A switch element in the autophagy E2 Atg3 mediates allosteric regulation across the lipidation cascade

by Yumei Zheng, Yu Qiu, Christy R. R. Grace, Xu Liu, Daniel J. Klionsky, Brenda A. Schulman
Published 2019-08-01

Data-independent acquisition method for ubiquitinome analysis reveals regulation of circadian biology

by Fynn M. Hansen, Maria C. Tanzer, Franziska Brüning, Isabell Bludau, Che Stafford, Brenda A. Schulman, Maria S. Robles, Ozge Karayel, Matthias Mann
Published 2021-01-01

Crystal structure of UBA2(ufd)-Ubc9: insights into E1-E2 interactions in Sumo pathways.

by Jing Wang, Asad M Taherbhoy, Harold W Hunt, Steven N Seyedin, David W Miller, Darcie J Miller, Danny T Huang, Brenda A Schulman
Published 2010-12-01

Structural Basis for a Reciprocal Regulation between SCF and CSN

by Radoslav I. Enchev, Daniel C. Scott, Paula C.A. da Fonseca, Anne Schreiber, Julie K. Monda, Brenda A. Schulman, Matthias Peter, Edward P. Morris
Published 2012-09-01

Integrative proteomics reveals principles of dynamic phosphosignaling networks in human erythropoiesis

by Özge Karayel, Peng Xu, Isabell Bludau, Senthil Velan Bhoopalan, Yu Yao, Freitas Colaco Ana Rita, Alberto Santos, Brenda A Schulman, Arno F Alpi, Mitchell J Weiss, Matthias Mann
Published 2020-12-01

Pathogenic bacteria target NEDD8-conjugated cullins to hijack host-cell signaling pathways.

by Grégory Jubelin, Frédéric Taieb, David M Duda, Yun Hsu, Ascel Samba-Louaka, Rika Nobe, Marie Penary, Claude Watrin, Jean-Philippe Nougayrède, Brenda A Schulman, C Erec Stebbins, Eric Oswald
Published 2010-09-01

Robust cullin-RING ligase function is established by a multiplicity of poly-ubiquitylation pathways

by Spencer Hill, Kurt Reichermeier, Daniel C Scott, Lorena Samentar, Jasmin Coulombe-Huntington, Luisa Izzi, Xiaojing Tang, Rebeca Ibarra, Thierry Bertomeu, Annie Moradian, Michael J Sweredoski, Nora Caberoy, Brenda A Schulman, Frank Sicheri, Mike Tyers, Gary Kleiger
Published 2019-12-01

Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3

by Hari B Kamadurai, Yu Qiu, Alan Deng, Joseph S Harrison, Chris MacDonald, Marcelo Actis, Patrick Rodrigues, Darcie J Miller, Judith Souphron, Steven M Lewis, Igor Kurinov, Naoaki Fujii, Michal Hammel, Robert Piper, Brian Kuhlman, Brenda A Schulman
Published 2013-08-01

Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients

by Lakshmi E Miller-Vedam, Bastian Bräuning, Katerina D Popova, Nicole T Schirle Oakdale, Jessica L Bonnar, Jesuraj R Prabu, Elizabeth A Boydston, Natalia Sevillano, Matthew J Shurtleff, Robert M Stroud, Charles S Craik, Brenda A Schulman, Adam Frost, Jonathan S Weissman
Published 2020-11-01

Quantifying the heterogeneity of macromolecular machines by mass photometry

by Adar Sonn-Segev, Katarina Belacic, Tatyana Bodrug, Gavin Young, Ryan T. VanderLinden, Brenda A. Schulman, Johannes Schimpf, Thorsten Friedrich, Phat Vinh Dip, Thomas U. Schwartz, Benedikt Bauer, Jan-Michael Peters, Weston B. Struwe, Justin L. P. Benesch, Nicholas G. Brown, David Haselbach, Philipp Kukura
Published 2020-04-01

Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay

by Myungjin Kim, Erin Sandford, Damian Gatica, Yu Qiu, Xu Liu, Yumei Zheng, Brenda A Schulman, Jishu Xu, Ian Semple, Seung-Hyun Ro, Boyoung Kim, R Nehir Mavioglu, Aslıhan Tolun, Andras Jipa, Szabolcs Takats, Manuela Karpati, Jun Z Li, Zuhal Yapici, Gabor Juhasz, Jun Hee Lee, Daniel J Klionsky, Margit Burmeister
Published 2016-01-01