Molecular, Biological and Structural Features of VL CDR-1 Rb44 Peptide, Which Targets the Microtubule Network in Melanoma Cells

by Natalia Girola, Pedro T. Resende-Lara, Carlos R. Figueiredo, Carlos R. Figueiredo, Mariana H. Massaoka, Ricardo A. Azevedo, Rodrigo L. O. R. Cunha, Luciano Polonelli, Luiz R. Travassos, Luiz R. Travassos
Published 2019-01-01

Blockade of MIF–CD74 Signalling on Macrophages and Dendritic Cells Restores the Antitumour Immune Response Against Metastatic Melanoma

by Carlos R. Figueiredo, Carlos R. Figueiredo, Ricardo A. Azevedo, Sasha Mousdell, Pedro T. Resende-Lara, Pedro T. Resende-Lara, Lucy Ireland, Almudena Santos, Natalia Girola, Rodrigo L. O. R. Cunha, Michael C. Schmid, Luciano Polonelli, Luiz R. Travassos, Ainhoa Mielgo
Published 2018-05-01

Transcriptome Profiling Reveals New Insights into the Immune Microenvironment and Upregulation of Novel Biomarkers in Metastatic Uveal Melanoma

by Yamini Krishna, Amelia Acha-Sagredo, Dorota Sabat-Pośpiech, Natalie Kipling, Kim Clarke, Carlos R. Figueiredo, Helen Kalirai, Sarah E. Coupland
Published 2020-09-01

A novel cell-penetrating peptide derived from WT1 enhances p53 activity, induces cell senescence and displays antimelanoma activity in xeno- and syngeneic systems

by Mariana H. Massaoka, Alisson L. Matsuo, Carlos R. Figueiredo, Natalia Girola, Camyla F. Faria, Ricardo A. Azevedo, Luiz R. Travassos
Published 2014-01-01

FTY720 induces apoptosis in B16F10-NEX2 murine melanoma cells, limits metastatic development in vivo, and modulates the immune system

by Felipe V. Pereira, Denise C. Arruda, Carlos R. Figueiredo, Mariana H. Massaoka, Alisson L. Matsuo, Valquiria Bueno, Elaine G. Rodrigues
Published 2013-07-01

Neolignans from Nectandra megapotamica (Lauraceae) Display in vitro Cytotoxic Activity and Induce Apoptosis in Leukemia Cells

by Vitor Ponci, Carlos R. Figueiredo, Mariana H. Massaoka, Camyla F. de Farias, Alisson L. Matsuo, Patricia Sartorelli, João Henrique G. Lago
Published 2015-07-01

Chemical Composition and Cytotoxicity Evaluation of Essential Oil from Leaves of Casearia Sylvestris, Its Main Compound α-Zingiberene and Derivatives

by Patricia Sartorelli, Marisi G. Soares, Rafael C. Guadagnin, Carlos R. Figueiredo, Alisson L. Matsuo, João Henrique G. Lago, Diego Dinis Bou
Published 2013-08-01

Cytotoxic and Antimicrobial Constituents from the Essential Oil of Lippia alba (Verbenaceae)

by Nara O. dos Santos, Renata C. Pascon, Marcelo A. Vallim, Carlos R. Figueiredo, Marisi G. Soares, João Henrique G. Lago, Patricia Sartorelli
Published 2016-08-01

Immunomodulatory Protective Effects of Rb9 Cyclic-Peptide in a Metastatic Melanoma Setting and the Involvement of Dendritic Cells

by Fabrício C. Machado, Fabrício C. Machado, Natália Girola, Natália Girola, Vera S. C. Maia, Vera S. C. Maia, Patrícia C. Bergami-Santos, Patrícia C. Bergami-Santos, Alice S. Morais, Ricardo A. Azevedo, Carlos R. Figueiredo, Carlos R. Figueiredo, José A. M. Barbuto, José A. M. Barbuto, Luiz R. Travassos, Luiz R. Travassos
Published 2020-01-01

Chemical Composition and In Vitro Cytotoxic and Antimicrobial Activities of the Essential Oil from Leaves of Zanthoxylum monogynum St. Hill (Rutaceae)

by Fernanda B. da Silva, Nara O. dos Santos, Renata C. Pascon, Marcelo A. Vallim, Carlos R. Figueiredo, Roberto C. Campos Martins, Patricia Sartorelli
Published 2017-05-01

ISOLATION OF CYTOTOXIC NEOLIGNANS FROM Saururus cernuus L. (SAURURACEAE) USING IONIC LIQUID IN THE MICROWAVE ASSISTED EXTRACTION (MAE)

by Juliana R. Brito, Fernanda F. Camilo, Carlos R. Figueiredo, Ricardo A. Azevedo, Paulete Romoff, Fátima O. S. Buturi, Oriana A. Fávero, João Henrique G. Lago, Edgard A. Ferreira

Applying Single-Cell Technology in Uveal Melanomas: Current Trends and Perspectives for Improving Uveal Melanoma Metastasis Surveillance and Tumor Profiling

by Mona Meng Wang, Chuanfei Chen, Myoe Naing Lynn, Carlos R. Figueiredo, Wei Jian Tan, Tong Seng Lim, Sarah E. Coupland, Sarah E. Coupland, Anita Sook Yee Chan, Anita Sook Yee Chan
Published 2021-01-01

C7a, a Biphosphinic Cyclopalladated Compound, Efficiently Controls the Development of a Patient-Derived Xenograft Model of Adult T Cell Leukemia/Lymphoma

by Carlos R. Figueiredo, Susan J. Marriott, Elaine G. Rodrigues, Antonio C.F. Caires, Karina P. Gimenes, Lorena A. Pinto, Maria Fernanda Rios Grassi, Gerold Feuer, Ana B. Guimaraes-Correa, Lindsey B. Crawford, Luiz R. Travassos
Published 2011-07-01

Jacaranone induces apoptosis in melanoma cells via ROS-mediated downregulation of Akt and p38 MAPK activation and displays antitumor activity in vivo.

by Mariana H Massaoka, Alisson L Matsuo, Carlos R Figueiredo, Camyla F Farias, Natália Girola, Denise C Arruda, Jorge A B Scutti, Paulete Romoff, Oriana A Favero, Marcelo J P Ferreira, João H G Lago, Luiz R Travassos
Published 2012-01-01