A Model to Investigate Single-Strand DNA Responses in G1 Human Cells via a Telomere-Targeted, Nuclease-Deficient CRISPR-Cas9 System.

by Remco P Crefcoeur, Omar Zgheib, Thanos D Halazonetis
Published 2017-01-01

Enhanced Rate of Acquisition of Point Mutations in Mouse Intestinal Adenomas Compared to Normal Tissue

by Natalia Lugli, Vasilis S. Dionellis, Paloma Ordóñez-Morán, Irene Kamileri, Sotirios K. Sotiriou, Joerg Huelsken, Thanos D. Halazonetis
Published 2017-06-01

Genomic Instability Profiles at the Single Cell Level in Mouse Colorectal Cancers of Defined Genotypes

by Vasilis S. Dionellis, Maxim Norkin, Angeliki Karamichali, Giacomo G. Rossetti, Joerg Huelsken, Paloma Ordonez-Moran, Thanos D. Halazonetis
Published 2021-03-01

Structural basis of transcriptional gene silencing mediated by Arabidopsis MOM1.

by Taisuke Nishimura, Guillaume Molinard, Tom J Petty, Larissa Broger, Caroline Gabus, Thanos D Halazonetis, Stéphane Thore, Jerzy Paszkowski
Published 2012-02-01

A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells

by Rebecca A. Dagg, Gijs Zonderland, Emilia Puig Lombardi, Giacomo G. Rossetti, Florian J. Groelly, Sonia Barroso, Eliana M. C. Tacconi, Benjamin Wright, Helen Lockstone, Andrés Aguilera, Thanos D. Halazonetis, Madalena Tarsounas
Published 2021-08-01

A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening

by Christoph Gorgulla, Krishna M. Padmanabha Das, Kendra E. Leigh, Marco Cespugli, Patrick D. Fischer, Zi-Fu Wang, Guilhem Tesseyre, Shreya Pandita, Alec Shnapir, Anthony Calderaio, Minko Gechev, Alexander Rose, Noam Lewis, Colin Hutcheson, Erez Yaffe, Roni Luxenburg, Henry D. Herce, Vedat Durmaz, Thanos D. Halazonetis, Konstantin Fackeldey, J.J. Patten, Alexander Chuprina, Igor Dziuba, Alla Plekhova, Yurii Moroz, Dmytro Radchenko, Olga Tarkhanova, Irina Yavnyuk, Christian Gruber, Ryan Yust, Dave Payne, Anders M. Näär, Mark N. Namchuk, Robert A. Davey, Gerhard Wagner, Jamie Kinney, Haribabu Arthanari
Published 2021-02-01