Frank T Zenke, Beate Neumann, Balca R Mardin
Published 2020-06-01

A solid‐phase transfection platform for arrayed CRISPR screens

by Özdemirhan Serçin, Sabine Reither, Paris Roidos, Nadja Ballin, Spyridon Palikyras, Anna Baginska, Katrin Rein, Maria Llamazares, Aliaksandr Halavatyi, Hauke Winter, Thomas Muley, Renata Z Jurkowska, Amir Abdollahi, Frank T Zenke, Beate Neumann, Balca R Mardin
Published 2019-12-01