CLICK-enabled analogues reveal pregnenolone interactomes in cancer and immune cells

by Sougata Roy, James Sipthorp, Bidesh Mahata, Jhuma Pramanik, Marco L. Hennrich, Anne-Claude Gavin, Steven V. Ley, Sarah A. Teichmann
Published 2021-05-01

Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth

by Sarah Davidson, Mirjana Efremova, Angela Riedel, Bidesh Mahata, Jhuma Pramanik, Jani Huuhtanen, Gozde Kar, Roser Vento-Tormo, Tzachi Hagai, Xi Chen, Muzlifah A. Haniffa, Jacqueline D. Shields, Sarah A. Teichmann
Published 2020-05-01

Genome-wide analyses reveal the IRE1a-XBP1 pathway promotes T helper cell differentiation by resolving secretory stress and accelerating proliferation

by Jhuma Pramanik, Xi Chen, Gozde Kar, Johan Henriksson, Tomás Gomes, Jong-Eun Park, Kedar Natarajan, Kerstin B. Meyer, Zhichao Miao, Andrew N. J. McKenzie, Bidesh Mahata, Sarah A. Teichmann
Published 2018-10-01

Single-Cell RNA Sequencing Reveals T Helper Cells Synthesizing Steroids De Novo to Contribute to Immune Homeostasis

by Bidesh Mahata, Xiuwei Zhang, Aleksandra A. Kolodziejczyk, Valentina Proserpio, Liora Haim-Vilmovsky, Angela E. Taylor, Daniel Hebenstreit, Felix A. Dingler, Victoria Moignard, Berthold Göttgens, Wiebke Arlt, Andrew N.J. McKenzie, Sarah A. Teichmann
Published 2014-05-01

Tumors induce de novo steroid biosynthesis in T cells to evade immunity

by Bidesh Mahata, Jhuma Pramanik, Louise van der Weyden, Krzysztof Polanski, Gozde Kar, Angela Riedel, Xi Chen, Nuno A. Fonseca, Kousik Kundu, Lia S. Campos, Edward Ryder, Graham Duddy, Izabela Walczak, Klaus Okkenhaug, David J. Adams, Jacqueline D. Shields, Sarah A. Teichmann
Published 2020-07-01