Epigenetic signatures in cancer: proper controls, current challenges and the potential for clinical translation

by Daniela Mancarella, Christoph Plass
Published 2021-02-01

Mining methylation for early detection of common cancers.

by Romulo M Brena, Christoph Plass, Joseph F Costello
Published 2006-12-01

RASSF1A Promoter Methylation and Kras2 Mutations in Non Small Cell Lung Cancer

by Jie Li, Zhongqiu Zhang, Zunyan Dai, Anthony P. Popkie, Christoph Plass, Carl Morrison, Yian Wang, Ming You
Published 2003-07-01

Neuronal ensemble-specific DNA methylation strengthens engram stability

by Kubra Gulmez Karaca, Janina Kupke, David V. C. Brito, Benjamin Zeuch, Christian Thome, Dieter Weichenhan, Pavlo Lutsik, Christoph Plass, Ana M. M. Oliveira
Published 2020-01-01

Association of inherited variation in Toll-like receptor genes with malignant melanoma susceptibility and survival.

by Andreas Gast, Justo Lorenzo Bermejo, Rainer Claus, Andreas Brandt, Marianne Weires, Alexander Weber, Christoph Plass, Antje Sucker, Kari Hemminki, Dirk Schadendorf, Rajiv Kumar
Published 2011-01-01

DNA methylation signatures of monozygotic twins clinically discordant for multiple sclerosis

by Nicole Y. Souren, Lisa A. Gerdes, Pavlo Lutsik, Gilles Gasparoni, Eduardo Beltrán, Abdulrahman Salhab, Tania Kümpfel, Dieter Weichenhan, Christoph Plass, Reinhard Hohlfeld, Jörn Walter
Published 2019-05-01

Aberrant DNA methylation of OLIG1, a novel prognostic factor in non-small cell lung cancer.

by Romulo M Brena, Carl Morrison, Sandya Liyanarachchi, David Jarjoura, Ramana V Davuluri, Gregory A Otterson, David Reisman, Selina Glaros, Laura J Rush, Christoph Plass
Published 2007-03-01

HOXB13, a target of DNMT3B, is methylated at an upstream CpG island, and functions as a tumor suppressor in primary colorectal tumors.

by Kalpana Ghoshal, Tasneem Motiwala, Rainer Claus, Pearlly Yan, Huban Kutay, Jharna Datta, Sarmila Majumder, Shoumei Bai, Arnab Majumder, Tim Huang, Christoph Plass, Samson T Jacob
Published 2010-04-01

Melanoma-Derived iPCCs Show Differential Tumorigenicity and Therapy Response

by Mathias Bernhardt, Daniel Novak, Yassen Assenov, Elias Orouji, Nathalie Knappe, Kasia Weina, Maike Reith, Lionel Larribere, Christoffer Gebhardt, Christoph Plass, Viktor Umansky, Jochen Utikal
Published 2017-05-01

The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium

by Katharina Schlereth, Dieter Weichenhan, Tobias Bauer, Tina Heumann, Evangelia Giannakouri, Daniel Lipka, Samira Jaeger, Matthias Schlesner, Patrick Aloy, Roland Eils, Christoph Plass, Hellmut G Augustin
Published 2018-05-01

Loss of DNMT1o disrupts imprinted X chromosome inactivation and accentuates placental defects in females.

by Serge McGraw, Christopher C Oakes, Josée Martel, M Cecilia Cirio, Pauline de Zeeuw, Winifred Mak, Christoph Plass, Marisa S Bartolomei, J Richard Chaillet, Jacquetta M Trasler
Published 2013-11-01

Germline allele-specific expression of DAPK1 in chronic lymphocytic leukemia.

by Quan-Xiang Wei, Rainer Claus, Thomas Hielscher, Daniel Mertens, Aparna Raval, Christopher C Oakes, Stephan M Tanner, Albert de la Chapelle, John C Byrd, Stephan Stilgenbauer, Christoph Plass
Published 2013-01-01

Altered DNA Methylation Profiles in <i>SF3B1</i> Mutated CLL Patients

by Alicja Pacholewska, Christina Grimm, Carmen D. Herling, Matthias Lienhard, Anja Königs, Bernd Timmermann, Janine Altmüller, Oliver Mücke, Hans Christian Reinhardt, Christoph Plass, Ralf Herwig, Michael Hallek, Michal R. Schweiger
Published 2021-08-01

Bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction

by Christoph Niemöller, Julius Wehrle, Julian Riba, Rainer Claus, Nathalie Renz, Janika Rhein, Sabine Bleul, Juliane M. Stosch, Justus Duyster, Christoph Plass, Pavlo Lutsik, Daniel B. Lipka, Michael Lübbert, Heiko Becker
Published 2021-02-01

Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia

by Elliot Stieglitz, Tali Mazor, Adam B. Olshen, Huimin Geng, Laura C. Gelston, Jon Akutagawa, Daniel B. Lipka, Christoph Plass, Christian Flotho, Farid F. Chehab, Benjamin S. Braun, Joseph F. Costello, Mignon L. Loh
Published 2017-12-01

Global Methylation Profiling of Lung Cancer Identifies Novel Methylated Genes

by Zunyan Dai, Romola R. Lakshmanan, Wei-Guo Zhu, Dominic J. Smiraglia, Laura J. Rush, Michael C. Frühwald, Romulo M. Brena, Bin Li, Fred A. Wright, Patrick Ross, Gregory A. Otterson, Christoph Plass
Published 2001-01-01

Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability

by Cornelia Jäkel, Frank Bergmann, Reka Toth, Yassen Assenov, Daniel van der Duin, Oliver Strobel, Thomas Hank, Günter Klöppel, Craig Dorrell, Markus Grompe, Joshua Moss, Yuval Dor, Peter Schirmacher, Christoph Plass, Odilia Popanda, Peter Schmezer
Published 2017-11-01

LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells

by Ani Grigoryan, Novella Guidi, Katharina Senger, Thomas Liehr, Karin Soller, Gina Marka, Angelika Vollmer, Yolanda Markaki, Heinrich Leonhardt, Christian Buske, Daniel B. Lipka, Christoph Plass, Yi Zheng, Medhanie A. Mulaw, Hartmut Geiger, Maria Carolina Florian
Published 2018-11-01

CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells.

by Rene Opavsky, Shu-Huei Wang, Prashant Trikha, Aparna Raval, Yuan Huang, Yue-Zhong Wu, Benjamin Rodriguez, Benjamin Keller, Sandya Liyanarachchi, Guo Wei, Ramana V Davuluri, Michael Weinstein, Dean Felsher, Michael Ostrowski, Gustavo Leone, Christoph Plass
Published 2007-09-01

Identification of Cell Type-Specific Differences in Erythropoietin Receptor Signaling in Primary Erythroid and Lung Cancer Cells.

by Ruth Merkle, Bernhard Steiert, Florian Salopiata, Sofia Depner, Andreas Raue, Nao Iwamoto, Max Schelker, Helge Hass, Marvin Wäsch, Martin E Böhm, Oliver Mücke, Daniel B Lipka, Christoph Plass, Wolf D Lehmann, Clemens Kreutz, Jens Timmer, Marcel Schilling, Ursula Klingmüller
Published 2016-08-01