Pharmacological activation of pyruvate kinase M2 reprograms glycolysis leading to TXNIP depletion and AMPK activation in breast cancer cells

by Fadi Almouhanna, Biljana Blagojevic, Suzan Can, Ali Ghanem, Stefan Wölfl
Published 2021-01-01

Methylisoindigo and Its Bromo-Derivatives Are Selective Tyrosine Kinase Inhibitors, Repressing Cellular Stat3 Activity, and Target CD133+ Cancer Stem Cells in PDAC

by Jana Tegethoff, Roland Bischoff, Sawsan Saleh, Biljana Blagojevic, Karl-Heinz Merz, Xinlai Cheng
Published 2017-09-01

A Ruthenium(II) <i>N</i>-Heterocyclic Carbene (NHC) Complex with Naphthalimide Ligand Triggers Apoptosis in Colorectal Cancer Cells via Activating the ROS-p38 MAPK Pathway

by Yasamin Dabiri, Alice Schmid, Jannick Theobald, Biljana Blagojevic, Wojciech Streciwilk, Ingo Ott, Stefan Wölfl, Xinlai Cheng
Published 2018-12-01

Activation of pro-survival metabolic networks by 1,25(OH)2D3 does not hamper the sensitivity of breast cancer cells to chemotherapeutics

by Mohamed A. Abu el Maaty, Yasamin Dabiri, Fadi Almouhanna, Biljana Blagojevic, Jannick Theobald, Michael Büttner, Stefan Wölfl
Published 2018-08-01

Severe metabolic alterations in liver cancer lead to ERK pathway activation and drug resistance

by Zeribe Chike Nwosu, Weronika Piorońska, Nadia Battello, Andreas David Zimmer, Bedair Dewidar, Mei Han, Sharon Pereira, Biljana Blagojevic, Darko Castven, Verodia Charlestin, Pavlo Holenya, Julia Lochead, Carolina De La Torre, Norbert Gretz, Peter Sajjakulnukit, Li Zhang, Matthew H. Ward, Jens U. Marquardt, Marina Pasca di Magliano, Costas A. Lyssiotis, Jonathan Sleeman, Stefan Wölfl, Matthias Philip Ebert, Christoph Meyer, Ute Hofmann, Steven Dooley
Published 2020-04-01