Effects of the COVID-19 pandemic on life scientists

by Jan O. Korbel, Oliver Stegle
Published 2020-05-01

Genomic data sharing in Europe is stumbling—Could a code of conduct prevent its fall?

by Fruzsina Molnár‐Gábor, Jan O Korbel
Published 2020-03-01

Computing patient data in the cloud: practical and legal considerations for genetics and genomics research in Europe and internationally

by Fruzsina Molnár-Gábor, Rupert Lueck, Sergei Yakneen, Jan O. Korbel
Published 2017-06-01

InTAD: chromosome conformation guided analysis of enhancer target genes

by Konstantin Okonechnikov, Serap Erkek, Jan O. Korbel, Stefan M. Pfister, Lukas Chavez
Published 2019-01-01

Systematic Identification of Determinants for Single-Strand Annealing-Mediated Deletion Formation in Saccharomyces cerevisiae

by Maia Segura-Wang, Megumi Onishi-Seebacher, Adrian M. Stütz, Balca R. Mardin, Jan O. Korbel
Published 2017-10-01

Acquisition of chromosome instability is a mechanism to evade oncogene addiction

by Lorena Salgueiro, Christopher Buccitelli, Konstantina Rowald, Kalman Somogyi, Sridhar Kandala, Jan O Korbel, Rocio Sotillo
Published 2020-03-01

Dense and accurate whole-chromosome haplotyping of individual genomes

by David Porubsky, Shilpa Garg, Ashley D. Sanders, Jan O. Korbel, Victor Guryev, Peter M. Lansdorp, Tobias Marschall
Published 2017-11-01

Negative Selection and Chromosome Instability Induced by Mad2 Overexpression Delay Breast Cancer but Facilitate Oncogene-Independent Outgrowth

by Konstantina Rowald, Martina Mantovan, Joana Passos, Christopher Buccitelli, Balca R. Mardin, Jan O. Korbel, Martin Jechlinger, Rocio Sotillo
Published 2016-06-01

Systematic association of genes to phenotypes by genome and literature mining.

by Jan O Korbel, Tobias Doerks, Lars J Jensen, Carolina Perez-Iratxeta, Szymon Kaczanowski, Sean D Hooper, Miguel A Andrade, Peer Bork
Published 2005-05-01

A scalable CRISPR/Cas9-based fluorescent reporter assay to study DNA double-strand break repair choice

by Paris Roidos, Stephanie Sungalee, Salvatore Benfatto, Özdemirhan Serçin, Adrian M. Stütz, Amir Abdollahi, Jan Mauer, Frank T. Zenke, Jan O. Korbel, Balca R. Mardin
Published 2020-08-01

Systematic inference of copy-number genotypes from personal genome sequencing data reveals extensive olfactory receptor gene content diversity.

by Sebastian M Waszak, Yehudit Hasin, Thomas Zichner, Tsviya Olender, Ifat Keydar, Miriam Khen, Adrian M Stütz, Andreas Schlattl, Doron Lancet, Jan O Korbel
Published 2010-11-01

High-resolution copy-number variation map reflects human olfactory receptor diversity and evolution.

by Yehudit Hasin, Tsviya Olender, Miriam Khen, Claudia Gonzaga-Jauregui, Philip M Kim, Alexander Eckehart Urban, Michael Snyder, Mark B Gerstein, Doron Lancet, Jan O Korbel
Published 2008-11-01

The baker's yeast diploid genome is remarkably stable in vegetative growth and meiosis.

by K T Nishant, Wu Wei, Eugenio Mancera, Juan Lucas Argueso, Andreas Schlattl, Nicolas Delhomme, Xin Ma, Carlos D Bustamante, Jan O Korbel, Zhenglong Gu, Lars M Steinmetz, Eric Alani
Published 2010-09-01

Systems approaches identify the consequences of monosomy in somatic human cells

by Narendra Kumar Chunduri, Paul Menges, Xiaoxiao Zhang, Angela Wieland, Vincent Leon Gotsmann, Balca R. Mardin, Christopher Buccitelli, Jan O. Korbel, Felix Willmund, Maik Kschischo, Markus Raeschle, Zuzana Storchova
Published 2021-09-01

Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells

by Alexandros P. Drainas, Ruxandra A. Lambuta, Irina Ivanova, Özdemirhan Serçin, Ioannis Sarropoulos, Mike L. Smith, Theocharis Efthymiopoulos, Benjamin Raeder, Adrian M. Stütz, Sebastian M. Waszak, Balca R. Mardin, Jan O. Korbel
Published 2020-04-01

PDX models recapitulate the genetic and epigenetic landscape of pediatric T‐cell leukemia

by Paulina Richter‐Pechańska, Joachim B Kunz, Beat Bornhauser, Caroline vonKnebel Doeberitz, Tobias Rausch, Büşra Erarslan‐Uysal, Yassen Assenov, Viktoras Frismantas, Blerim Marovca, Sebastian M Waszak, Martin Zimmermann, Julia Seemann, Margit Happich, Martin Stanulla, Martin Schrappe, Gunnar Cario, Gabriele Escherich, Kseniya Bakharevich, Renate Kirschner‐Schwabe, Cornelia Eckert, Martina U Muckenthaler, Jan O Korbel, Jean‐Pierre Bourquin, Andreas E Kulozik
Published 2018-12-01

A comprehensive map of mobile element insertion polymorphisms in humans.

by Chip Stewart, Deniz Kural, Michael P Strömberg, Jerilyn A Walker, Miriam K Konkel, Adrian M Stütz, Alexander E Urban, Fabian Grubert, Hugo Y K Lam, Wan-Ping Lee, Michele Busby, Amit R Indap, Erik Garrison, Chad Huff, Jinchuan Xing, Michael P Snyder, Lynn B Jorde, Mark A Batzer, Jan O Korbel, Gabor T Marth, 1000 Genomes Project
Published 2011-08-01

Chromatin accessibility landscape of pediatric T‐lymphoblastic leukemia and human T‐cell precursors

by Büşra Erarslan‐Uysal, Joachim B Kunz, Tobias Rausch, Paulina Richter‐Pechańska, Ianthe AEM vanBelzen, Viktoras Frismantas, Beat Bornhauser, Diana Ordoñez‐Rueada, Malte Paulsen, Vladimir Benes, Martin Stanulla, Martin Schrappe, Gunnar Cario, Gabriele Escherich, Kseniya Bakharevich, Renate Kirschner‐Schwabe, Cornelia Eckert, Tsvetomir Loukanov, Matthias Gorenflo, Sebastian M Waszak, Jean‐Pierre Bourquin, Martina U Muckenthaler, Jan O Korbel, Andreas E Kulozik
Published 2020-09-01

Genomic structural variations lead to dysregulation of important coding and non‐coding RNA species in dilated cardiomyopathy

by Jan Haas, Stefan Mester, Alan Lai, Karen S Frese, Farbod Sedaghat‐Hamedani, Elham Kayvanpour, Tobias Rausch, Rouven Nietsch, Jes‐Niels Boeckel, Avisha Carstensen, Mirko Völkers, Carsten Dietrich, Dietmar Pils, Ali Amr, Daniel B Holzer, Diana Martins Bordalo, Daniel Oehler, Tanja Weis, Derliz Mereles, Sebastian Buss, Eva Riechert, Emil Wirsz, Maximilian Wuerstle, Jan O Korbel, Andreas Keller, Hugo A Katus, Andreas E Posch, Benjamin Meder
Published 2018-01-01

Versatile workflow for cell type–resolved transcriptional and epigenetic profiles from cryopreserved human lung

by Maria Llamazares-Prada, Elisa Espinet, Vedrana Mijošek, Uwe Schwartz, Pavlo Lutsik, Raluca Tamas, Mandy Richter, Annika Behrendt, Stephanie T. Pohl, Naja P. Benz, Thomas Muley, Arne Warth, Claus Peter Heußel, Hauke Winter, Jonathan J. M. Landry, Felix J.F. Herth, Tinne C.J. Mertens, Harry Karmouty-Quintana, Ina Koch, Vladimir Benes, Jan O. Korbel, Sebastian M. Waszak, Andreas Trumpp, David M. Wyatt, Heiko F. Stahl, Christoph Plass, Renata Z. Jurkowska
Published 2021-03-01