Essential role of mitochondrial Stat3 in p38MAPK mediated apoptosis under oxidative stress

by Xinlai Cheng, Christiane Peuckert, Stefan Wölfl
Published 2017-11-01

Pro-oxidant and lifespan extension effects of caffeine and related methylxanthines in Caenorhabditis elegans

by Hanmei Li, Mariana Roxo, Xinlai Cheng, Shaoxiong Zhang, Haoran Cheng, Michael Wink
Published 2019-03-01

Methylisoindigo and Its Bromo-Derivatives Are Selective Tyrosine Kinase Inhibitors, Repressing Cellular Stat3 Activity, and Target CD133+ Cancer Stem Cells in PDAC

by Jana Tegethoff, Roland Bischoff, Sawsan Saleh, Biljana Blagojevic, Karl-Heinz Merz, Xinlai Cheng
Published 2017-09-01

The essential role of TAp73 in bortezomib-induced apoptosis in p53-deficient colorectal cancer cells

by Yasamin Dabiri, Sara Kalman, Clara-Marie Gürth, Jee Young Kim, Viola Mayer, Xinlai Cheng
Published 2017-07-01

Human microRNA-299-3p decreases invasive behavior of cancer cells by downregulation of Oct4 expression and causes apoptosis.

by Axel R Göhring, Stefanie Reuter, Joachim H Clement, Xinlai Cheng, Jannick Theobald, Stefan Wölfl, Ralf Mrowka
Published 2017-01-01

A Ruthenium(II) <i>N</i>-Heterocyclic Carbene (NHC) Complex with Naphthalimide Ligand Triggers Apoptosis in Colorectal Cancer Cells via Activating the ROS-p38 MAPK Pathway

by Yasamin Dabiri, Alice Schmid, Jannick Theobald, Biljana Blagojevic, Wojciech Streciwilk, Ingo Ott, Stefan Wölfl, Xinlai Cheng
Published 2018-12-01

p53-Dependent Anti-Proliferative and Pro-Apoptotic Effects of a Gold(I) N-Heterocyclic Carbene (NHC) Complex in Colorectal Cancer Cells

by Yasamin Dabiri, Mohamed A. Abu el Maaty, Hoi Yin Chan, Hoi Yin Chan, Jessica Wölker, Ingo Ott, Stefan Wölfl, Xinlai Cheng
Published 2019-05-01

Imidazopyridines as Potent KDM5 Demethylase Inhibitors Promoting Reprogramming Efficiency of Human iPSCs

by Yasamin Dabiri, Rodrigo A. Gama-Brambila, Katerina Taškova, Kristina Herold, Stefanie Reuter, James Adjaye, Jochen Utikal, Ralf Mrowka, Jichang Wang, Miguel A. Andrade-Navarro, Xinlai Cheng
Published 2019-02-01

Baicalein Induces Apoptosis of Pancreatic Cancer Cells by Regulating the Expression of miR-139-3p and miR-196b-5p

by Danhui Ma, Danhui Ma, Sinuo Chen, Sinuo Chen, Heming Wang, Heming Wang, Jiayi Wei, Jiayi Wei, Hao Wu, Hao Wu, Hong Gao, Hong Gao, Xinlai Cheng, Taotao Liu, Taotao Liu, Shi-Hua Luo, Yicheng Zhao, Guangqi Song, Guangqi Song
Published 2021-04-01