Advances in the treatment of metabolic diseases

by Richard D. DiMarchi, Ph D
Published 2021-04-01

Peptide Conjugates with Small Molecules Designed to Enhance Efficacy and Safety

by Rongjun He, Brian Finan, John P. Mayer, Richard D. DiMarchi
Published 2019-05-01

A viral insulin-like peptide is a natural competitive antagonist of the human IGF-1 receptor

by Fa Zhang, Emrah Altindis, C. Ronald Kahn, Richard D. DiMarchi, Vasily Gelfanov
Published 2021-11-01

A Facile Procedure for One-Pot Stable Conjugation of Two Proglucagon Cysteine-Containing Peptide Analogs

by Rongjun He, Stephanie A. Mowery, Joseph Chabenne, Brian Finan, John P. Mayer, Richard D. DiMarchi
Published 2021-08-01

Gαs regulates Glucagon-Like Peptide 1 Receptor-mediated cyclic AMP generation at Rab5 endosomal compartment

by Shravan Babu Girada, Ramya S. Kuna, Shilpak Bele, Zhimeng Zhu, N.R. Chakravarthi, Richard D. DiMarchi, Prasenjit Mitra
Published 2017-10-01

Optimized GIP analogs promote body weight lowering in mice through GIPR agonism not antagonism

by Piotr A. Mroz, Brian Finan, Vasily Gelfanov, Bin Yang, Matthias H. Tschöp, Richard D. DiMarchi, Diego Perez-Tilve
Published 2019-02-01

Monomeric GLP-1/GIP/glucagon triagonism corrects obesity, hepatosteatosis, and dyslipidemia in female mice

by Sigrid Jall, Stephan Sachs, Christoffer Clemmensen, Brian Finan, Frauke Neff, Richard D. DiMarchi, Matthias H. Tschöp, Timo D. Müller, Susanna M. Hofmann
Published 2017-05-01

Molecular elements in FGF19 and FGF21 defining KLB/FGFR activity and specificity

by Archita Agrawal, Sebastian Parlee, Diego Perez-Tilve, Pengyun Li, Jia Pan, Piotr A. Mroz, Ann Maria Kruse Hansen, Birgitte Andersen, Brian Finan, Alexei Kharitonenkov, Richard D. DiMarchi
Published 2018-07-01

Fibroblast activation protein (FAP) as a novel metabolic target

by Miguel Angel Sánchez-Garrido, Kirk M. Habegger, Christoffer Clemmensen, Cassie Holleman, Timo D. Müller, Diego Perez-Tilve, Pengyun Li, Archita S. Agrawal, Brian Finan, Daniel J. Drucker, Matthias H. Tschöp, Richard D. DiMarchi, Alexei Kharitonenkov
Published 2016-10-01

Neuroprotective Effects and Treatment Potential of Incretin Mimetics in a Murine Model of Mild Traumatic Brain Injury

by Miaad Bader, Yazhou Li, David Tweedie, Nathan A. Shlobin, Adi Bernstein, Vardit Rubovitch, Luis B. Tovar-y-Romo, Luis B. Tovar-y-Romo, Richard D. DiMarchi, Barry J. Hoffer, Nigel H. Greig, Chaim G. Pick, Chaim G. Pick, Chaim G. Pick
Published 2020-01-01