Cellular Chaperones As Therapeutic Targets in ALS to Restore Protein Homeostasis and Improve Cellular Function

by Bernadett Kalmar, Linda Greensmith, Linda Greensmith
Published 2017-09-01

Regional Differences in Heat Shock Protein 25 Expression in Brain and Spinal Cord Astrocytes of Wild-Type and SOD1 ^G93A Mice

by Rebecca San Gil, Benjamin E. Clarke, Heath Ecroyd, Bernadett Kalmar, Linda Greensmith
Published 2021-05-01

Plasma neurofilament heavy chain levels correlate to markers of late stage disease progression and treatment response in SOD1(G93A) mice that model ALS.

by Ching-Hua Lu, Axel Petzold, Bernadett Kalmar, James Dick, Andrea Malaspina, Linda Greensmith
Published 2012-01-01

Molecular chaperone mediated late-stage neuroprotection in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.

by Sergey S Novoselov, Wendy J Mustill, Anna L Gray, James R Dick, Naheed Kanuga, Bernadett Kalmar, Linda Greensmith, Michael E Cheetham
Published 2013-01-01

Hereditary sensory neuropathy type 1-associated deoxysphingolipids cause neurotoxicity, acute calcium handling abnormalities and mitochondrial dysfunction in vitro

by Emma R. Wilson, Umaiyal Kugathasan, Andrey Y. Abramov, Alex J. Clark, David L.H. Bennett, Mary M. Reilly, Linda Greensmith, Bernadett Kalmar
Published 2018-09-01

A comprehensive assessment of the SOD1G93A low-copy transgenic mouse, which models human amyotrophic lateral sclerosis

by Abraham Acevedo-Arozena, Bernadett Kalmar, Shafa Essa, Thomas Ricketts, Peter Joyce, Rosie Kent, Claire Rowe, Andy Parker, Anna Gray, Majid Hafezparast, Julian R. Thorpe, Linda Greensmith, Elizabeth M. C. Fisher
Published 2011-09-01

Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration.

by Sheona Watson-Scales, Bernadett Kalmar, Eva Lana-Elola, Dorota Gibbins, Federica La Russa, Frances Wiseman, Matthew Williamson, Rachele Saccon, Amy Slender, Anna Olerinyova, Radma Mahmood, Emma Nye, Heather Cater, Sara Wells, Y Eugene Yu, David L H Bennett, Linda Greensmith, Elizabeth M C Fisher, Victor L J Tybulewicz
Published 2018-05-01