Poly(ADP-Ribose) Regulates Stress Responses and MicroRNA Activity in the Cytoplasm

by Leung, Anthony, Bhutkar, Arjun (AJ), Chang, Paul, Vyas, Sejal Kamlesh, Rood, Jennifer Evelyn, Leung, Anthony, Sharp, Phillip A.
Published 2014

Genome-wide identification of Ago2 binding sites from mouse embryonic stem cells with and without mature microRNAs

by Leung, Anthony, Young, Amanda G., Bhutkar, Arjun (AJ), Zheng, Grace X., Bosson, Andrew David, Nielsen, Cydney B., Sharp, Phillip A.
Published 2012

Caspase-2-Mediated Cleavage of Mdm2 Creates a p53-Induced Positive Feedback Loop

by Oliver, Trudy, Meylan, Etienne, Chang, Gregory P., Xue, Wen, Burke, James R., Humpton, Timothy J., Hubbard, Diana D., Bhutkar, Arjun (AJ), Jacks, Tyler E.
Published 2015

Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts

by Gurtan, Allan M., Ravi, Arvind, Bosson, Andrew David, JnBaptiste, Courtney Kenneil, Bhutkar, Arjun (AJ), Whittaker, Charles A., Young, Richard A., Sharp, Phillip A., Rahl, Peter B.
Published 2014

Proliferation and Tumorigenesis of a Murine Sarcoma Cell Line in the Absence of DICER1

by Ravi, Arvind, Gurtan, Allan M., Kumar, Madhu Sudhan, Chin, Christine, Lu, Victoria, Sharp, Phillip A., Bhutkar, Arjun (AJ), Lees, Jacqueline, Jacks, Tyler E., Sharp, Phillip A., Kumar, Madhu Sudhan
Published 2014

Global microRNA depletion suppresses tumor angiogenesis

by Chen, Sidi, Xue, Yuan, Le, Cong, Bhutkar, Arjun (AJ), Bell, Eric L., Zhang, Feng, Langer, Robert, Sharp, Phillip A., Wu, Xuebing, Ph. D. Massachusetts Institute of Technology, Wu, Xuebing, Ph. D. Massachusetts Institute of Technology
Published 2014

Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer

by Oliver, Trudy, Mercer, Kim L., Sayles, Leanne C., Burke, James R., Mendus, Diana, Lovejoy, Katherine S., Cheng, Mei-Hsin, Subramanian, Aravind, Mu, David, Powers, Scott, Crowley, Denise G., Bronson, Roderick T., Whittaker, Charles A., Bhutkar, Arjun (AJ), Lippard, Stephen J., Golub, Todd R., Thomale, Juergen, Jacks, Tyler E., Sweet-Cordero, E. Alejandro
Published 2011

Detained introns are a novel, widespread class of post-transcriptionally spliced introns

by Sharp, Phillip A., Boutz, Paul, Bhutkar, Arjun
Published 2015

p53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancer

by McFadden, David Glenn, Vernon, Amanda, Santiago, Philip M., Martinez-McFaline, Raul, Crowley, Denise M., McMahon, Martin, Sadow, Peter M., Bhutkar, Arjun, Jacks, Tyler E
Published 2014

Rapid modelling of cooperating genetic events in cancer through somatic genome editing

by Papagiannakopoulos, Thales, Romero, Rodrigo, Tammela, Tuomas, Bauer, Matthew R., Subbaraj, Lakshmipriya, Bronson, Roderick T., Xue, Wen, Sanchez-Rivera, Francisco Jav, Joshi, Nik, Bhutkar, Arjun, Jacks, Tyler E
Published 2015

Foxa2 and Cdx2 cooperate with Nkx2-1 to inhibit lung adenocarcinoma metastasis

by Li, Carman Man-Chung, Gocheva, Vasilena, Wang, Shi Yun, Date, Saya R., Ng, Sheng Rong, Whittaker, Charles A., Bronson, Roderick T., Snyder, Eric L., Oudin, Madeleine Julie, Gertler, Frank, Bhutkar, Arjun, Jacks, Tyler E
Published 2016