“100 Years of progress in understanding insulin, its mechanism of action, and its roles in disease and diabetes therapy”

by C. Ronald Kahn
Published 2021-10-01

Insulin: A pacesetter for the shape of modern biomedical science and the Nobel Prize

by Jeffrey S. Flier, C. Ronald Kahn
Published 2021-10-01

Insulin action at a molecular level – 100 years of progress

by Morris F. White, C. Ronald Kahn
Published 2021-10-01

Interactions between host genetics and gut microbiome in diabetes and metabolic syndrome

by Siegfried Ussar, Shiho Fujisaka, C. Ronald Kahn
Published 2016-09-01

Hepatic deletion of p110α and p85α results in insulin resistance despite sustained IRS1-associated phosphatidylinositol kinase activity [version 2; referees: 1 approved, 2 approved...

by Aditi Chaudhari, Katarina Ejeskär, Yvonne Wettergren, C. Ronald Kahn, Victoria Rotter Sopasakis
Published 2018-06-01

A viral insulin-like peptide is a natural competitive antagonist of the human IGF-1 receptor

by Fa Zhang, Emrah Altindis, C. Ronald Kahn, Richard D. DiMarchi, Vasily Gelfanov
Published 2021-11-01

Reduction of the cholesterol sensor SCAP in the brains of mice causes impaired synaptic transmission and altered cognitive function.

by Ryo Suzuki, Heather A Ferris, Melissa J Chee, Eleftheria Maratos-Flier, C Ronald Kahn
Published 2013-01-01

Membrane metallo-endopeptidase (Neprilysin) regulates inflammatory response and insulin signaling in white preadipocytes

by Alfred K. Ramirez, Simon Dankel, Weikang Cai, Masaji Sakaguchi, Simon Kasif, C. Ronald Kahn
Published 2019-04-01

Differential Role of Insulin/IGF-1 Receptor Signaling in Muscle Growth and Glucose Homeostasis

by Brian T. O’Neill, Hans P.M.M. Lauritzen, Michael F. Hirshman, Graham Smyth, Laurie J. Goodyear, C. Ronald Kahn
Published 2015-05-01

Dietary leucine--an environmental modifier of insulin resistance acting on multiple levels of metabolism.

by Yazmin Macotela, Brice Emanuelli, Anneli M Bång, Daniel O Espinoza, Jeremie Boucher, Kirk Beebe, Walter Gall, C Ronald Kahn
Published 2011-01-01

Loss of Insulin Receptor in Osteoprogenitor Cells Impairs Structural Strength of Bone

by Kathryn Thrailkill, R. Clay Bunn, Charles Lumpkin, Elizabeth Wahl, Gael Cockrell, Lindsey Morris, C. Ronald Kahn, John Fowlkes, Jeffry S. Nyman
Published 2014-01-01

Myeloid cell-restricted insulin receptor deficiency protects against obesity-induced inflammation and systemic insulin resistance.

by Jan Mauer, Bhagirath Chaurasia, Leona Plum, Thomas Quast, Brigitte Hampel, Matthias Blüher, Waldemar Kolanus, C Ronald Kahn, Jens C Brüning
Published 2010-05-01

Complex mechanisms linking neurocognitive dysfunction to insulin resistance and other metabolic dysfunction [version 2; referees: 2 approved]

by Luke E. Stoeckel, Zoe Arvanitakis, Sam Gandy, Dana Small, C. Ronald Kahn, Alvaro Pascual-Leone, Aaron Pawlyk, Robert Sherwin, Philip Smith
Published 2016-06-01

Integrating Extracellular Flux Measurements and Genome-Scale Modeling Reveals Differences between Brown and White Adipocytes

by Alfred K. Ramirez, Matthew D. Lynes, Farnaz Shamsi, Ruidan Xue, Yu-Hua Tseng, C. Ronald Kahn, Simon Kasif, Jonathan M. Dreyfuss
Published 2017-12-01

Single-cell transcriptional networks in differentiating preadipocytes suggest drivers associated with tissue heterogeneity

by Alfred K. Ramirez, Simon N. Dankel, Bashir Rastegarpanah, Weikang Cai, Ruidan Xue, Mark Crovella, Yu-Hua Tseng, C. Ronald Kahn, Simon Kasif
Published 2020-04-01

TRPV1 neurons regulate β-cell function in a sex-dependent manner

by Joey Bou Karam, Weikang Cai, Rowaida Mohamed, Tianwen Huang, Lingqiong Meng, Erica Paige Homan, Ercument Dirice, C. Ronald Kahn, Abdelfattah El Ouaamari
Published 2018-12-01

Temporal dynamics of liver mitochondrial protein acetylation and succinylation and metabolites due to high fat diet and/or excess glucose or fructose.

by Jesse G Meyer, Samir Softic, Nathan Basisty, Matthew J Rardin, Eric Verdin, Bradford W Gibson, Olga Ilkayeva, Christopher B Newgard, C Ronald Kahn, Birgit Schilling
Published 2018-01-01

Homozygous receptors for insulin and not IGF-1 accelerate intimal hyperplasia in insulin resistance and diabetes

by Qian Li, Jialin Fu, Yu Xia, Weier Qi, Atsushi Ishikado, Kyoungmin Park, Hisashi Yokomizo, Qian Huang, Weikang Cai, Christian Rask-Madsen, C. Ronald Kahn, George L. King
Published 2019-09-01

Characterization of viral insulins reveals white adipose tissue-specific effects in mice

by Martina Chrudinová, François Moreau, Hye Lim Noh, Terezie Páníková, Lenka Žáková, Randall H. Friedline, Francisco A. Valenzuela, Jason K. Kim, Jiří Jiráček, C. Ronald Kahn, Emrah Altindis
Published 2021-02-01

Multi-dimensional Transcriptional Remodeling by Physiological Insulin In Vivo

by Thiago M. Batista, Ruben Garcia-Martin, Weikang Cai, Masahiro Konishi, Brian T. O’Neill, Masaji Sakaguchi, Jong Hun Kim, Dae Young Jung, Jason K. Kim, C. Ronald Kahn
Published 2019-03-01