Markus Grompe
Markus Grompe is a professor of Pediatrics and practicing physician at Oregon Health & Science University. since 1991. Since 2004, he has been director of the [https://www.ohsu.edu/stem-cell-center Oregon Stem Cell Center] at OHSU. Until 2018, he was also director of the Papé Family Pediatric Research Institute, Vice Chair for research in the OHSU department of Pediatrics, and holder of the Ray Hickey Endowed Chair at Doernbecher Children's Hospital.Grompe is a specialist in hepatology and stem cell biology, and is known for the development of the "Fah mouse model", a transgenic mouse with an inactivating mutation (exon 5 deletion) in sequence encoding fumarylacetoacetate hydrolase (''Fah''). This mouse strain has been a useful model of Type I tyrosinemia, a human genetic disease caused by inactivating mutations in the ''Fah'' gene. The mice have been used to model diseases such as malaria and to optimize human gene therapy strategies
Dr. Grompe has made major contributions to the study of Fanconi Anemia. His contributions to the study of this rare hematological deficiency has helped to reveal the contributions of the FANC protein complexes associated with the repair of double-stranded breaks in genomic DNA.. He was involved in the establishment of the Fanconi Anemia Research Materials repository which helps to facilitate Fanconi anemia research through the distribution of antibodies and cell lines free of charge to interested investigators.
In 2007 Grompe founded [https://www.yecuris.com/ Yecuris Corporation], which distributes mice with "humanized" livers to pharmaceutical and biotech companies for pre-clinical research in infectious liver diseases, liver gene therapy, and drug metabolism.
In 2016, he cofounded [https://www.ambys.com/ Ambys Medicines], which develops treatments for advanced liver disease through enhancement or regeneration of hepatocyte activity. Provided by Wikipedia
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1by Tomonori Matsumoto, Leslie Wakefield, Alexander Peters, Myron Peto, Paul Spellman, Markus GrompeGet full text
Published 2021-01-01
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2by Bin Li, Craig Dorrell, Pamela S. Canaday, Carl Pelz, Annelise Haft, Milton Finegold, Markus GrompeGet full text
Published 2017-08-01
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3by Feorillo H. Galivo, Craig Dorrell, Maria T. Grompe, YongPing Zhong, Philip R. Streeter, Markus GrompeGet full text
Published 2015-07-01
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4by Feorillo Galivo, Eric Benedetti, Yuhan Wang, Carl Pelz, Jonathan Schug, Klaus H Kaestner, Markus GrompeGet full text
Published 2017-01-01
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6by Daelyn Y. Richards, Shelley R. Winn, Sandra Dudley, Sean Nygaard, Taylor L. Mighell, Markus Grompe, Cary O. HardingGet full text
Published 2020-06-01
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7by Andrew W Duncan, Raymond D Hickey, Nicole K Paulk, Andrew J Culberson, Susan B Olson, Milton J Finegold, Markus GrompeGet full text
Published 2009-02-01
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10by Craig Dorrell, Branden Tarlow, Yuhan Wang, Pamela S. Canaday, Annelise Haft, Jonathan Schug, Philip R. Streeter, Milton J. Finegold, Lincoln T. Shenje, Klaus H. Kaestner, Markus GrompeGet full text
Published 2014-09-01
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12by Qing-Shuo Zhang, Eric Benedetti, Matthew Deater, Kathryn Schubert, Angela Major, Carl Pelz, Soren Impey, Laura Marquez-Loza, R. Keaney Rathbun, Shigeaki Kato, Grover C. Bagby, Markus GrompeGet full text
Published 2015-01-01
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13by Raymond D. Hickey, Shennen A. Mao, Jaime Glorioso, Joseph B. Lillegard, James E. Fisher, Bruce Amiot, Piero Rinaldo, Cary O. Harding, Ronald Marler, Milton J. Finegold, Markus Grompe, Scott L. NybergGet full text
Published 2014-07-01
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14by Ewa C S Ellis, Willscott Edward Naugler, Paolo Parini, Lisa-Mari Mörk, Carl Jorns, Helen Zemack, Anita Lövgren Sandblom, Ingemar Björkhem, Bo-Göran Ericzon, Elizabeth M Wilson, Stephen C Strom, Markus GrompeGet full text
Published 2013-01-01
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15by Cornelia Jäkel, Frank Bergmann, Reka Toth, Yassen Assenov, Daniel van der Duin, Oliver Strobel, Thomas Hank, Günter Klöppel, Craig Dorrell, Markus Grompe, Joshua Moss, Yuval Dor, Peter Schirmacher, Christoph Plass, Odilia Popanda, Peter SchmezerGet full text
Published 2017-11-01
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16by Kathryn F. Cogger, Ankit Sinha, Farida Sarangi, Emily C. McGaugh, Diane Saunders, Craig Dorrell, Salvador Mejia-Guerrero, Yasaman Aghazadeh, Jillian L. Rourke, Robert A. Screaton, Markus Grompe, Philip R. Streeter, Alvin C. Powers, Marcela Brissova, Thomas Kislinger, M. Cristina NostroGet full text
Published 2017-08-01
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17by Samantha L. Ginn, Anais K. Amaya, Sophia H.Y. Liao, Erhua Zhu, Sharon C. Cunningham, Michael Lee, Claus V. Hallwirth, Grant J. Logan, Szun S. Tay, Anthony J. Cesare, Hilda A. Pickett, Markus Grompe, Kimberley Dilworth, Leszek Lisowski, Ian E. AlexanderGet full text
Published 2020-02-01
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18by Joshua Moss, Judith Magenheim, Daniel Neiman, Hai Zemmour, Netanel Loyfer, Amit Korach, Yaacov Samet, Myriam Maoz, Henrik Druid, Peter Arner, Keng-Yeh Fu, Endre Kiss, Kirsty L. Spalding, Giora Landesberg, Aviad Zick, Albert Grinshpun, A. M. James Shapiro, Markus Grompe, Avigail Dreazan Wittenberg, Benjamin Glaser, Ruth Shemer, Tommy Kaplan, Yuval DorGet full text
Published 2018-11-01
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