Aberrant promoter hypomethylation in CLL: does it matter for disease development?

by Garland Michael Upchurch, Staci Haney, Rene Opavsky
Published 2016-08-01

Dnmt3b catalytic activity is critical for its tumour suppressor function in lymphomagenesis and is associated with c-Met oncogenic signalling

by Katarina Lopusna, Pawel Nowialis, Jana Opavska, Ajay Abraham, Alberto Riva, Rene Opavsky
Published 2021-01-01

Rb-mediated neuronal differentiation through cell-cycle-independent regulation of E2f3a.

by Danian Chen, Rene Opavsky, Marek Pacal, Naoyuki Tanimoto, Pamela Wenzel, Mathias W Seeliger, Gustavo Leone, Rod Bremner
Published 2007-07-01

Dnmt3a Is a Haploinsufficient Tumor Suppressor in CD8+ Peripheral T Cell Lymphoma.

by Staci L Haney, G Michael Upchurch, Jana Opavska, David Klinkebiel, Ryan A Hlady, Sohini Roy, Samikshan Dutta, Kaustubh Datta, Rene Opavsky
Published 2016-09-01

Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions

by Pawel Nowialis, Katarina Lopusna, Jana Opavska, Staci L. Haney, Ajay Abraham, Peike Sheng, Alberto Riva, Amarnath Natarajan, Olga Guryanova, Melanie Simpson, Ryan Hlady, Mingyi Xie, Rene Opavsky
Published 2019-09-01

Promoter Hypomethylation and Expression Is Conserved in Mouse Chronic Lymphocytic Leukemia Induced by Decreased or Inactivated Dnmt3a

by Staci L. Haney, G. Michael Upchurch, Jana Opavska, David Klinkebiel, Ryan A. Hlady, Abhinav Suresh, Samuel J. Pirruccello, Vipul Shukla, Runqing Lu, Stefan Costinean, Angie Rizzino, Adam R. Karpf, Shantaram Joshi, Patrick Swanson, Rene Opavsky
Published 2016-05-01

CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells.

by Rene Opavsky, Shu-Huei Wang, Prashant Trikha, Aparna Raval, Yuan Huang, Yue-Zhong Wu, Benjamin Rodriguez, Benjamin Keller, Sandya Liyanarachchi, Guo Wei, Ramana V Davuluri, Michael Weinstein, Dean Felsher, Michael Ostrowski, Gustavo Leone, Christoph Plass
Published 2007-09-01