BRCA2 abrogation triggers innate immune responses potentiated by treatment with PARP inhibitors

by Timo Reisländer, Emilia Puig Lombardi, Florian J. Groelly, Ana Miar, Manuela Porru, Serena Di Vito, Benjamin Wright, Helen Lockstone, Annamaria Biroccio, Adrian Harris, Arturo Londoño-Vallejo, Madalena Tarsounas
Published 2019-07-01

A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells

by Rebecca A. Dagg, Gijs Zonderland, Emilia Puig Lombardi, Giacomo G. Rossetti, Florian J. Groelly, Sonia Barroso, Eliana M. C. Tacconi, Benjamin Wright, Helen Lockstone, Andrés Aguilera, Thanos D. Halazonetis, Madalena Tarsounas
Published 2021-08-01

Transcriptomic Analysis of Inflammatory Cardiomyopathy Identifies Molecular Signatures of Disease and Informs in silico Prediction of a Network-Based Rationale for Therapy

by Kamayani Singh, Kamayani Singh, Hai Fang, Hai Fang, Graham Davies, Graham Davies, Benjamin Wright, Helen Lockstone, Richard O. Williams, Daniela Ciháková, Julian C. Knight, Julian C. Knight, Shoumo Bhattacharya, Shoumo Bhattacharya
Published 2021-03-01